Gene Page: AKT1

Summary
GeneID  207
Symbol  AKT1
Synonyms  AKT|MGC99656|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA
Description  v-akt murine thymoma viral oncogene homolog 1
See related  HGNC:391|MIM:164730|Ensembl:ENSG00000142208|HPRD:01261|
Locus tag  -
Gene type  protein-coding
Map location  14q32.32|14q32.32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 31.3585 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MAN2A20.860.84
IPO130.860.82
ABCA20.850.83
SLC6A80.830.84
FAM102A0.820.77
SEMA4D0.820.81
ANGEL10.820.81
NIPAL30.810.81
KLHL210.810.80
TMEM1890.800.77
Top 10 negatively co-expressed genes
SNRPG-0.49-0.63
C9orf46-0.49-0.55
FAM36A-0.48-0.50
RPL31-0.46-0.55
RPL13AP22-0.45-0.67
SPINK8-0.45-0.52
RPL35-0.45-0.55
RPL24-0.45-0.53
RPL35A-0.45-0.57
TBCA-0.44-0.46
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0030235nitric-oxide synthase regulator activityIMP10376603 
GO:0005351sugar:hydrogen symporter activityIEA-
GO:0005524ATP bindingIC11994271 
GO:0004674protein serine/threonine kinase activityEXP9829964 |10490848 |11274386 
GO:0004674protein serine/threonine kinase activityIDA11994271 |16139227 
GO:0016740transferase activityIEA-
GO:0042802identical protein bindingIPI7891724 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000060protein import into nucleus, translocationIMP16280327 
GO:0001568blood vessel developmentIEA-
GO:0001890placenta developmentIEA-
GO:0006417regulation of translationIEA-
GO:0007186G-protein coupled receptor protein signaling pathwayTAS10570282 
GO:0006464protein modification processTAS10570282 
GO:0007242intracellular signaling cascadeIDA14749367 
GO:0007281germ cell developmentIEA-
GO:0006006glucose metabolic processIEA-
GO:0005978glycogen biosynthetic processIEA-
GO:0005975carbohydrate metabolic processIEA-
GO:0008286insulin receptor signaling pathwayIMP8978681 
GO:0008633activation of pro-apoptotic gene productsEXP15231831 
GO:0008637apoptotic mitochondrial changesIEA-
GO:0008643carbohydrate transportIEA-
GO:0009408response to heatTAS10958679 
GO:0009725response to hormone stimulusIEA-
GO:0015758glucose transportIEA-
GO:0048009insulin-like growth factor receptor signaling pathwayIMP8978681 
GO:0006954inflammatory responseIEA-
GO:0006924activated T cell apoptosisIMP14749367 
GO:0016567protein ubiquitinationIEA-
GO:0018105peptidyl-serine phosphorylationIDA16139227 
GO:0051000positive regulation of nitric-oxide synthase activityIMP10376603 
GO:0040018positive regulation of multicellular organism growthIEA-
GO:0034405response to fluid shear stressIMP10376603 
GO:0030163protein catabolic processIEA-
GO:0043491protein kinase B signaling cascadeIEA-
GO:0042640anagenIEA-
GO:0045884regulation of survival gene product expressionIEA-
GO:0046777protein amino acid autophosphorylationTAS16280327 
GO:0045429positive regulation of nitric oxide biosynthetic processIMP10376603 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005819spindleIEA-
GO:0005829cytosolEXP9381178 |9812896 |10485710 
|10698680 |11715018 
|12167717 |12244303 
|12524439 |15183529 
|15718470 
GO:0005856cytoskeletonIDA18029348 
GO:0005634nucleusIEA-
GO:0005654nucleoplasmEXP9829964 |10490848 |11274386 
GO:0005737cytoplasmISS-
GO:0030027lamellipodiumIEA-
GO:0005886plasma membraneEXP10698680 |15808505 
