Gene Page: MAP2K1

Summary
GeneID  5604
Symbol  MAP2K1
Synonyms  MAPKK1|MEK1|MKK1|PRKMK1
Description  mitogen-activated protein kinase kinase 1
See related  HGNC:6840|MIM:176872|Ensembl:ENSG00000169032|HPRD:01469|
Locus tag  -
Gene type  protein-coding
Map location  15q22.1-q22.33
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PGD0.970.93
RFWD20.970.94
EIF4A10.960.95
XRN20.960.93
TRAFD10.960.91
C12orf410.960.95
BZW20.960.93
KDM10.960.92
SIAH10.960.92
NARS20.960.94
Top 10 negatively co-expressed genes
HLA-F-0.76-0.79
AF347015.27-0.75-0.90
AIFM3-0.74-0.78
AF347015.31-0.74-0.87
MT-CO2-0.74-0.89
AF347015.33-0.74-0.88
MT-CYB-0.73-0.89
C5orf53-0.72-0.71
AF347015.8-0.72-0.89
AF347015.15-0.71-0.88
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0004708MAP kinase kinase activityTAS8388392 
GO:0005515protein bindingIPI15299019 
GO:0005524ATP bindingIEA-
GO:0004674protein serine/threonine kinase activityIEA-
GO:0004713protein tyrosine kinase activityIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030182neuron differentiationIEAneuron (GO term level: 8)-
GO:0006468protein amino acid phosphorylationIEA-
GO:0007265Ras protein signal transductionEXP11520933 
GO:0006935chemotaxisTAS10570282 
GO:0006928cell motionTAS10912793 
GO:0030216keratinocyte differentiationIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARAFA-RAF | ARAF1 | PKS2 | RAFA1v-raf murine sarcoma 3611 viral oncogene homologMEK1 interacts with A-Raf.BIND8621729 
BRAFB-RAF1 | BRAF1 | FLJ95109 | MGC126806 | MGC138284 | RAFB1v-raf murine sarcoma viral oncogene homolog B1MEK1 interacts with B-Raf.BIND8621729 
-HPRD7731720 
CPNE1COPN1 | CPN1 | MGC1142copine I-HPRD12522145 
CPNE4COPN4 | CPN4 | MGC15604copine IV-HPRD12522145 
GRB10GRB-IR | Grb-10 | IRBP | KIAA0207 | MEG1 | RSSgrowth factor receptor-bound protein 10-HPRD,BioGRID9553107 
HRASC-BAS/HAS | C-H-RAS | C-HA-RAS1 | CTLO | H-RASIDX | HAMSV | HRAS1 | K-RAS | N-RAS | RASH1v-Ha-ras Harvey rat sarcoma viral oncogene homolog-HPRD,BioGRID7969158 
KSR2FLJ25965kinase suppressor of ras 2-HPRD,BioGRID12975377 
MAP2K1MAPKK1 | MEK1 | MKK1 | PRKMK1mitogen-activated protein kinase kinase 1Biochemical ActivityBioGRID8226933 
MAP3K1MAPKKK1 | MEKK | MEKK1mitogen-activated protein kinase kinase kinase 1Affinity Capture-WesternBioGRID10969079 
MEKK1 interacts with MEK1.BIND10969079 
MAP3K11MGC17114 | MLK-3 | MLK3 | PTK1 | SPRKmitogen-activated protein kinase kinase kinase 11MEK1 interacts with MLK3.BIND15258589 
MAP3K4FLJ42439 | KIAA0213 | MAPKKK4 | MEKK4 | MTK1 | PRO0412mitogen-activated protein kinase kinase kinase 4-HPRD,BioGRID9841871 
MAP3K8COT | EST | ESTF | FLJ10486 | TPL2 | Tpl-2 | c-COTmitogen-activated protein kinase kinase kinase 8Biochemical ActivityBioGRID8631303 
MAPK1ERK | ERK2 | ERT1 | MAPK2 | P42MAPK | PRKM1 | PRKM2 | p38 | p40 | p41 | p41mapkmitogen-activated protein kinase 1MEK1 interacts with and phosphorylates ERK2. This interaction is modeled on a demonstrated interaction between human MEK1 and rat ERK2.BIND11134045 
Affinity Capture-Western
Biochemical Activity
Reconstituted Complex
Two-hybrid		BioGRID10757792 |11266467 
|11279118 |11352917 
|11823456 |12697810 
MAPK14CSBP1 | CSBP2 | CSPB1 | EXIP | Mxi2 | PRKM14 | PRKM15 | RK | SAPK2A | p38 | p38ALPHAmitogen-activated protein kinase 14-HPRD12697810 
MAPK3ERK1 | HS44KDAP | HUMKER1A | MGC20180 | P44ERK1 | P44MAPK | PRKM3mitogen-activated protein kinase 3Affinity Capture-Western
Biochemical Activity
Co-localization
Reconstituted Complex
