Gene Page: PTPN11

Summary
GeneID  5781
Symbol  PTPN11
Synonyms  BPTP3|CFC|MGC14433|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2
Description  protein tyrosine phosphatase, non-receptor type 11
See related  HGNC:9644|MIM:176876|Ensembl:ENSG00000179295|HPRD:01470|
Locus tag  -
Gene type  protein-coding
Map location  12q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.9666 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
OTUD7A0.880.82
TACC10.870.82
ZMAT30.850.80
MBNL10.840.80
KIAA16710.830.79
CHIC10.830.80
RAPGEF50.830.73
NR3C10.820.77
FAM120A0.820.82
MBNL20.820.78
Top 10 negatively co-expressed genes
EXOSC8-0.47-0.53
SNHG12-0.47-0.62
RPL27-0.46-0.56
C9orf46-0.46-0.54
ST20-0.45-0.54
RPL35-0.45-0.54
PFDN5-0.44-0.52
RPL31-0.44-0.55
RPS13P2-0.44-0.54
RPS23-0.44-0.55
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI9658397 |9792637 |10209036 
GO:0004726non-membrane spanning protein tyrosine phosphatase activityEXP10734310 |14560030 |14665621 
|15574420 
GO:0004726non-membrane spanning protein tyrosine phosphatase activityTAS7681589 
GO:0016787hydrolase activityIEA-
GO:0051428peptide hormone receptor bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007409axonogenesisIEAneuron, axon, neurite (GO term level: 12)-
GO:0000077DNA damage checkpointIEA-
GO:0000187activation of MAPK activityIEA-
GO:0009967positive regulation of signal transductionIEA-
GO:0006470protein amino acid dephosphorylationIEA-
GO:0009755hormone-mediated signalingIEA-
GO:0007605sensory perception of soundIEA-
GO:0048011nerve growth factor receptor signaling pathwayIEA-
GO:0006641triacylglycerol metabolic processIEA-
GO:0006629lipid metabolic processIEA-
GO:0042593glucose homeostasisIEA-
GO:0042445hormone metabolic processIEA-
GO:0035265organ growthIEA-
GO:0040014regulation of multicellular organism growthIEA-
GO:0046887positive regulation of hormone secretionIEA-
GO:0046676negative regulation of insulin secretionIEA-
GO:0046825regulation of protein export from nucleusIEA-
GO:0048609reproductive process in a multicellular organismIEA-
GO:0060125negative regulation of growth hormone secretionIEA-
GO:0051463negative regulation of cortisol secretionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP9054388 |10734310 |14560030 
|14665621 |15574420 
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BCAR1CAS | CAS1 | CASS1 | CRKAS | P130Casbreast cancer anti-estrogen resistance 1Affinity Capture-WesternBioGRID9188452 
BCRALL | BCR-ABL1 | BCR1 | CML | D22S11 | D22S662 | FLJ16453 | PHLbreakpoint cluster regionPhosphorylated p210bcr-abl interacts with phosphorylated Syp. This interaction was modeled on a demonstrated interaction between human p210bcr-abl and mouse Syp.BIND8195176 
-HPRD12115002 
BDKRB2B2R | BK-2 | BK2 | BKR2 | BRB2 | DKFZp686O088bradykinin receptor B2-HPRD12177051 
BTLABTLA1 | CD272 | FLJ16065 | MGC129743B and T lymphocyte associated-HPRD,BioGRID12796776 
C6orf25G6b | MGC142279 | MGC142281 | NG31chromosome 6 open reading frame 25-HPRD,BioGRID11544253 
CATMGC138422 | MGC138424catalaseCat interacts with Shp-2.BIND15556604 
CAV1CAV | MSTP085 | VIP21caveolin 1, caveolae protein, 22kDa-HPRD,BioGRID12176037 
caveolin-1 interacts with SH-PTP2.BIND12176037 
CD33FLJ00391 | SIGLEC-3 | SIGLEC3 | p67CD33 molecule-HPRD,BioGRID10206955 
CD84DKFZp781E2378 | LY9B | SLAMF5 | hCD84 | mCD84CD84 moleculeAffinity Capture-WesternBioGRID11689425 
