The pahtway p484 has 80 genes in the original annotation. Currently, there are 60 genes in SZGR (with evidence in schizophrenia) that are present at this pathway.
|
Gene ID |
Symbol |
Synonyms |
Official Full Name |
Start Site |
End Site |
Location |
5599 | MAPK8 | JNK | JNK-46 | JNK1 | JNK1A2 | JNK21B1/2 | PRKM8 | SAPK1 | SAPK1c | mitogen-activated protein kinase 8 | | | 10q11.22 |
5795 | PTPRJ | CD148 | DEP1 | HPTPeta | R-PTP-ETA | SCC1 | protein tyrosine phosphatase, receptor type J | | | 11p11.2 |
3265 | HRAS | C-BAS/HAS | C-H-RAS | C-HA-RAS1 | CTLO | H-RASIDX | HAMSV | HRAS1 | RASH1 | p21ras | Harvey rat sarcoma viral oncogene homolog | | | 11p15.5 |
5058 | PAK1 | PAKalpha | p21 protein (Cdc42/Rac)-activated kinase 1 | | | 11q13.5-q14.1 |
9846 | GAB2 | - | GRB2 associated binding protein 2 | | | 11q14.1 |
2113 | ETS1 | ETS-1 | EWSR2 | c-ets-1 | p54 | ETS proto-oncogene 1, transcription factor | | | 11q23.3 |
867 | CBL | C-CBL | CBL2 | FRA11B | NSLL | RNF55 | Cbl proto-oncogene, E3 ubiquitin protein ligase | | | 11q23.3 |
5908 | RAP1B | K-REV | RAL1B | RAP1B, member of RAS oncogene family | | | 12q14 |
5781 | PTPN11 | BPTP3 | CFC | JMML | METCDS | NS1 | PTP-1D | PTP2C | SH-PTP2 | SH-PTP3 | SHP2 | protein tyrosine phosphatase, non-receptor type 11 | | | 12q24 |
382 | ARF6 | - | ADP ribosylation factor 6 | | | 14q21.3 |
8650 | NUMB | C14orf41 | S171 | c14_5527 | numb homolog (Drosophila) | | | 14q24.3 |
207 | AKT1 | AKT | CWS6 | PKB | PKB-ALPHA | PRKBA | RAC | RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 | | | 14q32.32 |
5604 | MAP2K1 | CFC3 | MAPKK1 | MEK1 | MKK1 | PRKMK1 | mitogen-activated protein kinase kinase 1 | | | 15q22.1-q22.33 |
5595 | MAPK3 | ERK-1 | ERK1 | ERT2 | HS44KDAP | HUMKER1A | P44ERK1 | P44MAPK | PRKM3 | p44-ERK1 | p44-MAPK | mitogen-activated protein kinase 3 | | | 16p11.2 |
64223 | MLST8 | GBL | GbetaL | LST8 | POP3 | WAT1 | MTOR associated protein, LST8 homolog | | | 16p13.3 |
50855 | PARD6A | PAR-6A | PAR6 | PAR6C | PAR6alpha | TAX40 | TIP-40 | par-6 family cell polarity regulator alpha | | | 16q22.1 |
57610 | RANBP10 | - | RAN binding protein 10 | | | 16q22.1 |
9564 | BCAR1 | CAS | CAS1 | CASS1 | CRKAS | P130Cas | breast cancer anti-estrogen resistance 1 | | | 16q23.1 |
1398 | CRK | CRKII | p38 | v-crk avian sarcoma virus CT10 oncogene homolog | | | 17p13.3 |
3837 | KPNB1 | IMB1 | IPO1 | IPOB | Impnb | NTF97 | karyopherin subunit beta 1 | | | 17q21.32 |
2885 | GRB2 | ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084 | NCKAP2 | growth factor receptor bound protein 2 | | | 17q24-q25 |
9146 | HGS | HRS | hepatocyte growth factor-regulated tyrosine kinase substrate | | | 17q25 |
57521 | RPTOR | KOG1 | Mip1 | regulatory associated protein of MTOR, complex 1 | | | 17q25.3 |
5605 | MAP2K2 | CFC4 | MAPKK2 | MEK2 | MKK2 | PRKMK2 | mitogen-activated protein kinase kinase 2 | | | 19p13.3 |
208 | AKT2 | HIHGHH | PKBB | PKBBETA | PRKBB | RAC-BETA | v-akt murine thymoma viral oncogene homolog 2 | | | 19q13.1-q13.2 |
5906 | RAP1A | C21KG | G-22K | KREV-1 | KREV1 | RAP1 | SMGP21 | RAP1A, member of RAS oncogene family | | | 1p13.3 |
998 | CDC42 | CDC42Hs | G25K | TKS | cell division cycle 42 | | | 1p36.1 |