Two-hybrid		BioGRID8226933 |8626767 
|9006895 |9733512 
|10748187 
MEK1 interacts with ERK1 via a conserved docking site in MEKBIND11134045 
-HPRD8226933 |8626767 
|10748187 
MAPK8IP3DKFZp762N1113 | FLJ00027 | JIP3 | JSAP1 | KIAA1066 | SYD2mitogen-activated protein kinase 8 interacting protein 3-HPRD,BioGRID10523642 |11044439 
MAPKSP1MAP2K1IP1 | MAPBP | MP1MAPK scaffold protein 1-HPRD,BioGRID9733512 
MYCbHLHe39 | c-Mycv-myc myelocytomatosis viral oncogene homolog (avian)-HPRD7957875 
PEBP1HCNP | PBP | PEBP | RKIPphosphatidylethanolamine binding protein 1-HPRD,BioGRID10757792 
PEBP4CORK-1 | CORK1 | GWTM1933 | MGC22776 | PRO4408phosphatidylethanolamine-binding protein 4-HPRD,BioGRID15302887 
hPEBP4 interacts with MEK1. This interaction was modeled on a demonstrated interaction between human hPEBP4 and mouse MEK1.BIND15302887 
PLAUATF | UPA | URK | UROKINASE | u-PAplasminogen activator, urokinasePhenotypic SuppressionBioGRID10402467 
RAF1CRAF | NS5 | Raf-1 | c-Rafv-raf-1 murine leukemia viral oncogene homolog 1Reconstituted ComplexBioGRID10757792 
Raf interacts with and phosphorylates Mek1BIND14724641 
MEK1 interacts with and is phosphorylated by Raf-1. This interaction was modeled on a demonstrated interaction between human MEK1 and Raf-1 from an unspecified species.BIND15866172 
MEK1 interacts with c-RafBIND8621729 
-HPRD11604401 
ROBLD3ENDAP | HSPC003 | MAPBPIP | MAPKSP1AP | p14roadblock domain containing 3Affinity Capture-WesternBioGRID11266467 
RPS6KA2HU-2 | MAPKAPK1C | RSK | RSK3 | S6K-alpha | S6K-alpha2 | p90-RSK3 | pp90RSK3ribosomal protein S6 kinase, 90kDa, polypeptide 2-HPRD8939914 
TRAF3CAP-1 | CD40bp | CRAF1 | LAP1TNF receptor-associated factor 3-HPRD8626767 
VAV1VAVvav 1 guanine nucleotide exchange factorAffinity Capture-WesternBioGRID8900182 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_MAPK_SIGNALING_PATHWAY 267205All SZGR genes in this pathway
KEGG_ERBB_SIGNALING_PATHWAY 8771All SZGR genes in this pathway
KEGG_CHEMOKINE_SIGNALING_PATHWAY 190128All SZGR genes in this pathway
KEGG_OOCYTE_MEIOSIS 11479All SZGR genes in this pathway
KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION 11581All SZGR genes in this pathway
KEGG_DORSO_VENTRAL_AXIS_FORMATION 2521All SZGR genes in this pathway
KEGG_VEGF_SIGNALING_PATHWAY 7653All SZGR genes in this pathway
KEGG_FOCAL_ADHESION 201138All SZGR genes in this pathway
KEGG_GAP_JUNCTION 9068All SZGR genes in this pathway
KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY 10288All SZGR genes in this pathway
KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 13792All SZGR genes in this pathway
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 10889All SZGR genes in this pathway
KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 7556All SZGR genes in this pathway
KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY 7958All SZGR genes in this pathway
KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 9771All SZGR genes in this pathway
KEGG_LONG_TERM_POTENTIATION 7057All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 126103All SZGR genes in this pathway
KEGG_LONG_TERM_DEPRESSION 7053All SZGR genes in this pathway
KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 216144All SZGR genes in this pathway
KEGG_INSULIN_SIGNALING_PATHWAY 137103All SZGR genes in this pathway
KEGG_GNRH_SIGNALING_PATHWAY 10177All SZGR genes in this pathway
KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION 8659All SZGR genes in this pathway