CDH57B4 | CD144 | FLJ17376cadherin 5, type 2 (vascular endothelium)-HPRD,BioGRID10681592 
CEACAM1BGP | BGP1 | BGPIcarcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)-HPRD,BioGRID9867848 |12108545 
CRKL-v-crk sarcoma virus CT10 oncogene homolog (avian)-like-HPRD,BioGRID9344843 
CSF2RBCD131 | CDw131 | IL3RB | IL5RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)-HPRD,BioGRID9162089 
CSF3RCD114 | GCSFRcolony stimulating factor 3 receptor (granulocyte)-HPRD,BioGRID9824671 
CTLA4CD152 | CELIAC3 | CTLA-4 | GSE | IDDM12cytotoxic T-lymphocyte-associated protein 4-HPRD,BioGRID8638161 
CTNNB1CTNNB | DKFZp686D02253 | FLJ25606 | FLJ37923catenin (cadherin-associated protein), beta 1, 88kDaAffinity Capture-WesternBioGRID10681592 
EGFRERBB | ERBB1 | HER1 | PIG61 | mENAepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)-HPRD,BioGRID7673163 
EPHA2ECKEPH receptor A2Affinity Capture-WesternBioGRID10655584 
EPORMGC138358erythropoietin receptor-HPRD,BioGRID8639815 
ERBB2CD340 | HER-2 | HER-2/neu | HER2 | NEU | NGL | TKR1v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)Affinity Capture-MSBioGRID16729043 
ERBB4HER4 | MGC138404 | p180erbB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)Affinity Capture-MSBioGRID16729043 
FCRL3FCRH3 | IFGP3 | IRTA3 | SPAP2Fc receptor-like 3Reconstituted ComplexBioGRID12051764 
FLT1FLT | VEGFR1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)Flt-1 interacts with the amino terminal SH2 domain of SHP-2.BIND9600074 
FRS2FRS2A | FRS2alpha | SNT | SNT-1 | SNT1fibroblast growth factor receptor substrate 2-HPRD9632781 |11447289 
-HPRD,BioGRID9632781 
FRS3FRS2B | FRS2beta | MGC17167 | SNT-2 | SNT2fibroblast growth factor receptor substrate 3-HPRD11432792 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YES-HPRD,BioGRID10212213 
GAB1-GRB2-associated binding protein 1SHP2 interacts with and dephosphorylates Gab1.BIND12582165 
-HPRD,BioGRID11940581 
GAB2KIAA0571GRB2-associated binding protein 2-HPRD10068651 |11287610 
Affinity Capture-Western
Two-hybrid
BioGRID10391903 |11334882 
|11782427 |12135708 
GAB3-GRB2-associated binding protein 3-HPRD,BioGRID11739737 
GHRGHBPgrowth hormone receptor-HPRD,BioGRID10976913 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2Affinity Capture-Western
Far Western
Reconstituted Complex
BioGRID8041791 |8702859 
|8995399 |9362449 
|9632781 |9824671 
|10080542 |10212213 
|10747947 
-HPRD8041791 |8702859 
|12531430 
Grb2 interacts with Syp via Syp SH2 domains.BIND7523381 |8195176 
IFNAR1AVP | IFN-alpha-REC | IFNAR | IFNBR | IFRCinterferon (alpha, beta and omega) receptor 1-HPRD9029147 
IGF1RCD221 | IGFIR | JTK13 | MGC142170 | MGC142172 | MGC18216insulin-like growth factor 1 receptor-HPRD,BioGRID7642582 
IL4RCD124 | IL4RAinterleukin 4 receptor-HPRD,BioGRID11714803 
IL6STCD130 | CDw130 | GP130 | GP130-RAPS | IL6R-betainterleukin 6 signal transducer (gp130, oncostatin M receptor)-HPRD,BioGRID10946280 
-HPRD9195977 
INPP5DMGC104855 | MGC142140 | MGC142142 | SHIP | SHIP1 | SIP-145 | hp51CNinositol polyphosphate-5-phosphatase, 145kDaAffinity Capture-WesternBioGRID9110989 
INSRCD220 | HHF5insulin receptor-HPRD,BioGRID7493946 |8135823 
IRS1HIRS-1insulin receptor substrate 1-HPRD,BioGRID8505282 |9756938 
IRS2-insulin receptor substrate 2-HPRD,BioGRID8910607 
IRS4IRS-4 | PY160insulin receptor substrate 4-HPRD12774026 
JAK1JAK1A | JAK1B | JTK3Janus kinase 1 (a protein tyrosine kinase)-HPRD,BioGRID8995399 |11036942 