2475 | MTOR | FRAP | FRAP1 | FRAP2 | RAFT1 | RAPT1 | SKS | mechanistic target of rapamycin | | | 1p36.2 |
5590 | PRKCZ | PKC-ZETA | PKC2 | protein kinase C zeta | | | 1p36.33-p36.2 |
54453 | RIN2 | MACS | RASSF4 | Ras and Rab interactor 2 | | | 20p11.22 |
6714 | SRC | ASV | SRC1 | c-SRC | p60-Src | SRC proto-oncogene, non-receptor tyrosine kinase | | | 20q12-q13 |
5335 | PLCG1 | NCKAP3 | PLC-II | PLC1 | PLC148 | PLCgamma1 | phospholipase C gamma 1 | | | 20q12-q13.1 |
5770 | PTPN1 | PTP1B | protein tyrosine phosphatase, non-receptor type 1 | | | 20q13.1-q13.2 |
1399 | CRKL | - | v-crk avian sarcoma virus CT10 oncogene homolog-like | | | 22q11.21 |
5594 | MAPK1 | ERK | ERK-2 | ERK2 | ERT1 | MAPK2 | P42MAPK | PRKM1 | PRKM2 | p38 | p40 | p41 | p41mapk | p42-MAPK | mitogen-activated protein kinase 1 | | | 22q11.21 |
8440 | NCK2 | GRB4 | NCKbeta | NCK adaptor protein 2 | | | 2q12 |
50649 | ARHGEF4 | ASEF | ASEF1 | GEF4 | STM6 | Rho guanine nucleotide exchange factor 4 | | | 2q22 |
1499 | CTNNB1 | CTNNB | MRD19 | armadillo | catenin beta 1 | | | 3p21 |
387 | RHOA | ARH12 | ARHA | RHO12 | RHOH12 | ras homolog family member A | | | 3p21.3 |
5868 | RAB5A | RAB5 | RAB5A, member RAS oncogene family | | | 3p24.3 |
5894 | RAF1 | CMD1NN | CRAF | NS5 | Raf-1 | c-Raf | Raf-1 proto-oncogene, serine/threonine kinase | | | 3p25 |
4690 | NCK1 | NCK | NCKalpha | nck-1 | NCK adaptor protein 1 | | | 3q21 |
5290 | PIK3CA | CLOVE | CWS5 | MCAP | MCM | MCMTC | PI3K | p110-alpha | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | | | 3q26.3 |
5062 | PAK2 | PAK65 | PAKgamma | p21 protein (Cdc42/Rac)-activated kinase 2 | | | 3q29 |
1977 | EIF4E | AUTS19 | CBP | EIF4E1 | EIF4EL1 | EIF4F | eIF-4E | eukaryotic translation initiation factor 4E | | | 4q23 |
2549 | GAB1 | - | GRB2 associated binding protein 1 | | | 4q31.21 |
4214 | MAP3K1 | MAPKKK1 | MEKK | MEKK 1 | MEKK1 | SRXY6 | mitogen-activated protein kinase kinase kinase 1 | | | 5q11.2 |
5295 | PIK3R1 | AGM7 | GRB1 | IMD36 | p85 | p85-ALPHA | phosphoinositide-3-kinase regulatory subunit 1 | | | 5q13.1 |
324 | APC | BTPS2 | DP2 | DP2.5 | DP3 | GS | PPP1R46 | adenomatous polyposis coli | | | 5q21-q22 |
1958 | EGR1 | AT225 | G0S30 | KROX-24 | NGFI-A | TIS8 | ZIF-268 | ZNF225 | early growth response 1 | | | 5q31.1 |
1495 | CTNNA1 | CAP102 | catenin alpha 1 | | | 5q31.2 |
10048 | RANBP9 | BPM-L | BPM90 | RANBPM | RanBP7 | RAN binding protein 9 | | | 6p23 |
5879 | RAC1 | MIG5 | Rac-1 | TC-25 | p21-Rac1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | | | 7p22 |
3082 | HGF | DFNB39 | F-TCF | HGFB | HPTA | SF | hepatocyte growth factor | | | 7q21.1 |
8976 | WASL | N-WASP | NWASP | WASPB | Wiskott-Aldrich syndrome-like | | | 7q31.3 |
1978 | EIF4EBP1 | 4E-BP1 | 4EBP1 | BP-1 | PHAS-I | eukaryotic translation initiation factor 4E binding protein 1 | | | 8p12 |
64798 | DEPTOR | DEP.6 | DEPDC6 | DEP domain containing MTOR-interacting protein | | | 8q24.12 |
5747 | PTK2 | FADK | FAK | FAK1 | FRNK | PPP1R71 | p125FAK | pp125FAK | protein tyrosine kinase 2 | | | 8q24.3 |
2889 | RAPGEF1 | C3G | GRF2 | Rap guanine nucleotide exchange factor 1 | | | 9q34.3 |
30011 | SH3KBP1 | CD2BP3 | CIN85 | GIG10 | HSB-1 | HSB1 | MIG18 | SH3-domain kinase binding protein 1 | | | Xp22.1-p21.3 |