Gene Page: RPP40

Summary
GeneID  10799
Symbol  RPP40
Synonyms  RNASEP1|bA428J1.3
Description  ribonuclease P/MRP 40kDa subunit
See related  HGNC:20992|MIM:606117|Ensembl:ENSG00000124787|HPRD:09361|
Locus tag  -
Gene type  protein-coding
Map location  6p25.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0159 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NARG20.800.77
HAUS60.790.78
AQR0.790.77
TCF120.790.75
SMARCA50.790.75
DDX470.780.78
SOAT10.770.74
ZW100.770.76
SP30.770.73
NFATC30.770.72
Top 10 negatively co-expressed genes
MT-CO2-0.61-0.66
AF347015.8-0.58-0.65
AF347015.31-0.57-0.63
MT-CYB-0.57-0.63
AF347015.21-0.57-0.64
AF347015.33-0.56-0.61
AF347015.27-0.55-0.61
AF347015.2-0.54-0.61
AF347015.15-0.54-0.61
IFI27-0.53-0.61
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI15096576 
GO:0004526ribonuclease P activityTAS9630247 
GO:0016787hydrolase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008033tRNA processingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusTAS9630247 
GO:0005655nucleolar ribonuclease P complexTAS9630247 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
POP1KIAA0061 | MGC17365processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)hPop1 interacts with Rpp40.BIND15096576 
Reconstituted ComplexBioGRID15096576 
POP70610037N12Rik | RPP2 | RPP20processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)Co-purificationBioGRID9630247 
RPP14FLJ31508 | P14ribonuclease P/MRP 14kDa subunitRpp14 interacts with Rpp40.BIND15096576 
-HPRD,BioGRID15096576 
RPP21C6orf135 | FLJ22638ribonuclease P/MRP 21kDa subunitReconstituted ComplexBioGRID15096576 
Rpp21 interacts with Rpp40.BIND15096576 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
GARY_CD5_TARGETS_DN 431263All SZGR genes in this pathway
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN 362238All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_DN 242165All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_DN 281186All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_DN 5940All SZGR genes in this pathway
ELVIDGE_HIF1A_TARGETS_UP 6740All SZGR genes in this pathway
ELVIDGE_HIF1A_AND_HIF2A_TARGETS_UP 4122All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN 770415All SZGR genes in this pathway
SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN 4734All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
MANALO_HYPOXIA_DN 289166All SZGR genes in this pathway
GENTILE_UV_HIGH_DOSE_DN 312203All SZGR genes in this pathway
GENTILE_RESPONSE_CLUSTER_D3 6139All SZGR genes in this pathway
BILD_MYC_ONCOGENIC_SIGNATURE 206117All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_UP 8847All SZGR genes in this pathway
LIN_MELANOMA_COPY_NUMBER_UP 7353All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN 353226All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_UP 212128All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
WONG_EMBRYONIC_STEM_CELL_CORE 335193All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP 211131All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP 281183All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
VANLOO_SP3_TARGETS_DN 8947All SZGR genes in this pathway
KUMAR_PATHOGEN_LOAD_BY_MACROPHAGES 275155All SZGR genes in this pathway


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