|12403768 
JAK2JTK10Janus kinase 2 (a protein tyrosine kinase)Biochemical Activity
in vivo
Reconstituted Complex
BioGRID8639815 |8912646 
|8995399 
-HPRD7559603 |8912646 
|8995399 
KITC-Kit | CD117 | PBT | SCFRv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog-HPRD,BioGRID7523381 |9528781 
Syp interacts with c-Kit via its SH2 domain.BIND7523381 
KLRC1CD159A | MGC13374 | MGC59791 | NKG2 | NKG2Akiller cell lectin-like receptor subfamily C, member 1-HPRD9485206 
LAIR1CD305 | LAIR-1leukocyte-associated immunoglobulin-like receptor 1-HPRD,BioGRID9285412 
LCKYT16 | p56lck | pp58lcklymphocyte-specific protein tyrosine kinase-HPRD10617656 
LEPRCD295 | OBRleptin receptor-HPRD11018044 
LIFRCD118 | FLJ98106 | FLJ99923 | LIF-R | SJS2 | STWS | SWSleukemia inhibitory factor receptor alpha-HPRD,BioGRID10800945 
LILRB4CD85K | HM18 | ILT3 | LILRB5 | LIR-5 | LIR5leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4-HPRD9422771 
Protein-peptideBioGRID9973385 
LY9CD229 | SLAMF3 | hly9 | mLY9lymphocyte antigen 9Affinity Capture-WesternBioGRID11689425 
METAUTS9 | HGFR | RCCP2 | c-Metmet proto-oncogene (hepatocyte growth factor receptor)-HPRD8662733 
MPZL1FLJ21047 | PZR | PZR1b | PZRa | PZRbmyelin protein zero-like 1-HPRD,BioGRID9792637 
NEDD9CAS-L | CAS2 | CASL | CASS2 | HEF1 | dJ49G10.2 | dJ761I2.1neural precursor cell expressed, developmentally down-regulated 9-HPRD8879209 
PAG1CBP | FLJ37858 | MGC138364 | PAGphosphoprotein associated with glycosphingolipid microdomains 1-HPRD10790433 
PDGFRBCD140B | JTK12 | PDGF-R-beta | PDGFR | PDGFR1platelet-derived growth factor receptor, beta polypeptideReconstituted Complex
Two-hybrid
BioGRID7691811 |11266449 
PDGFR interacts with Syp.BIND7688466 
Autophosphorylated PDGFR interacts with Syp. This interaction was modelled on a demonstrated interaction between human PDGFR and Syp from an unspecified species.BIND8890167 
PECAM1CD31 | PECAM-1platelet/endothelial cell adhesion moleculeAffinity Capture-Western
Far Western
Reconstituted Complex
BioGRID9054388 |9774457 
|10350061 |10801826 
PIK3R1GRB1 | p85 | p85-ALPHAphosphoinositide-3-kinase, regulatory subunit 1 (alpha)Affinity Capture-WesternBioGRID9918857 
PILRAFDF03paired immunoglobin-like type 2 receptor alpha-HPRD10660620 
Affinity Capture-WesternBioGRID10903717 
PLCG2-phospholipase C, gamma 2 (phosphatidylinositol-specific)Affinity Capture-WesternBioGRID12135708 
PRLRhPRLrIprolactin receptorAffinity Capture-WesternBioGRID10991949 
PTK2FADK | FAK | FAK1 | pp125FAKPTK2 protein tyrosine kinase 2-HPRD,BioGRID7589239 |8986614 
|10082579 |10655584 
PTK2BCADTK | CAKB | FADK2 | FAK2 | FRNK | PKB | PTK | PYK2 | RAFTKPTK2B protein tyrosine kinase 2 beta-HPRD,BioGRID10880513 
PXNFLJ16691paxillin-HPRD8986614 |10082579 
|10655584 
ROS1MCF3 | ROS | c-ros-1c-ros oncogene 1 , receptor tyrosine kinaseTwo-hybridBioGRID11266449 
SELECD62E | ELAM | ELAM1 | ESEL | LECAM2selectin E-HPRD,BioGRID11602579 
SHC1FLJ26504 | SHC | SHCASHC (Src homology 2 domain containing) transforming protein 1-HPRD10650943 
SIGLEC11-sialic acid binding Ig-like lectin 11-HPRD,BioGRID11986327 
SIGLEC12FLJ38600 | S2V | SIGLECL1 | SLG | Siglec-12 | Siglec-L1 | Siglec-XIIsialic acid binding Ig-like lectin 12-HPRD11328818 
SIGLEC7AIRM1 | CD328 | CDw328 | D-siglec | QA79 | SIGLEC-7 | p75 | p75/AIRM1sialic acid binding Ig-like lectin 7-HPRD10499918 
