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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Gene Page: RHOA

Summary

GeneID

387

Symbol

RHOA

Synonyms

ARH12|ARHA|RHO12|RHOH12

Description

ras homolog gene family, member A

Locus tag

Gene type

protein-coding

Map location

3p21.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 2

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0603

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

H2AFY2

0.87

0.92

STAG1

0.86

0.89

PHF16

0.85

0.81

RNF122

0.85

0.72

LRCH2

0.84

0.92

KDM1

0.84

0.94

ZNF491

0.84

0.79

ZNF738

0.84

0.85

ZBTB5

0.84

0.90

PRIM1

0.84

0.85

Top 10 negatively co-expressed genes

HLA-F

-0.60

-0.84

TNFSF12

-0.59

-0.67

C5orf53

-0.59

-0.78

PTH1R

-0.58

-0.74

FBXO2

-0.58

-0.68

AIFM3

-0.58

-0.81

ALDOC

-0.58

-0.74

LHPP

-0.57

-0.64

LDHD

-0.56

-0.69

SLC9A3R2

-0.56

-0.57

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0000287

magnesium ion binding

IEA

GO:0003924

GTPase activity

TAS

10436159

GO:0005515

protein binding

IPI

15644318

GO:0005525

GTP binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007519

skeletal muscle development

IEA

neuron (GO term level: 8)

GO:0043524

negative regulation of neuron apoptosis

IEA

neuron (GO term level: 9)