GO:0005886plasma membraneIDA14749367 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AKTIPFT1 | FTSAKT interacting protein-HPRD,BioGRID14749367 
APPL1APPL | DIP13alphaadaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1APPL interacts with Akt1.BIND10490823 
ARAIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFMandrogen receptorAkt phosphorylates AR.BIND11404460 |12621049 
Affinity Capture-Western
Reconstituted Complex		BioGRID11404460 
ARFIP2POR1ADP-ribosylation factor interacting protein 2Two-hybridBioGRID9312003 
ARHGAP29PARG1 | RP11-255E17.1Rho GTPase activating protein 29Two-hybridBioGRID14749388 
BADBBC2 | BCL2L8BCL2-associated agonist of cell deathReconstituted ComplexBioGRID11500364 
BRAFB-RAF1 | BRAF1 | FLJ95109 | MGC126806 | MGC138284 | RAFB1v-raf murine sarcoma viral oncogene homolog B1-HPRD,BioGRID10869359 
BRCA1BRCAI | BRCC1 | IRIS | PSCP | RNF53breast cancer 1, early onsetReconstituted ComplexBioGRID10542266 
CARHSP1CRHSP-24 | CSDC1 | MGC111446calcium regulated heat stable protein 1, 24kDaReconstituted ComplexBioGRID15910284 
CDKN1BCDKN4 | KIP1 | MEN1B | MEN4 | P27KIP1cyclin-dependent kinase inhibitor 1B (p27, Kip1)Affinity Capture-Western
Biochemical Activity		BioGRID12042314 
CHN2ARHGAP3 | BCH | MGC138360 | RHOGAP3chimerin (chimaerin) 2Reconstituted ComplexBioGRID11278894 
CHUKIKBKA | IKK-alpha | IKK1 | IKKA | NFKBIKA | TCF16conserved helix-loop-helix ubiquitous kinase-HPRD,BioGRID10485710 
CSNK2A1CK2A1 | CKIIcasein kinase 2, alpha 1 polypeptideCK2 interacts with and phosphorylates Akt. This interaction was modeled on a demonstrated interaction between human CK2 and Akt from an unspecified species and mouse.BIND15818404 
FANCAFA | FA-H | FA1 | FAA | FACA | FAH | FANCH | MGC75158Fanconi anemia, complementation group ATwo-hybridBioGRID14499622 
FOXO4AFX | AFX1 | MGC120490 | MLLT7forkhead box O4-HPRD11313479 
AKT1 interacts with MLLT7 (FOXO4). This interaction was modelled on a demonstrated interaction between human AKT1 and FOXO4 from an unspecified species.BIND15688030 
FRAP1FLJ44809 | FRAP | FRAP2 | MTOR | RAFT1 | RAPT1FK506 binding protein 12-rapamycin associated protein 1Protein-peptide
Reconstituted Complex		BioGRID10910062 |14970221 
|15718470 
GAB2KIAA0571GRB2-associated binding protein 2-HPRD,BioGRID11782427 
GRB10GRB-IR | Grb-10 | IRBP | KIAA0207 | MEG1 | RSSgrowth factor receptor-bound protein 10-HPRD11809791 
GSK3B-glycogen synthase kinase 3 betaAKT1 interacts with and phosphorylates GSK3B. This interaction was modelled on a demonstrated interaction between human AKT1 and GSK3B from an unspecified species.BIND15688030 
Reconstituted ComplexBioGRID16009706 
HSP90AA1FLJ31884 | HSP86 | HSP89A | HSP90A | HSP90N | HSPC1 | HSPCA | HSPCAL1 | HSPCAL4 | HSPN | Hsp89 | Hsp90 | LAP2heat shock protein 90kDa alpha (cytosolic), class A member 1-HPRD,BioGRID10995457 
HSP90AB1D6S182 | FLJ26984 | HSP90-BETA | HSP90B | HSPC2 | HSPCBheat shock protein 90kDa alpha (cytosolic), class B member 1Affinity Capture-WesternBioGRID10995457 
HSPB1CMT2F | DKFZp586P1322 | HMN2B | HS.76067 | HSP27 | HSP28 | Hsp25 | SRP27heat shock 27kDa protein 1Affinity Capture-WesternBioGRID11042204 
HTTHD | IT15huntingtinHuntingtin is serine-phosphorylated by Akt.BIND12062094 
ILKDKFZp686F1765 | P59integrin-linked kinase-HPRD,BioGRID9736715 
