Gene Page: AHCYL1

Summary
GeneID  10768
Symbol  AHCYL1
Synonyms  DCAL|IRBIT|PRO0233|XPVKONA
Description  S-adenosylhomocysteine hydrolase-like 1
See related  HGNC:344|MIM:607826|Ensembl:ENSG00000168710|HPRD:07613|
Locus tag  -
Gene type  protein-coding
Map location  1p13.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SMC40.920.81
FBXO50.910.83
PLK40.910.80
SGOL20.900.83
KNTC10.900.81
ERCC6L0.900.74
CHEK10.890.79
C11orf820.890.81
FANCI0.890.76
TTK0.890.79
Top 10 negatively co-expressed genes
HLA-F-0.55-0.74
MT-CO2-0.55-0.80
AIFM3-0.54-0.75
AF347015.33-0.54-0.80
AF347015.31-0.54-0.78
AF347015.27-0.54-0.78
MT-CYB-0.54-0.81
SLC9A3R2-0.53-0.62
AF347015.15-0.53-0.81
TINAGL1-0.53-0.74
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003824catalytic activityIEA-
GO:0004013adenosylhomocysteinase activityIEA-
GO:0005488bindingIEA-
GO:0016787hydrolase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008152metabolic processIEA-
GO:0006730one-carbon compound metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005783endoplasmic reticulumIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ITPR1INSP3R1 | IP3R | IP3R1 | SCA15 | SCA16inositol 1,4,5-triphosphate receptor, type 1-HPRD,BioGRID12525476 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 3424All SZGR genes in this pathway
KEGG_SELENOAMINO_ACID_METABOLISM 2618All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP 10867All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
GARY_CD5_TARGETS_UP 473314All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_DN 406230All SZGR genes in this pathway
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP 233161All SZGR genes in this pathway
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN 362238All SZGR genes in this pathway
KIM_WT1_TARGETS_8HR_UP 164122All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_DN 196131All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_AUGMENTED_BY_MYC 10874All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
DORSAM_HOXA9_TARGETS_UP 3525All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_DN 12179All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_UP 8951All SZGR genes in this pathway
YAGI_AML_FAB_MARKERS 191131All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_NO_BLOOD_DN 15093All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_UP 388234All SZGR genes in this pathway
NICK_RESPONSE_TO_PROC_TREATMENT_DN 2718All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_UP 442263All SZGR genes in this pathway
OKAMOTO_LIVER_CANCER_MULTICENTRIC_OCCURRENCE_UP 2515All SZGR genes in this pathway
STEIN_ESRRA_TARGETS 535325All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.13623681Ahsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-13518841890m8hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
miR-137202320291Ahsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-1431291361A,m8hsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-182157915861A,m8hsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-249539591Ahsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
miR-25/32/92/363/367200020061Ahsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-320138213881Ahsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
miR-33199820041Ahsa-miR-33GUGCAUUGUAGUUGCAUUG
hsa-miR-33bGUGCAUUGCUGUUGCAUUGCA
miR-49618881894m8hsa-miR-496AUUACAUGGCCAAUCUC
miR-96158015861Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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