GO:0000902

cell morphogenesis

IEA

GO:0007160

cell-matrix adhesion

IEA

GO:0007155

cell adhesion

IEA

GO:0007266

Rho protein signal transduction

TAS

10436159

GO:0007264

small GTPase mediated signal transduction

IEA

GO:0043149

stress fiber formation

IEA

GO:0042346

positive regulation of NF-kappaB import into nucleus

NAS

12761501

GO:0030154

cell differentiation

IEA

GO:0030036

actin cytoskeleton organization

TAS

10436159

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

IEP

12761501

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005829

cytosol

IEA

GO:0005856

cytoskeleton

IEA

GO:0005622

intracellular

IEA

GO:0005634

nucleus

IEA

GO:0005737

cytoplasm

IEA

GO:0005886

plasma membrane

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AKAP13	AKAP-Lbc \| BRX \| FLJ11952 \| FLJ43341 \| HA-3 \| Ht31 \| LBC \| PROTO-LB \| PROTO-LBC \| c-lbc	A kinase (PRKA) anchor protein 13	-	HPRD,BioGRID	11696353 \|12423633
ARHGAP1	CDC42GAP \| RHOGAP \| RHOGAP1 \| p50rhoGAP	Rho GTPase activating protein 1	-	HPRD,BioGRID	9407060 \|9548756
ARHGAP10	FLJ20896 \| FLJ41791 \| GRAF2 \| PS-GAP	Rho GTPase activating protein 10	Biochemical Activity	BioGRID	11432776
ARHGAP21	ARHGAP10 \| DKFZp761L0424 \| FLJ33323 \| FLJ90108	Rho GTPase activating protein 21	ARHGAP21 interacts with RhoA-GTP, and acts as a GAP to increase RhoA GTPase activity.	BIND	15793564
ARHGAP26	FLJ42530 \| GRAF \| KIAA0621 \| OPHN1L \| OPHN1L1	Rho GTPase activating protein 26	Biochemical Activity	BioGRID	11432776
ARHGAP5	GFI2 \| RhoGAP5 \| p190-B	Rho GTPase activating protein 5	Affinity Capture-Western Reconstituted Complex	BioGRID	12842009
ARHGAP8	BPGAP1 \| FLJ20185 \| PP610	Rho GTPase activating protein 8	BPGAP1 interacts with RhoA.	BIND	12944407
ARHGDIA	GDIA1 \| MGC117248 \| RHOGDI \| RHOGDI-1	Rho GDP dissociation inhibitor (GDI) alpha	-	HPRD,BioGRID	11149925
ARHGDIB	D4 \| GDIA2 \| GDID4 \| LYGDI \| Ly-GDI \| RAP1GN1 \| RhoGDI2	Rho GDP dissociation inhibitor (GDI) beta	-	HPRD,BioGRID	9799233
ARHGDIG	RHOGDI-3	Rho GDP dissociation inhibitor (GDI) gamma	-	HPRD,BioGRID	9113980
ARHGEF1	GEF1 \| LBCL2 \| LSC \| P115-RHOGEF \| SUB1.5	Rho guanine nucleotide exchange factor (GEF) 1	Biochemical Activity	BioGRID	12748184
ARHGEF11	DKFZp667F1223 \| GTRAP48 \| KIAA0380 \| PDZ-RHOGEF	Rho guanine nucleotide exchange factor (GEF) 11	-	HPRD,BioGRID	10526156
ARHGEF12	DKFZp686O2372 \| KIAA0382 \| LARG \| PRO2792	Rho guanine nucleotide exchange factor (GEF) 12	-	HPRD,BioGRID	11373293
ARHGEF18	KIAA0521 \| MGC15913	rho/rac guanine nucleotide exchange factor (GEF) 18	-	HPRD,BioGRID	11085924
ARHGEF2	DKFZp547L106 \| DKFZp547P1516 \| GEF \| GEF-H1 \| GEFH1 \| KIAA0651 \| LFP40 \| P40	rho/rac guanine nucleotide exchange factor (GEF) 2	-	HPRD,BioGRID	9857026
ARHGEF3	DKFZp434F2429 \| FLJ98126 \| GEF3 \| MGC118905 \| STA3 \| XPLN	Rho guanine nucleotide exchange factor (GEF) 3	-	HPRD,BioGRID	12221096
ARHGEF4	ASEF \| ASEF1 \| GEF4 \| STM6	Rho guanine nucleotide exchange factor (GEF) 4	-	HPRD,BioGRID	10947987