IMPDH2IMPD2 | IMPDH-IIIMP (inosine monophosphate) dehydrogenase 2The pleckstrin homology domain of PKB/Akt-alpha interacts with IMPDH type II.BIND10930578 
-HPRD,BioGRID10930578 
IRAK1IRAK | pelleinterleukin-1 receptor-associated kinase 1-HPRD,BioGRID11976320 
IRS1HIRS-1insulin receptor substrate 1-HPRD,BioGRID10497255 
KRT10CK10 | K10 | KPPkeratin 10-HPRD,BioGRID11585925 
KTN1CG1 | KIAA0004 | KNT | MGC133337 | MU-RMS-40.19kinectin 1 (kinesin receptor)Two-hybridBioGRID11162552 
MAP2K4JNKK | JNKK1 | MAPKK4 | MEK4 | MKK4 | PRKMK4 | SEK1 | SERK1mitogen-activated protein kinase kinase 4-HPRD,BioGRID11707464 
MAP3K11MGC17114 | MLK-3 | MLK3 | PTK1 | SPRKmitogen-activated protein kinase kinase kinase 11-HPRD,BioGRID12458207 
MAP3K8COT | EST | ESTF | FLJ10486 | TPL2 | Tpl-2 | c-COTmitogen-activated protein kinase kinase kinase 8-HPRD,BioGRID12138205 
MAPK14CSBP1 | CSBP2 | CSPB1 | EXIP | Mxi2 | PRKM14 | PRKM15 | RK | SAPK2A | p38 | p38ALPHAmitogen-activated protein kinase 14Affinity Capture-Western
Biochemical Activity		BioGRID11042204 
MAPK8IP1IB1 | JIP-1 | JIP1 | PRKM8IPmitogen-activated protein kinase 8 interacting protein 1-HPRD,BioGRID12194869 
MAPKAP1JC310 | MGC2745 | MIP1 | SIN1 | SIN1b | SIN1gmitogen-activated protein kinase associated protein 1Affinity Capture-WesternBioGRID16962653 
MAPKAPK2MK2mitogen-activated protein kinase-activated protein kinase 2-HPRD,BioGRID11042204 
MDM2HDMX | MGC71221 | hdm2Mdm2 p53 binding protein homolog (mouse)HDM2 interacts with and is phosphorylated by Akt.BIND11960368 
METTL1C12orf1 | FLJ95748 | TRM8 | YDL201wmethyltransferase like 1Mettl1 interacts with and is phosphorylated by PKB-alpha (Akt)BIND15861136 
MTCP1C6.1Bmature T-cell proliferation 1-HPRD,BioGRID11707444 
NCF1CSH3PXD1Cneutrophil cytosolic factor 1C pseudogeneAkt interaction with and phosphorylation of p47-phoxBIND12734380 
NR4A1GFRP1 | HMR | MGC9485 | N10 | NAK-1 | NGFIB | NP10 | NUR77 | TR3nuclear receptor subfamily 4, group A, member 1-HPRD,BioGRID11274386 
PAK1MGC130000 | MGC130001 | PAKalphap21 protein (Cdc42/Rac)-activated kinase 1Reconstituted ComplexBioGRID14749719 
PAK6PAK5p21 protein (Cdc42/Rac)-activated kinase 6Reconstituted ComplexBioGRID11773441 
PDK1-pyruvate dehydrogenase kinase, isozyme 1PDK1 interacts with and phosphorylates Akt1. This interaction was modeled on a demonstrated interaction between PDK1 and Akt1, both from unspecified species.BIND15678105 
PDPK1MGC20087 | MGC35290 | PDK1 | PRO04613-phosphoinositide dependent protein kinase-1-HPRD,BioGRID11825911 
PDK1 phosphorylates Akt1.BIND15718470 
PEA15HMAT1 | HUMMAT1H | MAT1 | MAT1H | PEA-15 | PEDphosphoprotein enriched in astrocytes 15Akt interacts with PED.BIND12808093 
PHLPPMGC161555 | PHLPP1 | PLEKHE1 | SCOPPH domain and leucine rich repeat protein phosphatasePHLPP interacts with Akt. This interaction was modelled on a demonstrated interaction between human PHLPP and Akt from an unspecified species.BIND15808505 
PIAS2MGC102682 | MIZ1 | PIASX | PIASX-ALPHA | PIASX-BETA | SIZ2 | ZMIZ4 | mizprotein inhibitor of activated STAT, 2Miz1 interacts with Akt.BIND15580267 
PKN2MGC150606 | MGC71074 | PAK2 | PRK2 | PRKCL2 | PRO2042 | Pak-2protein kinase N2-HPRD,BioGRID10926925 
PLXNA1NOV | NOVP | PLEXIN-A1 | PLXN1plexin A1-HPRD,BioGRID15187088 
PRKCQMGC126514 | MGC141919 | PRKCT | nPKC-thetaprotein kinase C, theta-HPRD,BioGRID11410591 
