Gene Page: ABCB6

Summary
GeneID  10058
Symbol  ABCB6
Synonyms  ABC|ABC14|EST45597|FLJ22414|MTABC3|PRP|umat
Description  ATP-binding cassette, sub-family B (MDR/TAP), member 6
See related  HGNC:47|MIM:605452|Ensembl:ENSG00000115657|HPRD:09261|
Locus tag  -
Gene type  protein-coding
Map location  2q36
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00916 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01016 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PSMD80.880.87
NHP2L10.850.81
APEH0.830.80
UQCRC10.820.81
C19orf620.820.79
WDR450.820.79
COPS60.820.77
ARFIP20.810.78
C14orf1190.810.79
LSM40.810.79
Top 10 negatively co-expressed genes
AF347015.18-0.64-0.56
AF347015.26-0.60-0.50
AF347015.8-0.58-0.45
MT-ATP8-0.58-0.49
AC010300.1-0.57-0.59
AF347015.2-0.56-0.44
AF347015.21-0.56-0.45
AF347015.33-0.55-0.47
AF347015.15-0.54-0.44
AF347015.27-0.54-0.48
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005524ATP bindingIDA10837493 
GO:0016887ATPase activityIEA-
GO:0042626ATPase activity, coupled to transmembrane movement of substancesIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006810transportIDA10837493 
GO:0006879cellular iron ion homeostasisNAS11977179 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005739mitochondrionIDA10837493 
GO:0005740mitochondrial envelopeIDA10837493 
GO:0005741mitochondrial outer membraneIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0043190ATP-binding cassette (ABC) transporter complexNAS11955620 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ABC_TRANSPORTERS 4429All SZGR genes in this pathway
REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT 3421All SZGR genes in this pathway
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 413270All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP 309199All SZGR genes in this pathway
SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION 5031All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
MENSE_HYPOXIA_UP 9871All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_MATURE_CELL 293160All SZGR genes in this pathway
KAAB_FAILED_HEART_ATRIUM_DN 14199All SZGR genes in this pathway
SU_TESTIS 7653All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
GAJATE_RESPONSE_TO_TRABECTEDIN_DN 1911All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
KAAB_FAILED_HEART_VENTRICLE_DN 4128All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP 7747All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
WONG_MITOCHONDRIA_GENE_MODULE 217122All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN 353226All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_UP 210124All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
QI_HYPOXIA 14096All SZGR genes in this pathway
GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB 14583All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_DN 211119All SZGR genes in this pathway
BOUDOUKHA_BOUND_BY_IGF2BP2 11159All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-29941011A,m8hsa-miR-29aSZUAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZUAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZUAGCACCAUUUGAAAUCGGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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