BID	FP497 \| MGC15319 \| MGC42355	BH3 interacting domain death agonist	Co-purification	BioGRID	15659383
CASP10	ALPS2 \| FLICE2 \| MCH4	caspase 10, apoptosis-related cysteine peptidase	Co-purification	BioGRID	15659383
CASP8	ALPS2B \| CAP4 \| FLICE \| FLJ17672 \| MACH \| MCH5 \| MGC78473	caspase 8, apoptosis-related cysteine peptidase	Co-purification	BioGRID	15659383
CIT	CRIK \| KIAA0949 \| STK21	citron (rho-interacting, serine/threonine kinase 21)	Far Western Reconstituted Complex Two-hybrid	BioGRID	8543060 \|12773565
CNKSR1	CNK \| CNK1 \| KSR	connector enhancer of kinase suppressor of Ras 1	-	HPRD	14749388
CNKSR1	CNK \| CNK1 \| KSR	connector enhancer of kinase suppressor of Ras 1	hCNK1 interacts with RhoA. This interaction was modelled on a demonstrated interaction between human CNK1 and RhoA from an unspecified species.	BIND	14749388
CNTNAP1	CASPR \| CNTNAP \| NRXN4 \| P190	contactin associated protein 1	-	HPRD	9407060
CRMP1	DPYSL1 \| DRP-1 \| DRP1	collapsin response mediator protein 1	Phenotypic Suppression	BioGRID	12482610
DAAM1	FLJ41657 \| KIAA0666	dishevelled associated activator of morphogenesis 1	-	HPRD	11779461
DEF6	IBP \| SLAT	differentially expressed in FDCP 6 homolog (mouse)	-	HPRD,BioGRID	15023524
DEF6	IBP \| SLAT	differentially expressed in FDCP 6 homolog (mouse)	DEF6 interacts with RhoA. This interaction was modelled on a demonstrated interaction between human DEF6 and RhoA from an unspecified species.	BIND	15023524
DGKQ	DAGK \| DAGK4 \| DAGK7	diacylglycerol kinase, theta 110kDa	-	HPRD,BioGRID	10066731
DIAPH1	DFNA1 \| DIA1 \| DRF1 \| FLJ25265 \| LFHL1 \| hDIA1	diaphanous homolog 1 (Drosophila)	Reconstituted Complex Two-hybrid	BioGRID	12773565
DOCK7	KIAA1771 \| ZIR2	dedicator of cytokinesis 7	-	HPRD	12432077
DPYSL2	CRMP2 \| DHPRP2 \| DRP-2 \| DRP2	dihydropyrimidinase-like 2	Phenotypic Suppression	BioGRID	12482610
EZR	CVIL \| CVL \| DKFZp762H157 \| FLJ26216 \| MGC1584 \| VIL2	ezrin	Co-purification	BioGRID	15659383
FADD	GIG3 \| MGC8528 \| MORT1	Fas (TNFRSF6)-associated via death domain	Co-purification	BioGRID	15659383
FAS	ALPS1A \| APO-1 \| APT1 \| CD95 \| FAS1 \| FASTM \| TNFRSF6	Fas (TNF receptor superfamily, member 6)	Co-purification	BioGRID	15659383
FASLG	APT1LG1 \| CD178 \| CD95L \| FASL \| TNFSF6	Fas ligand (TNF superfamily, member 6)	Co-purification	BioGRID	15659383
FLNA	ABP-280 \| ABPX \| DKFZp434P031 \| FLN \| FLN1 \| FMD \| MNS \| NHBP \| OPD \| OPD1 \| OPD2	filamin A, alpha (actin binding protein 280)	-	HPRD	10051605
GEFT	p63RhoGEF	RhoA/RAC/CDC42 exchange factor	-	HPRD,BioGRID	15069594
GMIP	-	GEM interacting protein	-	HPRD	12093360
GNA12	MGC104623 \| MGC99644 \| NNX3 \| RMP \| gep	guanine nucleotide binding protein (G protein) alpha 12	Reconstituted Complex	BioGRID	12515866
GRLF1	GRF-1 \| KIAA1722 \| MGC10745 \| P190-A \| P190A \| p190RhoGAP	glucocorticoid receptor DNA binding factor 1	Reconstituted Complex	BioGRID	9548756
HSPA1A	FLJ54303 \| FLJ54370 \| FLJ54392 \| FLJ54408 \| FLJ75127 \| HSP70-1 \| HSP70-1A \| HSP70I \| HSP72 \| HSPA1 \| HSPA1B	heat shock 70kDa protein 1A	Affinity Capture-Western	BioGRID	12490434