SIT1MGC125908 | MGC125909 | MGC125910 | RP11-331F9.5 | SITsignaling threshold regulating transmembrane adaptor 1-HPRD,BioGRID10209036 |11433379 
|11491537 
SLAMF1CD150 | CDw150 | SLAMsignaling lymphocytic activation molecule family member 1-HPRD,BioGRID11806999 
CD150 interacts with SHP-2. This interaction was modelled on a demonstrated interaction between human CD150 and monkey SHP-2.BIND11477068 
SLAMF6KALI | KALIb | Ly108 | MGC104953 | NTB-A | NTBA | SF2000SLAM family member 6-HPRD,BioGRID11489943 
SOCS3ATOD4 | CIS3 | Cish3 | MGC71791 | SOCS-3 | SSI-3 | SSI3suppressor of cytokine signaling 3Affinity Capture-Western
Reconstituted Complex
BioGRID12403768 
SOS1GF1 | GGF1 | GINGF | HGF | NS4son of sevenless homolog 1 (Drosophila)Affinity Capture-WesternBioGRID9344843 |9632781 
STAT3APRF | FLJ20882 | HIES | MGC16063signal transducer and activator of transcription 3 (acute-phase response factor)-HPRD,BioGRID11594781 
STAT5AMGF | STAT5signal transducer and activator of transcription 5A-HPRD,BioGRID12060651 
STAT5BSTAT5signal transducer and activator of transcription 5BBiochemical Activity
Reconstituted Complex
BioGRID10617656 
SYNCRIPGRY-RBP | HNRPQ1 | NSAP1 | RP1-3J17.2 | dJ3J17.2 | hnRNP-Q | pp68synaptotagmin binding, cytoplasmic RNA interacting proteinTwo-hybridBioGRID9847309 
TEKCD202B | TIE-2 | TIE2 | VMCM | VMCM1TEK tyrosine kinase, endothelial-HPRD10521483 
TIE1JTK14 | TIEtyrosine kinase with immunoglobulin-like and EGF-like domains 1-HPRD10949653 
TNFRSF1ACD120a | FPF | MGC19588 | TBP1 | TNF-R | TNF-R-I | TNF-R55 | TNFAR | TNFR1 | TNFR55 | TNFR60 | p55 | p55-R | p60tumor necrosis factor receptor superfamily, member 1A-HPRD11786908 
TREML1GLTL1825 | MGC119173 | PRO3438 | TLT-1 | TLT1 | dJ238O23.3triggering receptor expressed on myeloid cells-like 1-HPRD,BioGRID15128762 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_JAK_STAT_SIGNALING_PATHWAY 155105All SZGR genes in this pathway
KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 13792All SZGR genes in this pathway
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 11878All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 126103All SZGR genes in this pathway
KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 6757All SZGR genes in this pathway
KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION 6844All SZGR genes in this pathway
KEGG_RENAL_CELL_CARCINOMA 7060All SZGR genes in this pathway
KEGG_CHRONIC_MYELOID_LEUKEMIA 7359All SZGR genes in this pathway
BIOCARTA_IGF1_PATHWAY 2116All SZGR genes in this pathway
BIOCARTA_IL6_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_INSULIN_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_MET_PATHWAY 3730All SZGR genes in this pathway
BIOCARTA_CTLA4_PATHWAY 2118All SZGR genes in this pathway
ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS 4535All SZGR genes in this pathway
PID_FCER1_PATHWAY 6243All SZGR genes in this pathway
PID_INSULIN_PATHWAY 4532All SZGR genes in this pathway
PID_GMCSF_PATHWAY 3731All SZGR genes in this pathway
PID_TCR_PATHWAY 6651All SZGR genes in this pathway
PID_MET_PATHWAY 8060All SZGR genes in this pathway
PID_RET_PATHWAY 3929All SZGR genes in this pathway
PID_ANGIOPOIETIN_RECEPTOR_PATHWAY 5041All SZGR genes in this pathway
PID_SHP2_PATHWAY 5846All SZGR genes in this pathway
PID_IL2_1PATHWAY 5543All SZGR genes in this pathway
PID_CXCR4_PATHWAY 10278All SZGR genes in this pathway
PID_IGF1_PATHWAY 3023All SZGR genes in this pathway
PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY 3529All SZGR genes in this pathway
PID_IL5_PATHWAY 1411All SZGR genes in this pathway
PID_IL2_PI3K_PATHWAY 3427All SZGR genes in this pathway
PID_AVB3_INTEGRIN_PATHWAY 7553All SZGR genes in this pathway
PID_IFNG_PATHWAY 4034All SZGR genes in this pathway
PID_ERBB2_ERBB3_PATHWAY 4435All SZGR genes in this pathway
PID_IL3_PATHWAY 2719All SZGR genes in this pathway
PID_IL6_7_PATHWAY 4740All SZGR genes in this pathway
PID_PDGFRB_PATHWAY 129103All SZGR genes in this pathway
PID_TRKR_PATHWAY 6248All SZGR genes in this pathway
PID_VEGFR1_PATHWAY 2623All SZGR genes in this pathway
PID_KIT_PATHWAY 5240All SZGR genes in this pathway
PID_EPO_PATHWAY 3429All SZGR genes in this pathway
PID_IL2_STAT5_PATHWAY 3023All SZGR genes in this pathway
PID_VEGFR1_2_PATHWAY 6957All SZGR genes in this pathway
PID_NCADHERIN_PATHWAY 3332All SZGR genes in this pathway
PID_FGF_PATHWAY 5537All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
HOEBEKE_LYMPHOID_STEM_CELL_DN 8659All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP 276165All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_UP 341197All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_UP 457269All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_DN 209122All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP 309199All SZGR genes in this pathway
TSAI_RESPONSE_TO_IONIZING_RADIATION 149101All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_DN 411249All SZGR genes in this pathway
AMIT_EGF_RESPONSE_60_HELA 4632All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP 424268All SZGR genes in this pathway
DER_IFN_BETA_RESPONSE_UP 10267All SZGR genes in this pathway
BROCKE_APOPTOSIS_REVERSED_BY_IL6 14498All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 151100All SZGR genes in this pathway
MA_MYELOID_DIFFERENTIATION_UP 3929All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_UP 240152All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_16HR_UP 225139All SZGR genes in this pathway
ZHENG_RESPONSE_TO_ARSENITE_DN 1815All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_8HR_UP 10573All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_DN 228146All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP 393244All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_DN 220147All SZGR genes in this pathway
OUYANG_PROSTATE_CANCER_PROGRESSION_DN 2116All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_DN 249165All SZGR genes in this pathway
GRESHOCK_CANCER_COPY_NUMBER_UP 323240All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
BRUNEAU_SEPTATION_VENTRICULAR 108All SZGR genes in this pathway
BRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS 88All SZGR genes in this pathway
WANG_RECURRENT_LIVER_CANCER_UP 2013All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_1HR_UP 6144All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_UP 5541All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP 12170All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124/50617521758m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-138227722841A,m8hsa-miR-138brainAGCUGGUGUUGUGAAUC
miR-200bc/429373937451Ahsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-496382438311A,m8hsa-miR-496AUUACAUGGCCAAUCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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