KEGG_MELANOGENESIS 10280All SZGR genes in this pathway
KEGG_PRION_DISEASES 3528All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_COLORECTAL_CANCER 6247All SZGR genes in this pathway
KEGG_RENAL_CELL_CARCINOMA 7060All SZGR genes in this pathway
KEGG_PANCREATIC_CANCER 7056All SZGR genes in this pathway
KEGG_ENDOMETRIAL_CANCER 5245All SZGR genes in this pathway
KEGG_GLIOMA 6556All SZGR genes in this pathway
KEGG_PROSTATE_CANCER 8975All SZGR genes in this pathway
KEGG_THYROID_CANCER 2926All SZGR genes in this pathway
KEGG_MELANOMA 7157All SZGR genes in this pathway
KEGG_BLADDER_CANCER 4233All SZGR genes in this pathway
KEGG_CHRONIC_MYELOID_LEUKEMIA 7359All SZGR genes in this pathway
KEGG_ACUTE_MYELOID_LEUKEMIA 6047All SZGR genes in this pathway
KEGG_NON_SMALL_CELL_LUNG_CANCER 5447All SZGR genes in this pathway
BIOCARTA_AT1R_PATHWAY 3628All SZGR genes in this pathway
BIOCARTA_SPPA_PATHWAY 2218All SZGR genes in this pathway
BIOCARTA_BCR_PATHWAY 3728All SZGR genes in this pathway
BIOCARTA_BIOPEPTIDES_PATHWAY 4535All SZGR genes in this pathway
BIOCARTA_CDMAC_PATHWAY 1615All SZGR genes in this pathway
BIOCARTA_CCR3_PATHWAY 2321All SZGR genes in this pathway
BIOCARTA_CERAMIDE_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_CXCR4_PATHWAY 2422All SZGR genes in this pathway
BIOCARTA_EGF_PATHWAY 3125All SZGR genes in this pathway
BIOCARTA_EPO_PATHWAY 1913All SZGR genes in this pathway
BIOCARTA_ECM_PATHWAY 2417All SZGR genes in this pathway
BIOCARTA_ERK_PATHWAY 2822All SZGR genes in this pathway
BIOCARTA_FCER1_PATHWAY 4130All SZGR genes in this pathway
BIOCARTA_FMLP_PATHWAY 3929All SZGR genes in this pathway
BIOCARTA_GH_PATHWAY 2822All SZGR genes in this pathway
BIOCARTA_HCMV_PATHWAY 1716All SZGR genes in this pathway
BIOCARTA_IGF1_PATHWAY 2116All SZGR genes in this pathway
BIOCARTA_IL2_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_IL3_PATHWAY 1511All SZGR genes in this pathway
BIOCARTA_IL6_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_GLEEVEC_PATHWAY 2317All SZGR genes in this pathway
BIOCARTA_INSULIN_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_INTEGRIN_PATHWAY 3829All SZGR genes in this pathway
BIOCARTA_KERATINOCYTE_PATHWAY 4638All SZGR genes in this pathway
BIOCARTA_PYK2_PATHWAY 3124All SZGR genes in this pathway
BIOCARTA_EGFR_SMRTE_PATHWAY 1111All SZGR genes in this pathway
BIOCARTA_MAPK_PATHWAY 8768All SZGR genes in this pathway
BIOCARTA_IGF1R_PATHWAY 2320All SZGR genes in this pathway
BIOCARTA_NGF_PATHWAY 1813All SZGR genes in this pathway
BIOCARTA_NFAT_PATHWAY 5645All SZGR genes in this pathway
BIOCARTA_PDGF_PATHWAY 3225All SZGR genes in this pathway
BIOCARTA_CDK5_PATHWAY 1111All SZGR genes in this pathway
BIOCARTA_RAS_PATHWAY 2320All SZGR genes in this pathway
BIOCARTA_NKCELLS_PATHWAY 2013All SZGR genes in this pathway
BIOCARTA_HER2_PATHWAY 2217All SZGR genes in this pathway
BIOCARTA_MAL_PATHWAY 1917All SZGR genes in this pathway
BIOCARTA_BARR_MAPK_PATHWAY 1211All SZGR genes in this pathway
BIOCARTA_BARRESTIN_SRC_PATHWAY 1514All SZGR genes in this pathway
BIOCARTA_MET_PATHWAY 3730All SZGR genes in this pathway
BIOCARTA_GPCR_PATHWAY 3731All SZGR genes in this pathway
BIOCARTA_SPRY_PATHWAY 1815All SZGR genes in this pathway
BIOCARTA_TCR_PATHWAY 4937All SZGR genes in this pathway
BIOCARTA_TGFB_PATHWAY 1914All SZGR genes in this pathway
BIOCARTA_TPO_PATHWAY 2417All SZGR genes in this pathway
SA_B_CELL_RECEPTOR_COMPLEXES 2420All SZGR genes in this pathway
ST_ERK1_ERK2_MAPK_PATHWAY 3225All SZGR genes in this pathway