ICMT	HSTE14 \| MGC39955 \| MST098 \| MSTP098 \| PCCMT \| PCMT \| PPMT	isoprenylcysteine carboxyl methyltransferase	-	HPRD,BioGRID	9614111
ITPR1	INSP3R1 \| IP3R \| IP3R1 \| SCA15 \| SCA16	inositol 1,4,5-triphosphate receptor, type 1	Affinity Capture-Western Reconstituted Complex	BioGRID	12766172
KCNA2	HBK5 \| HK4 \| HUKIV \| KV1.2 \| MGC50217 \| MK2 \| NGK1 \| RBK2	potassium voltage-gated channel, shaker-related subfamily, member 2	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	9635436
KTN1	CG1 \| KIAA0004 \| KNT \| MGC133337 \| MU-RMS-40.19	kinectin 1 (kinesin receptor)	-	HPRD	8769096 \|11689693
KTN1	CG1 \| KIAA0004 \| KNT \| MGC133337 \| MU-RMS-40.19	kinectin 1 (kinesin receptor)	Two-hybrid	BioGRID	8769096 \|11162552 \|11689693 \|12773565
MAPK8	JNK \| JNK1 \| JNK1A2 \| JNK21B1/2 \| PRKM8 \| SAPK1	mitogen-activated protein kinase 8	Co-purification	BioGRID	15659383
MCF2	DBL	MCF.2 cell line derived transforming sequence	-	HPRD,BioGRID	10854437
MCF2L	ARHGEF14 \| DBS \| FLJ12122 \| KIAA0362 \| OST	MCF.2 cell line derived transforming sequence-like	RhoA specifically interacts with Dbl-homology and pleckstrin-homology domains of the nucleotide exchange factor Dbs. This interaction is modelled on a demonstrated interaction between mouse Dbs and human RhoA.	BIND	12006984
MCF2L	ARHGEF14 \| DBS \| FLJ12122 \| KIAA0362 \| OST	MCF.2 cell line derived transforming sequence-like	-	HPRD,BioGRID	12006984
MPRIP	KIAA0864 \| M-RIP \| RHOIP3 \| p116Rip	myosin phosphatase Rho interacting protein	-	HPRD	14506264
MPRIP	KIAA0864 \| M-RIP \| RHOIP3 \| p116Rip	myosin phosphatase Rho interacting protein	-	HPRD,BioGRID	9199174
MSN	-	moesin	Co-purification	BioGRID	15659383
NET1	ARHGEF8 \| NET1A	neuroepithelial cell transforming 1	Two-hybrid	BioGRID	9535835
OPHN1	MRX60 \| OPN1	oligophrenin 1	-	HPRD,BioGRID	9582072 \|11998687
PDE6D	PDED	phosphodiesterase 6D, cGMP-specific, rod, delta	-	HPRD,BioGRID	11786539
PITPNM1	DRES9 \| FLJ44997 \| NIR2 \| PITPNM \| RDGB \| RDGB1 \| RDGBA \| RDGBA1 \| Rd9	phosphatidylinositol transfer protein, membrane-associated 1	Nir2 interacts with RhoA.	BIND	15125835
PKN1	DBK \| MGC46204 \| PAK1 \| PKN \| PKN-ALPHA \| PRK1 \| PRKCL1	protein kinase N1	-	HPRD,BioGRID	9446575
PKN2	MGC150606 \| MGC71074 \| PAK2 \| PRK2 \| PRKCL2 \| PRO2042 \| Pak-2	protein kinase N2	-	HPRD,BioGRID	8910519
PLCG1	PLC-II \| PLC1 \| PLC148 \| PLCgamma1	phospholipase C, gamma 1	-	HPRD,BioGRID	12071848
PLD1	-	phospholipase D1, phosphatidylcholine-specific	-	HPRD,BioGRID	11311142 \|12593858
PLEKHG2	CLG \| DKFZp667J2325 \| FLJ00018 \| FLJ22458 \| FLJ38638	pleckstrin homology domain containing, family G (with RhoGef domain) member 2	-	HPRD,BioGRID	11839748
PPP1R12A	MBS \| MGC133042 \| MYPT1	protein phosphatase 1, regulatory (inhibitor) subunit 12A	-	HPRD	9354661
PRKCA	AAG6 \| MGC129900 \| MGC129901 \| PKC-alpha \| PKCA \| PRKACA	protein kinase C, alpha	in vivo	BioGRID	11284700
RABAC1	PRA1 \| PRAF1 \| YIP3	Rab acceptor 1 (prenylated)	-	HPRD	11335720
RAP1GDS1	GDS1 \| MGC118859 \| MGC118861 \| SmgGDS	RAP1, GTP-GDP dissociation stimulator 1	-	HPRD,BioGRID	11948427
