Gene Page: RANBP9

Summary
GeneID  10048
Symbol  RANBP9
Synonyms  RANBPM
Description  RAN binding protein 9
See related  HGNC:13727|MIM:603854|Ensembl:ENSG00000010017|HPRD:04835|
Locus tag  -
Gene type  protein-coding
Map location  6p23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0159 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0833 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MAP3K10.780.62
AP001979.10.770.66
TSPAN90.770.64
SPATA130.770.67
ZNF5030.760.64
TRERF10.760.77
FOXP40.750.66
RARA0.750.67
MEIS10.750.63
AC010997.10.750.59
Top 10 negatively co-expressed genes
AF347015.21-0.45-0.47
C1orf54-0.42-0.48
SYCP3-0.41-0.49
AF347015.31-0.40-0.41
MT-CO2-0.40-0.40
VAMP5-0.39-0.40
GNG11-0.38-0.42
HIGD1B-0.37-0.36
CLEC2B-0.37-0.42
IL32-0.37-0.45
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI12220523 |12421467 |14500717 
GO:0008536Ran GTPase bindingTAS9817760 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006461protein complex assemblyTAS9817760 
GO:0007020microtubule nucleationNAS12220523 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005875microtubule associated complexTAS9817760 
GO:0005634nucleusIDA12220523 
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARAIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFMandrogen receptor-HPRD,BioGRID12361945 
AXLJTK11 | UFOAXL receptor tyrosine kinaseAxl interacts with RanBPM.BIND12470648 
BACE1ASP2 | BACE | FLJ90568 | HSPC104 | KIAA1149beta-site APP-cleaving enzyme 1BACE1 interacts with RANBP9 (RANBPM). This interaction was modelled on a demonstrated interaction between mouse BACE1 and human RANBPM.BIND15606899 
CALB1CALBcalbindin 1, 28kDa-HPRD,BioGRID12684061 
DISC1C1orf136 | FLJ13381 | FLJ21640 | FLJ25311 | FLJ41105 | KIAA0457 | SCZD9disrupted in schizophrenia 1-HPRD,BioGRID12812986 
DISC-1 interacts with RanBPM.BIND12812986 
DYRK1BMIRKdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B-HPRD,BioGRID14500717 
FMR1FMRP | FRAXA | MGC87458 | POF | POF1fragile X mental retardation 1FMR1 (FMRP) interacts with RANBP9 (RanBPM).BIND15381419 
HIPK2DKFZp686K02111 | FLJ23711 | PRO0593homeodomain interacting protein kinase 2The nuclear protein kinase HIPK2 interacts with the Ran binding protein RanBPMBIND12220523 
-HPRD,BioGRID12220523 
ITGB2CD18 | LAD | LCAMB | LFA-1 | MAC-1 | MF17 | MFI7integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)RanBPM interacts with beta-2 integrin LFA-1.BIND14722085 
L1CAMCAML1 | CD171 | HSAS | HSAS1 | MASA | MIC5 | N-CAML1 | S10 | SPG1L1 cell adhesion moleculeL1CAM interacts with RanBPM.BIND16000162 
METAUTS9 | HGFR | RCCP2 | c-Metmet proto-oncogene (hepatocyte growth factor receptor)-HPRD,BioGRID12147692 
MPHOSPH8FLJ35237 | HSMPP8 | TWA3 | mpp8M-phase phosphoprotein 8-HPRD,BioGRID12559565 
NR3C1GCCR | GCR | GR | GRLnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)Affinity Capture-Western
Two-hybrid		BioGRID12361945 
RANARA24 | Gsp1 | TC4RAN, member RAS oncogene family-HPRD,BioGRID9817760 
RNPS1E5.1 | MGC117332RNA binding protein S1, serine-rich domainAffinity Capture-MSBioGRID17353931 
S100A7PSOR1 | S100A7cS100 calcium binding protein A7-HPRD,BioGRID12421467 
UCHL1PARK5 | PGP9.5 | Uch-L1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)-HPRD,BioGRID12082530 
USP11UHX1ubiquitin specific peptidase 11-HPRD,BioGRID12084015 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_MET_PATHWAY 8060All SZGR genes in this pathway
PID_AR_PATHWAY 6146All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_L1CAM_INTERACTIONS 8662All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
DITTMER_PTHLH_TARGETS_UP 11268All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_DN 214133All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
DEN_INTERACT_WITH_LCA5 2621All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_6P24_P22_AMPLICON 2117All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS 185114All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
JIANG_VHL_TARGETS 13891All SZGR genes in this pathway
JI_RESPONSE_TO_FSH_DN 5843All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_DN 264168All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 473224All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP 673430All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_UP 5541All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
ABRAMSON_INTERACT_WITH_AIRE 4533All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1015075141A,m8hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-1445085141Ahsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-200bc/4296816881A,m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-2087537591Ahsa-miR-208AUAAGACGAGCAAAAAGCUUGU
miR-21464701Ahsa-miR-214brainACAGCAGGCACAGACAGGCAG
miR-25/32/92/363/3678108161Ahsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-265175231Ahsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-30-5p1371431Ahsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-323501507m8hsa-miR-323brainGCACAUUACACGGUCGACCUCU
miR-4107187241Ahsa-miR-410AAUAUAACACAGAUGGCCUGU
miR-411748754m8hsa-miR-411AACACGGUCCACUAACCCUCAGU
miR-4963753811Ahsa-miR-496AUUACAUGGCCAAUCUC
miR-4997537591Ahsa-miR-499UUAAGACUUGCAGUGAUGUUUAA
miR-505478484m8hsa-miR-505GUCAACACUUGCUGGUUUCCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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