PRKCZPKC-ZETA | PKC2protein kinase C, zeta-HPRD,BioGRID10085094 
PRKDCDNA-PKcs | DNAPK | DNPK1 | HYRC | HYRC1 | XRCC7 | p350protein kinase, DNA-activated, catalytic polypeptideDNA-PKcs interacts with Akt1.BIND15678105 
PTPN1PTP1Bprotein tyrosine phosphatase, non-receptor type 1-HPRD11579209 
RAF1CRAF | NS5 | Raf-1 | c-Rafv-raf-1 murine leukemia viral oncogene homolog 1-HPRD,BioGRID10576742 
RICSGC-GAP | GRIT | KIAA0712 | MGC1892 | p200RhoGAP | p250GAPRho GTPase-activating proteinBiochemical ActivityBioGRID12446789 
RICTORDKFZp686B11164 | KIAA1999 | MGC39830 | mAVO3rapamycin-insensitive companion of mTORReconstituted ComplexBioGRID15718470 
RPS6KB1PS6K | S6K | S6K1 | STK14A | p70(S6K)-alpha | p70-S6K | p70-alpharibosomal protein S6 kinase, 70kDa, polypeptide 1-HPRD11438723 
Co-purificationBioGRID15149849 
SMAD2JV18 | JV18-1 | MADH2 | MADR2 | MGC22139 | MGC34440 | hMAD-2 | hSMAD2SMAD family member 2Affinity Capture-WesternBioGRID16362038 
SMAD3DKFZp586N0721 | DKFZp686J10186 | HSPC193 | HsT17436 | JV15-2 | MADH3 | MGC60396SMAD family member 3Affinity Capture-WesternBioGRID16362038 
SMAD4DPC4 | JIP | MADH4SMAD family member 4Affinity Capture-WesternBioGRID16362038 
SMAD7CRCS3 | FLJ16482 | MADH7 | MADH8SMAD family member 7Affinity Capture-WesternBioGRID16362038 
TCL1ATCL1T-cell leukemia/lymphoma 1A-HPRD10983986 |12009899 
Affinity Capture-Western
Reconstituted Complex		BioGRID10983986 |11707444 
|12009899 
TCL1 interacts with AKT1.BIND11707444 
TCL1BTML1T-cell leukemia/lymphoma 1B-HPRD,BioGRID10983986 
TCL1B interacts with AKT1.BIND11707444 
TERTEST2 | TCS1 | TP2 | TRT | hEST2telomerase reverse transcriptaseAffinity Capture-WesternBioGRID15843522 
THEM4CTMP | MGC29636thioesterase superfamily member 4-HPRD,BioGRID11598301 
TNFSF11CD254 | ODF | OPGL | OPTB2 | RANKL | TRANCE | hRANKL2 | sOdftumor necrosis factor (ligand) superfamily, member 11-HPRD10635328 
TRIB3C20orf97 | NIPK | SINK | SKIP3 | TRB3tribbles homolog 3 (Drosophila)Affinity Capture-Western
Reconstituted Complex		BioGRID12791994 
TSC1KIAA0243 | LAM | MGC86987 | TSCtuberous sclerosis 1-HPRD,BioGRID12167664 
TSC2FLJ43106 | LAM | TSC4tuberous sclerosis 2-HPRD,BioGRID12167664 
Akt interacts with and phosphorylates tuberin. This interaction was modelled on a demonstrated interaction between Akt from an unspecified species and human Tuberin.BIND12150915 
UXS1FLJ23591 | UGDUDP-glucuronate decarboxylase 1-HPRD11877387 
YBX1BP-8 | CSDA2 | CSDB | DBPB | MDR-NF1 | MGC104858 | MGC110976 | MGC117250 | NSEP-1 | NSEP1 | YB-1 | YB1Y box binding protein 1Akt-1 interacts with and phosphorylates YB-1.BIND15806160 
YWHAZKCIP-1 | MGC111427 | MGC126532 | MGC138156tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide-HPRD,BioGRID11956222 
Akt interaction with and phosphorylation of 14-3-3 zeta at the same residue as MAPKAPK2.BIND11956222 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_MAPK_SIGNALING_PATHWAY 267205All SZGR genes in this pathway
KEGG_ERBB_SIGNALING_PATHWAY 8771All SZGR genes in this pathway
KEGG_CHEMOKINE_SIGNALING_PATHWAY 190128All SZGR genes in this pathway
KEGG_MTOR_SIGNALING_PATHWAY 5240All SZGR genes in this pathway
KEGG_APOPTOSIS 8862All SZGR genes in this pathway
KEGG_VEGF_SIGNALING_PATHWAY 7653All SZGR genes in this pathway
KEGG_FOCAL_ADHESION 201138All SZGR genes in this pathway