RHPN1	KIAA1929 \| ODF5 \| RHOPHILIN \| RHPN	rhophilin, Rho GTPase binding protein 1	-	HPRD	12221077
RHPN2	RhoBP \| p76RBE	rhophilin, Rho GTPase binding protein 2	-	HPRD	12221077
RHPN2	RhoBP \| p76RBE	rhophilin, Rho GTPase binding protein 2	Two-hybrid	BioGRID	12773565
RICS	GC-GAP \| GRIT \| KIAA0712 \| MGC1892 \| p200RhoGAP \| p250GAP	Rho GTPase-activating protein	Biochemical Activity	BioGRID	12446789 \|12454018 \|12857875
RIPK4	ANKK2 \| ANKRD3 \| DIK \| MGC129992 \| MGC129993 \| PKK \| RIP4	receptor-interacting serine-threonine kinase 4	Two-hybrid	BioGRID	9199174
ROCK1	MGC131603 \| MGC43611 \| P160ROCK \| PRO0435	Rho-associated, coiled-coil containing protein kinase 1	-	HPRD,BioGRID	8798490
ROCK2	KIAA0619	Rho-associated, coiled-coil containing protein kinase 2	Affinity Capture-Western	BioGRID	11350930
RTKN	-	rhotekin	RhoA interacts with RTKN (Rhotekin). This interaction was modeled on a demonstrated interaction between RhoA and RTKN from an unspecified species.	BIND	15652748
			Rhotekin interacts with RhoA-GTP. This interaction was modeled on a demonstrated interaction between Rhotekin from an unspecified species and human Rho-GTP.	BIND	15467718
			-	HPRD	8662891
			RTKN (rhotekin) interacts with RhoA. This interaction was modeled on a demonstrated interaction between mouse RTKN and human RhoA.	BIND	15766663
			Reconstituted Complex	BioGRID	12593858
			RhoA interacts with Rhotekin. This interaction was modeled on a demonstrated interaction between human RhoA and Rhotekin from an unspecified species.	BIND	15834426
			Active, GTP-bound RhoA interacts with the RTKN (Rhotekin) Rho binding domain. This interaction was modelled on a demonstrated interaction between human RhoA and Rhotekin from an unspecified species.	BIND	15889147
SH3BP1	-	SH3-domain binding protein 1	-	HPRD	9548756
SPRED2	FLJ21897 \| FLJ31917 \| MGC163164 \| Spred-2	sprouty-related, EVH1 domain containing 2	-	HPRD	15184877
SRGAP1	ARHGAP13 \| FLJ22166 \| KIAA1304	SLIT-ROBO Rho GTPase activating protein 1	-	HPRD	11672528
TEC	MGC126760 \| MGC126762 \| PSCTK4	tec protein tyrosine kinase	Reconstituted Complex	BioGRID	12515866
TGM2	G-ALPHA-h \| GNAH \| TG2 \| TGC	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	-	HPRD	11350930
TNFRSF10B	CD262 \| DR5 \| KILLER \| KILLER/DR5 \| TRAIL-R2 \| TRAILR2 \| TRICK2 \| TRICK2A \| TRICK2B \| TRICKB \| ZTNFR9	tumor necrosis factor receptor superfamily, member 10b	Co-purification	BioGRID	15659383
TNFRSF1A	CD120a \| FPF \| MGC19588 \| TBP1 \| TNF-R \| TNF-R-I \| TNF-R55 \| TNFAR \| TNFR1 \| TNFR55 \| TNFR60 \| p55 \| p55-R \| p60	tumor necrosis factor receptor superfamily, member 1A	Co-purification	BioGRID	15659383
TRIO	FLJ42780 \| tgat	triple functional domain (PTPRF interacting)	-	HPRD,BioGRID	10948190
TRPC1	HTRP-1 \| MGC133334 \| MGC133335 \| TRP1	transient receptor potential cation channel, subfamily C, member 1	-	HPRD,BioGRID	12766172
VAV2	-	vav 2 guanine nucleotide exchange factor	-	HPRD	11909943
VAV3	FLJ40431	vav 3 guanine nucleotide exchange factor	-	HPRD,BioGRID	10523675

