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| GeneID |
8542
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| Symbol |
APOL1
|
| Synonyms |
APO-L|APOL|APOL-I
|
| Description |
apolipoprotein L, 1 |
| See related |
HGNC:618|MIM:603743|Ensembl:ENSG00000100342|HPRD:04774| |
| Locus tag |
RP1-68O2.2 |
| Gene type |
protein-coding |
| Map location |
22q13.1 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
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| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| FAM117B | 0.96 | 0.97 | | |
| AL096711.2 | 0.96 | 0.97 | | |
| CLASP1 | 0.96 | 0.97 | | |
| NCAM1 | 0.96 | 0.96 | | |
| BRD3 | 0.96 | 0.96 | | |
| ZNF445 | 0.95 | 0.97 | | |
| BCORL1 | 0.95 | 0.96 | | |
| GPR161 | 0.95 | 0.92 | | |
| SRGAP2 | 0.95 | 0.97 | | |
| KIAA1549 | 0.95 | 0.97 | | |
Top 10 negatively co-expressed genes | | C5orf53 | -0.71 | -0.82 | | |
| AIFM3 | -0.71 | -0.81 | | |
| HLA-F | -0.70 | -0.79 | | |
| ALDOC | -0.69 | -0.74 | | |
| HEPN1 | -0.69 | -0.78 | | |
| SERPINB6 | -0.69 | -0.77 | | |
| TSC22D4 | -0.69 | -0.83 | | |
| S100B | -0.69 | -0.88 | | |
| FBXO2 | -0.68 | -0.66 | | |
| CLU | -0.68 | -0.73 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005515 | protein binding | IPI | | 12621437 |
| GO:0005319 | lipid transporter activity | IEA | | - |
| GO:0005254 | chloride channel activity | IDA | | 16020735 |
| GO:0008289 | lipid binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0008202 | steroid metabolic process | IEA | | - |
| GO:0008203 | cholesterol metabolic process | IEA | | - |
| GO:0019835 | cytolysis | IDA | | 12621437 |17192540 |
| GO:0006821 | chloride transport | IDA | | 16020735 |
| GO:0006629 | lipid metabolic process | IEA | | - |
| GO:0006869 | lipid transport | IEA | | - |
| GO:0031640 | killing of cells of another organism | IDA | | 12621437 |17192540 |
| GO:0042157 | lipoprotein metabolic process | IEA | | - |
| GO:0045087 | innate immune response | IDA | | 17192540 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005576 | extracellular region | IEA | | - |
| GO:0005615 | extracellular space | IDA | | 17192540 |
| GO:0031224 | intrinsic to membrane | IC | | 16020735 |
| GO:0034364 | high-density lipoprotein particle | IDA | | 9325276 |
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