KEGG_TIGHT_JUNCTION 13486All SZGR genes in this pathway
KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY 10288All SZGR genes in this pathway
KEGG_JAK_STAT_SIGNALING_PATHWAY 155105All SZGR genes in this pathway
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 10889All SZGR genes in this pathway
KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 7556All SZGR genes in this pathway
KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY 7958All SZGR genes in this pathway
KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 9771All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 126103All SZGR genes in this pathway
KEGG_INSULIN_SIGNALING_PATHWAY 137103All SZGR genes in this pathway
KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION 8659All SZGR genes in this pathway
KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 6757All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_COLORECTAL_CANCER 6247All SZGR genes in this pathway
KEGG_RENAL_CELL_CARCINOMA 7060All SZGR genes in this pathway
KEGG_PANCREATIC_CANCER 7056All SZGR genes in this pathway
KEGG_ENDOMETRIAL_CANCER 5245All SZGR genes in this pathway
KEGG_GLIOMA 6556All SZGR genes in this pathway
KEGG_PROSTATE_CANCER 8975All SZGR genes in this pathway
KEGG_MELANOMA 7157All SZGR genes in this pathway
KEGG_CHRONIC_MYELOID_LEUKEMIA 7359All SZGR genes in this pathway
KEGG_ACUTE_MYELOID_LEUKEMIA 6047All SZGR genes in this pathway
KEGG_SMALL_CELL_LUNG_CANCER 8467All SZGR genes in this pathway
KEGG_NON_SMALL_CELL_LUNG_CANCER 5447All SZGR genes in this pathway
BIOCARTA_NO1_PATHWAY 3324All SZGR genes in this pathway
BIOCARTA_AKT_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_CHEMICAL_PATHWAY 2215All SZGR genes in this pathway
BIOCARTA_BCELLSURVIVAL_PATHWAY 1610All SZGR genes in this pathway
BIOCARTA_HDAC_PATHWAY 3225All SZGR genes in this pathway
BIOCARTA_GCR_PATHWAY 2217All SZGR genes in this pathway
BIOCARTA_HCMV_PATHWAY 1716All SZGR genes in this pathway
BIOCARTA_P53HYPOXIA_PATHWAY 2321All SZGR genes in this pathway
BIOCARTA_IL4_PATHWAY 118All SZGR genes in this pathway
BIOCARTA_IL2RB_PATHWAY 3826All SZGR genes in this pathway
BIOCARTA_GSK3_PATHWAY 2726All SZGR genes in this pathway
BIOCARTA_RACCYCD_PATHWAY 2623All SZGR genes in this pathway
BIOCARTA_GLEEVEC_PATHWAY 2317All SZGR genes in this pathway
BIOCARTA_MTOR_PATHWAY 2315All SZGR genes in this pathway
BIOCARTA_IGF1R_PATHWAY 2320All SZGR genes in this pathway
BIOCARTA_NFAT_PATHWAY 5645All SZGR genes in this pathway
BIOCARTA_PTDINS_PATHWAY 2316All SZGR genes in this pathway
BIOCARTA_EDG1_PATHWAY 2724All SZGR genes in this pathway
BIOCARTA_PTEN_PATHWAY 1814All SZGR genes in this pathway
BIOCARTA_RAS_PATHWAY 2320All SZGR genes in this pathway
BIOCARTA_BAD_PATHWAY 2623All SZGR genes in this pathway
BIOCARTA_EIF4_PATHWAY 2419All SZGR genes in this pathway
BIOCARTA_ERK5_PATHWAY 1815All SZGR genes in this pathway
BIOCARTA_ACH_PATHWAY 1613All SZGR genes in this pathway
BIOCARTA_IGF1MTOR_PATHWAY 2014All SZGR genes in this pathway
BIOCARTA_TEL_PATHWAY 1815All SZGR genes in this pathway
BIOCARTA_LONGEVITY_PATHWAY 1513All SZGR genes in this pathway
BIOCARTA_CREB_PATHWAY 2725All SZGR genes in this pathway
BIOCARTA_TFF_PATHWAY 2115All SZGR genes in this pathway
BIOCARTA_TRKA_PATHWAY 1210All SZGR genes in this pathway
ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS 4535All SZGR genes in this pathway
SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES 6754All SZGR genes in this pathway
ST_G_ALPHA_I_PATHWAY 3529All SZGR genes in this pathway
SIG_CHEMOTAXIS 4537All SZGR genes in this pathway
ST_P38_MAPK_PATHWAY 3728All SZGR genes in this pathway
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES 2723All SZGR genes in this pathway
SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES 3525All SZGR genes in this pathway
ST_ADRENERGIC 3629All SZGR genes in this pathway
ST_INTEGRIN_SIGNALING_PATHWAY 8262All SZGR genes in this pathway
ST_GAQ_PATHWAY 2822All SZGR genes in this pathway
ST_GA13_PATHWAY 3732All SZGR genes in this pathway
SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES 5141All SZGR genes in this pathway
SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES 3631All SZGR genes in this pathway
SIG_BCR_SIGNALING_PATHWAY 4638All SZGR genes in this pathway
ST_B_CELL_ANTIGEN_RECEPTOR 4032All SZGR genes in this pathway
ST_INTERLEUKIN_4_PATHWAY 2618All SZGR genes in this pathway
ST_WNT_BETA_CATENIN_PATHWAY 3428All SZGR genes in this pathway
ST_JNK_MAPK_PATHWAY 4030All SZGR genes in this pathway
ST_MYOCYTE_AD_PATHWAY 2725All SZGR genes in this pathway
SA_PTEN_PATHWAY 1714All SZGR genes in this pathway
SA_TRKA_RECEPTOR 1715All SZGR genes in this pathway
ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY 3729All SZGR genes in this pathway
PID_SMAD2_3NUCLEAR_PATHWAY 8263All SZGR genes in this pathway
PID_FCER1_PATHWAY 6243All SZGR genes in this pathway
PID_ENDOTHELIN_PATHWAY 6352All SZGR genes in this pathway
PID_BCR_5PATHWAY 6550All SZGR genes in this pathway
PID_LYSOPHOSPHOLIPID_PATHWAY 6653All SZGR genes in this pathway
PID_INSULIN_PATHWAY 4532All SZGR genes in this pathway
PID_IL4_2PATHWAY 6543All SZGR genes in this pathway
PID_TCR_PATHWAY 6651All SZGR genes in this pathway
PID_ER_NONGENOMIC_PATHWAY 4135All SZGR genes in this pathway
PID_CD40_PATHWAY 3126All SZGR genes in this pathway
PID_MET_PATHWAY 8060All SZGR genes in this pathway
PID_PTP1B_PATHWAY 5240All SZGR genes in this pathway
PID_S1P_S1P3_PATHWAY 2924All SZGR genes in this pathway
PID_AR_PATHWAY 6146All SZGR genes in this pathway
PID_REELIN_PATHWAY 2929All SZGR genes in this pathway
PID_ILK_PATHWAY 4532All SZGR genes in this pathway
PID_CD8_TCR_PATHWAY 5342All SZGR genes in this pathway
PID_ANGIOPOIETIN_RECEPTOR_PATHWAY 5041All SZGR genes in this pathway
PID_FAS_PATHWAY 3829All SZGR genes in this pathway
PID_TXA2PATHWAY 5743All SZGR genes in this pathway
PID_TELOMERASE_PATHWAY 6848All SZGR genes in this pathway
PID_HNF3B_PATHWAY 4537All SZGR genes in this pathway
PID_REG_GR_PATHWAY 8260All SZGR genes in this pathway
PID_MTOR_4PATHWAY 6955All SZGR genes in this pathway
PID_CXCR4_PATHWAY 10278All SZGR genes in this pathway
PID_IGF1_PATHWAY 3023All SZGR genes in this pathway
PID_FOXO_PATHWAY 4943All SZGR genes in this pathway
PID_IL2_PI3K_PATHWAY 3427All SZGR genes in this pathway
PID_CERAMIDE_PATHWAY 4837All SZGR genes in this pathway
PID_P75_NTR_PATHWAY 6951All SZGR genes in this pathway
PID_ECADHERIN_NASCENT_AJ_PATHWAY 3933All SZGR genes in this pathway
PID_AMB2_NEUTROPHILS_PATHWAY 4132All SZGR genes in this pathway