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_CHEMOKINE_SIGNALING_PATHWAY	190	128	All SZGR genes in this pathway
KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	115	81	All SZGR genes in this pathway
KEGG_WNT_SIGNALING_PATHWAY	151	112	All SZGR genes in this pathway
KEGG_TGF_BETA_SIGNALING_PATHWAY	86	64	All SZGR genes in this pathway
KEGG_AXON_GUIDANCE	129	103	All SZGR genes in this pathway
KEGG_FOCAL_ADHESION	201	138	All SZGR genes in this pathway
KEGG_ADHERENS_JUNCTION	75	53	All SZGR genes in this pathway
KEGG_TIGHT_JUNCTION	134	86	All SZGR genes in this pathway
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY	108	89	All SZGR genes in this pathway
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION	118	78	All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY	126	103	All SZGR genes in this pathway
KEGG_REGULATION_OF_ACTIN_CYTOSKELETON	216	144	All SZGR genes in this pathway
KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION	59	36	All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER	328	259	All SZGR genes in this pathway
KEGG_COLORECTAL_CANCER	62	47	All SZGR genes in this pathway
BIOCARTA_CCR3_PATHWAY	23	21	All SZGR genes in this pathway
BIOCARTA_ECM_PATHWAY	24	17	All SZGR genes in this pathway
BIOCARTA_RACCYCD_PATHWAY	26	23	All SZGR genes in this pathway
BIOCARTA_INTEGRIN_PATHWAY	38	29	All SZGR genes in this pathway
BIOCARTA_EDG1_PATHWAY	27	24	All SZGR genes in this pathway
BIOCARTA_AKAPCENTROSOME_PATHWAY	15	14	All SZGR genes in this pathway
BIOCARTA_RAS_PATHWAY	23	20	All SZGR genes in this pathway
BIOCARTA_RHO_PATHWAY	32	23	All SZGR genes in this pathway
BIOCARTA_AKAP13_PATHWAY	12	11	All SZGR genes in this pathway
BIOCARTA_CARDIACEGF_PATHWAY	18	16	All SZGR genes in this pathway
BIOCARTA_MAL_PATHWAY	19	17	All SZGR genes in this pathway
BIOCARTA_CDC42RAC_PATHWAY	16	13	All SZGR genes in this pathway
BIOCARTA_PAR1_PATHWAY	37	28	All SZGR genes in this pathway
BIOCARTA_TFF_PATHWAY	21	15	All SZGR genes in this pathway
BIOCARTA_UCALPAIN_PATHWAY	18	11	All SZGR genes in this pathway
SA_TRKA_RECEPTOR	17	15	All SZGR genes in this pathway
PID_ENDOTHELIN_PATHWAY	63	52	All SZGR genes in this pathway
PID_PRL_SIGNALING_EVENTS_PATHWAY	23	17	All SZGR genes in this pathway
PID_RHOA_PATHWAY	45	33	All SZGR genes in this pathway
PID_AURORA_B_PATHWAY	39	24	All SZGR genes in this pathway
PID_LYSOPHOSPHOLIPID_PATHWAY	66	53	All SZGR genes in this pathway
PID_WNT_NONCANONICAL_PATHWAY	32	26	All SZGR genes in this pathway
PID_ER_NONGENOMIC_PATHWAY	41	35	All SZGR genes in this pathway
PID_MET_PATHWAY	80	60	All SZGR genes in this pathway
PID_PTP1B_PATHWAY	52	40	All SZGR genes in this pathway
PID_S1P_S1P3_PATHWAY	29	24	All SZGR genes in this pathway
PID_AVB3_OPN_PATHWAY	31	29	All SZGR genes in this pathway
PID_S1P_S1P4_PATHWAY	14	11	All SZGR genes in this pathway
PID_RHOA_REG_PATHWAY	46	30	All SZGR genes in this pathway
PID_RET_PATHWAY	39	29	All SZGR genes in this pathway
PID_TXA2PATHWAY	57	43	All SZGR genes in this pathway
PID_SHP2_PATHWAY	58	46	All SZGR genes in this pathway
PID_S1P_S1P1_PATHWAY	21	18	All SZGR genes in this pathway
PID_NETRIN_PATHWAY	32	27	All SZGR genes in this pathway
PID_ARF6_DOWNSTREAM_PATHWAY	15	14	All SZGR genes in this pathway
PID_MTOR_4PATHWAY	69	55	All SZGR genes in this pathway
PID_IL2_1PATHWAY	55	43	All SZGR genes in this pathway
PID_CXCR4_PATHWAY	102	78	All SZGR genes in this pathway
PID_PLK1_PATHWAY	46	25	All SZGR genes in this pathway
PID_THROMBIN_PAR4_PATHWAY	15	11	All SZGR genes in this pathway
PID_PI3KCI_PATHWAY	49	40	All SZGR genes in this pathway
PID_P75_NTR_PATHWAY	69	51	All SZGR genes in this pathway
PID_ECADHERIN_NASCENT_AJ_PATHWAY	39	33	All SZGR genes in this pathway
PID_AMB2_NEUTROPHILS_PATHWAY	41	32	All SZGR genes in this pathway
PID_AVB3_INTEGRIN_PATHWAY	75	53	All SZGR genes in this pathway
PID_LIS1_PATHWAY	28	22	All SZGR genes in this pathway
PID_SYNDECAN_4_PATHWAY	32	25	All SZGR genes in this pathway
PID_EPHA_FWDPATHWAY	34	29	All SZGR genes in this pathway
PID_ECADHERIN_KERATINOCYTE_PATHWAY	21	19	All SZGR genes in this pathway
PID_PDGFRB_PATHWAY	129	103	All SZGR genes in this pathway
PID_TRKR_PATHWAY	62	48	All SZGR genes in this pathway
PID_ECADHERIN_STABILIZATION_PATHWAY	42	34	All SZGR genes in this pathway
PID_VEGFR1_2_PATHWAY	69	57	All SZGR genes in this pathway
PID_THROMBIN_PAR1_PATHWAY	43	32	All SZGR genes in this pathway
PID_SYNDECAN_2_PATHWAY	33	27	All SZGR genes in this pathway
PID_TOLL_ENDOGENOUS_PATHWAY	25	19	All SZGR genes in this pathway
PID_NCADHERIN_PATHWAY	33	32	All SZGR genes in this pathway
PID_S1P_S1P2_PATHWAY	24	19	All SZGR genes in this pathway
PID_EPHA2_FWD_PATHWAY	19	16	All SZGR genes in this pathway
PID_FAK_PATHWAY	59	45	All SZGR genes in this pathway