ST_B_CELL_ANTIGEN_RECEPTOR 4032All SZGR genes in this pathway
SA_TRKA_RECEPTOR 1715All SZGR genes in this pathway
PID_FCER1_PATHWAY 6243All SZGR genes in this pathway
PID_ENDOTHELIN_PATHWAY 6352All SZGR genes in this pathway
PID_BCR_5PATHWAY 6550All SZGR genes in this pathway
PID_GMCSF_PATHWAY 3731All SZGR genes in this pathway
PID_MET_PATHWAY 8060All SZGR genes in this pathway
PID_EPHB_FWD_PATHWAY 4038All SZGR genes in this pathway
PID_SHP2_PATHWAY 5846All SZGR genes in this pathway
PID_NETRIN_PATHWAY 3227All SZGR genes in this pathway
PID_MTOR_4PATHWAY 6955All SZGR genes in this pathway
PID_IL2_1PATHWAY 5543All SZGR genes in this pathway
PID_TCR_RAS_PATHWAY 1414All SZGR genes in this pathway
PID_CERAMIDE_PATHWAY 4837All SZGR genes in this pathway
PID_IFNG_PATHWAY 4034All SZGR genes in this pathway
PID_ERBB1_DOWNSTREAM_PATHWAY 10578All SZGR genes in this pathway
PID_ERBB2_ERBB3_PATHWAY 4435All SZGR genes in this pathway
PID_FOXM1_PATHWAY 4030All SZGR genes in this pathway
PID_PDGFRB_PATHWAY 129103All SZGR genes in this pathway
PID_TRKR_PATHWAY 6248All SZGR genes in this pathway
PID_AR_NONGENOMIC_PATHWAY 3127All SZGR genes in this pathway
PID_HEDGEHOG_GLI_PATHWAY 4835All SZGR genes in this pathway
PID_CXCR3_PATHWAY 4334All SZGR genes in this pathway
PID_KIT_PATHWAY 5240All SZGR genes in this pathway
PID_VEGFR1_2_PATHWAY 6957All SZGR genes in this pathway
PID_ANTHRAX_PATHWAY 1715All SZGR genes in this pathway
PID_MAPK_TRK_PATHWAY 3431All SZGR genes in this pathway
PID_CD8_TCR_DOWNSTREAM_PATHWAY 6556All SZGR genes in this pathway
PID_FAK_PATHWAY 5945All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF 217167All SZGR genes in this pathway
REACTOME_SIGNALING_BY_SCF_KIT 7859All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_TRIF_MEDIATED_TLR3_SIGNALING 7454All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB4 9067All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB2 10178All SZGR genes in this pathway
REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING 2220All SZGR genes in this pathway
REACTOME_SIGNALING_BY_EGFR_IN_CANCER 10980All SZGR genes in this pathway
REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING 2017All SZGR genes in this pathway
REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE 8764All SZGR genes in this pathway
REACTOME_ARMS_MEDIATED_ACTIVATION 1717All SZGR genes in this pathway
REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS 1918All SZGR genes in this pathway
REACTOME_SIGNALLING_TO_RAS 2723All SZGR genes in this pathway
REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE 137105All SZGR genes in this pathway
REACTOME_SIGNALLING_TO_ERKS 3630All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 12788All SZGR genes in this pathway
REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN 1514All SZGR genes in this pathway
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 205136All SZGR genes in this pathway
REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING 1513All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_SIGNALING_BY_PDGF 12293All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION 9576All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH 6449All SZGR genes in this pathway
REACTOME_FRS2_MEDIATED_CASCADE 3627All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR 10074All SZGR genes in this pathway
REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE 5037All SZGR genes in this pathway
