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| GeneID |
10587
|
| Symbol |
TXNRD2
|
| Synonyms |
SELZ|TR|TR-BETA|TR3|TRXR2
|
| Description |
thioredoxin reductase 2 |
| See related |
HGNC:18155|MIM:606448|Ensembl:ENSG00000184470|HPRD:05921|HPRD:18519| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
22q11.21 |
|
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| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_I | genome scan meta-analysis | Psr: 0.031 | |
|
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| General Gene Expression (microarray) ? |
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| |
| Gene Expression in Brain Regions (new) |
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| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| CAPRIN2 | 0.82 | 0.78 | | |
| AC008443.1 | 0.78 | 0.74 | | |
| UGCGL2 | 0.77 | 0.64 | | |
| CCDC66 | 0.76 | 0.63 | | |
| TTC14 | 0.76 | 0.65 | | |
| PPWD1 | 0.75 | 0.71 | | |
| WSB1 | 0.75 | 0.64 | | |
| AC008806.1 | 0.74 | 0.81 | | |
| ZNF382 | 0.74 | 0.74 | | |
| SFRS5 | 0.74 | 0.73 | | |
Top 10 negatively co-expressed genes | | AF347015.31 | -0.52 | -0.56 | | |
| MT-CO2 | -0.51 | -0.54 | | |
| AF347015.21 | -0.50 | -0.55 | | |
| HIGD1B | -0.50 | -0.56 | | |
| AF347015.2 | -0.49 | -0.51 | | |
| AF347015.8 | -0.49 | -0.52 | | |
| MT-CYB | -0.49 | -0.51 | | |
| AF347015.33 | -0.48 | -0.49 | | |
| IFI27 | -0.48 | -0.54 | | |
| AF347015.27 | -0.48 | -0.51 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004791 | thioredoxin-disulfide reductase activity | ISS | | - |
| GO:0008430 | selenium binding | IEA | | - |
| GO:0016654 | oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor | IEA | | - |
| GO:0009055 | electron carrier activity | IEA | | - |
| GO:0016491 | oxidoreductase activity | IEA | | - |
| GO:0050660 | FAD binding | IEA | | - |
| GO:0050661 | NADP binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0000305 | response to oxygen radical | TAS | | 10455115 |
| GO:0045454 | cell redox homeostasis | IEA | | - |
| GO:0055114 | oxidation reduction | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005737 | cytoplasm | IEA | | - |
| GO:0005739 | mitochondrion | IDA | | 10215850 |
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