PID_TGFBR_PATHWAY	55	38	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_RHO_GTPASES	113	81	All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF	217	167	All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY	396	292	All SZGR genes in this pathway
REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE	137	105	All SZGR genes in this pathway
REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	16	7	All SZGR genes in this pathway
REACTOME_PI3K_AKT_ACTIVATION	38	29	All SZGR genes in this pathway
REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	81	61	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR	920	449	All SZGR genes in this pathway
REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE	31	25	All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE	251	188	All SZGR genes in this pathway
REACTOME_G_ALPHA1213_SIGNALLING_EVENTS	74	56	All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING	805	368	All SZGR genes in this pathway
REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	32	22	All SZGR genes in this pathway
REACTOME_SEMAPHORIN_INTERACTIONS	68	53	All SZGR genes in this pathway
REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	27	21	All SZGR genes in this pathway
REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	25	15	All SZGR genes in this pathway
REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	28	18	All SZGR genes in this pathway
REACTOME_HEMOSTASIS	466	331	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	63	42	All SZGR genes in this pathway
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	208	138	All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN	526	357	All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP	423	283	All SZGR genes in this pathway
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN	362	238	All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN	153	100	All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN	800	473	All SZGR genes in this pathway
LI_LUNG_CANCER	41	30	All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP	358	245	All SZGR genes in this pathway
ALCALA_APOPTOSIS	88	60	All SZGR genes in this pathway
LOPEZ_MBD_TARGETS	957	597	All SZGR genes in this pathway
RICKMAN_METASTASIS_DN	261	155	All SZGR genes in this pathway
ZUCCHI_METASTASIS_DN	44	29	All SZGR genes in this pathway
IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_DN	21	14	All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	555	346	All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_DN	408	274	All SZGR genes in this pathway
ZAMORA_NOS2_TARGETS_UP	69	41	All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR	544	307	All SZGR genes in this pathway
CHIBA_RESPONSE_TO_TSA	50	31	All SZGR genes in this pathway
MACLACHLAN_BRCA1_TARGETS_UP	21	16	All SZGR genes in this pathway
ZHANG_PROLIFERATING_VS_QUIESCENT	51	41	All SZGR genes in this pathway
DELLA_RESPONSE_TO_TSA_AND_BUTYRATE	21	17	All SZGR genes in this pathway
VERRECCHIA_EARLY_RESPONSE_TO_TGFB1	58	43	All SZGR genes in this pathway
RAMPON_ENRICHED_LEARNING_ENVIRONMENT_EARLY_UP	15	12	All SZGR genes in this pathway
VERRECCHIA_RESPONSE_TO_TGFB1_C3	14	10	All SZGR genes in this pathway
JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP	31	21	All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST	132	93	All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5	482	296	All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED	1022	619	All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED	1229	713	All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN	940	425	All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES	389	245	All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN	193	112	All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION	422	277	All SZGR genes in this pathway
YAGI_AML_WITH_T_9_11_TRANSLOCATION	130	87	All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1	237	159	All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP	756	494	All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP	682	440	All SZGR genes in this pathway
ABDELMOHSEN_ELAVL4_TARGETS	16	13	All SZGR genes in this pathway
HOLLEMAN_DAUNORUBICIN_B_ALL_DN	12	10	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-142-5p	330	337	1A,m8	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-185	987	994	1A,m8	hsa-miR-185^brain	UGGAGAGAAAGGCAGUUC
miR-200bc/429	133	139	m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-361	742	749	1A,m8	hsa-miR-361^brain	UUAUCAGAAUCUCCAGGGGUAC
miR-381	614	620	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-485-3p	62	68	m8	hsa-miR-485-3p	GUCAUACACGGCUCUCCUCUCU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.