PID_AVB3_INTEGRIN_PATHWAY 7553All SZGR genes in this pathway
PID_IFNG_PATHWAY 4034All SZGR genes in this pathway
PID_ERBB1_DOWNSTREAM_PATHWAY 10578All SZGR genes in this pathway
PID_ERBB2_ERBB3_PATHWAY 4435All SZGR genes in this pathway
PID_IL6_7_PATHWAY 4740All SZGR genes in this pathway
PID_ECADHERIN_KERATINOCYTE_PATHWAY 2119All SZGR genes in this pathway
PID_NEPHRIN_NEPH1_PATHWAY 3124All SZGR genes in this pathway
PID_RETINOIC_ACID_PATHWAY 3023All SZGR genes in this pathway
PID_IL8_CXCR2_PATHWAY 3426All SZGR genes in this pathway
PID_HEDGEHOG_2PATHWAY 2217All SZGR genes in this pathway
PID_AR_NONGENOMIC_PATHWAY 3127All SZGR genes in this pathway
PID_HEDGEHOG_GLI_PATHWAY 4835All SZGR genes in this pathway
PID_CXCR3_PATHWAY 4334All SZGR genes in this pathway
PID_VEGFR1_PATHWAY 2623All SZGR genes in this pathway
PID_KIT_PATHWAY 5240All SZGR genes in this pathway
PID_VEGFR1_2_PATHWAY 6957All SZGR genes in this pathway
PID_A6B1_A6B4_INTEGRIN_PATHWAY 4635All SZGR genes in this pathway
PID_AURORA_A_PATHWAY 3120All SZGR genes in this pathway
PID_INSULIN_GLUCOSE_PATHWAY 2624All SZGR genes in this pathway
PID_PI3KCI_AKT_PATHWAY 3530All SZGR genes in this pathway
PID_IL8_CXCR1_PATHWAY 2819All SZGR genes in this pathway
PID_HIF1_TFPATHWAY 6652All SZGR genes in this pathway
PID_P53_REGULATION_PATHWAY 5950All SZGR genes in this pathway
PID_PI3K_PLC_TRK_PATHWAY 3631All SZGR genes in this pathway
PID_LYMPH_ANGIOGENESIS_PATHWAY 2516All SZGR genes in this pathway
PID_FGF_PATHWAY 5537All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF 217167All SZGR genes in this pathway
REACTOME_SIGNALING_BY_SCF_KIT 7859All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION 139All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB4 9067All SZGR genes in this pathway
REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING 129All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB2 10178All SZGR genes in this pathway
REACTOME_SIGNALING_BY_EGFR_IN_CANCER 10980All SZGR genes in this pathway
REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING 3828All SZGR genes in this pathway
REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING 4434All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 9766All SZGR genes in this pathway
REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 12690All SZGR genes in this pathway
REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE 137105All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 12788All SZGR genes in this pathway
REACTOME_ENOS_ACTIVATION_AND_REGULATION 2014All SZGR genes in this pathway
REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK 95All SZGR genes in this pathway
REACTOME_PI3K_AKT_ACTIVATION 3829All SZGR genes in this pathway
REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL 1210All SZGR genes in this pathway
REACTOME_GAB1_SIGNALOSOME 3829All SZGR genes in this pathway
REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS 7948All SZGR genes in this pathway
REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT 3023All SZGR genes in this pathway
REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS 2015All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING 2717All SZGR genes in this pathway
REACTOME_SIGNALING_BY_PDGF 12293All SZGR genes in this pathway
REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE 3125All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION 9576All SZGR genes in this pathway
REACTOME_CD28_CO_STIMULATION 3226All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA 2515All SZGR genes in this pathway
REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY 6348All SZGR genes in this pathway
REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING 2218All SZGR genes in this pathway
REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING 2818All SZGR genes in this pathway
REACTOME_CTLA4_INHIBITORY_SIGNALING 2115All SZGR genes in this pathway
REACTOME_METABOLISM_OF_MRNA 284128All SZGR genes in this pathway
REACTOME_METABOLISM_OF_RNA 330155All SZGR genes in this pathway
REACTOME_PI_3K_CASCADE 5639All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR 10074All SZGR genes in this pathway
REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 179All SZGR genes in this pathway
REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS 8450All SZGR genes in this pathway
REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP 179All SZGR genes in this pathway
REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION 3623All SZGR genes in this pathway
REACTOME_APOPTOSIS 14894All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS 1712All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM 539350All SZGR genes in this pathway
REACTOME_PIP3_ACTIVATES_AKT_SIGNALING 2920All SZGR genes in this pathway
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 208138All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR 11280All SZGR genes in this pathway
REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS 3021All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
WANG_LMO4_TARGETS_UP 372227All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_DN 406230All SZGR genes in this pathway
CREIGHTON_AKT1_SIGNALING_VIA_MTOR_UP 3422All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_DN 196131All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_UP 197135All SZGR genes in this pathway
MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP 169127All SZGR genes in this pathway
PUJANA_BREAST_CANCER_LIT_INT_NETWORK 10173All SZGR genes in this pathway
LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER 214139All SZGR genes in this pathway
COURTOIS_SENESCENCE_TRIGGERS 65All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_2 3023All SZGR genes in this pathway
SMITH_TERT_TARGETS_DN 8769All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN 225163All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
NATSUME_RESPONSE_TO_INTERFERON_BETA_UP 7149All SZGR genes in this pathway
JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_UP 4928All SZGR genes in this pathway
BILD_E2F3_ONCOGENIC_SIGNATURE 246153All SZGR genes in this pathway
HILLION_HMGA1_TARGETS 9071All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
FOURNIER_ACINAR_DEVELOPMENT_LATE_2 277172All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_DN 253192All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 181101All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN 315215All SZGR genes in this pathway
ZHANG_ADIPOGENESIS_BY_BMP7 1412All SZGR genes in this pathway


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