REACTOME_L1CAM_INTERACTIONS 8662All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ILS 10786All SZGR genes in this pathway
REACTOME_SIGNAL_TRANSDUCTION_BY_L1 3425All SZGR genes in this pathway
REACTOME_IL1_SIGNALING 3930All SZGR genes in this pathway
REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION 7757All SZGR genes in this pathway
REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE 7253All SZGR genes in this pathway
REACTOME_IL_2_SIGNALING 4134All SZGR genes in this pathway
REACTOME_SIGNALING_BY_INSULIN_RECEPTOR 10872All SZGR genes in this pathway
REACTOME_SOS_MEDIATED_SIGNALLING 1413All SZGR genes in this pathway
REACTOME_RAF_MAP_KINASE_CASCADE 1010All SZGR genes in this pathway
REACTOME_SHC_MEDIATED_SIGNALLING 1512All SZGR genes in this pathway
REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE 8363All SZGR genes in this pathway
REACTOME_INNATE_IMMUNE_SYSTEM 279178All SZGR genes in this pathway
REACTOME_ACTIVATED_TLR4_SIGNALLING 9369All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_TOLL_RECEPTOR_CASCADES 11884All SZGR genes in this pathway
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 270204All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR 11280All SZGR genes in this pathway
REACTOME_SHC_RELATED_EVENTS 1713All SZGR genes in this pathway
BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP 206111All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_UP 305185All SZGR genes in this pathway
BOGNI_TREATMENT_RELATED_MYELOID_LEUKEMIA_UP 3019All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP 11785All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN 483336All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_UP 10869All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
WEI_MIR34A_TARGETS 14897All SZGR genes in this pathway
MORI_MATURE_B_LYMPHOCYTE_UP 9062All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 151100All SZGR genes in this pathway
NEMETH_INFLAMMATORY_RESPONSE_LPS_UP 8864All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
KAAB_FAILED_HEART_ATRIUM_DN 14199All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR 544307All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
JI_RESPONSE_TO_FSH_DN 5843All SZGR genes in this pathway
ZHOU_TNF_SIGNALING_30MIN 5436All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_UP 198132All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_SCC_UP 12375All SZGR genes in this pathway
TRACEY_RESISTANCE_TO_IFNA2_DN 3223All SZGR genes in this pathway
JIANG_AGING_HYPOTHALAMUS_UP 4731All SZGR genes in this pathway
LEIN_NEURON_MARKERS 6945All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
FIRESTEIN_CTNNB1_PATHWAY 3323All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
YIH_RESPONSE_TO_ARSENITE_C5 107All SZGR genes in this pathway
SASSON_RESPONSE_TO_GONADOTROPHINS_UP 9159All SZGR genes in this pathway
SASSON_RESPONSE_TO_FORSKOLIN_UP 9058All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-15/16/195/424/4974634701A,m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-181728734m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-324-3p440446m8hsa-miR-324-3pCCACUGCCCCAGGUGCUGCUGG
miR-330458464m8hsa-miR-330brainGCAAAGCACACGGCCUGCAGAGA
miR-34/4495735801A,m8hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
miR-5034644701Ahsa-miR-503UAGCAGCGGGAACAGUUCUGCAG
miR-96131137m8hsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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