Gene Page: HSPH1

Summary
GeneID  10808
Symbol  HSPH1
Synonyms  DKFZp686M05240|HSP105|HSP105A|HSP105B|KIAA0201|NY-CO-25
Description  heat shock 105kDa/110kDa protein 1
See related  HGNC:16969|MIM:610703|Ensembl:ENSG00000120694|HPRD:09990|
Locus tag  RP11-173P16.1
Gene type  protein-coding
Map location  13q12.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
FBXL160.890.92
CYP46A10.870.82
FAM102A0.860.85
SLC25A230.860.89
ANKRD430.850.85
SAPS10.840.88
AC105206.10.840.86
STIM10.840.83
RP5-1187M17.10.830.87
INF20.830.81
Top 10 negatively co-expressed genes
RBMX2-0.51-0.57
DYNLT1-0.49-0.60
C9orf46-0.49-0.56
TUBB2B-0.48-0.50
EXOSC8-0.48-0.49
KIAA1949-0.48-0.39
YBX1-0.47-0.40
IDH1-0.47-0.39
RPS8-0.47-0.52
HEBP2-0.46-0.61
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005524ATP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006986response to unfolded proteinTAS9931472 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmTAS9931472 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ADD1ADDA | MGC3339 | MGC44427adducin 1 (alpha)-HPRD,BioGRID14733918 
CFL1CFLcofilin 1 (non-muscle)Reconstituted Complex
Two-hybrid		BioGRID14733918 
CHD3Mi-2a | Mi2-ALPHA | ZFHchromodomain helicase DNA binding protein 3Two-hybridBioGRID16169070 
DYNLRB1BITH | BLP | DNCL2A | DNLC2A | ROBLD1dynein, light chain, roadblock-type 1Two-hybridBioGRID14733918 
HSPA8HSC54 | HSC70 | HSC71 | HSP71 | HSP73 | HSPA10 | LAP1 | MGC131511 | MGC29929 | NIP71heat shock 70kDa protein 8-HPRD9675148 
PAFAH1B1LIS1 | LIS2 | MDCR | MDS | PAFAHplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa-HPRD14733918 
PAFAH1B3-platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDaReconstituted ComplexBioGRID14733918 
PGK1MGC117307 | MGC142128 | MGC8947 | MIG10 | PGKAphosphoglycerate kinase 1-HPRD,BioGRID14733918 
STK39DCHT | DKFZp686K05124 | PASK | SPAKserine threonine kinase 39 (STE20/SPS1 homolog, yeast)Two-hybridBioGRID14563843 
UBA1A1S9 | A1S9T | A1ST | AMCX1 | GXP1 | MGC4781 | SMAX2 | UBA1A | UBE1 | UBE1Xubiquitin-like modifier activating enzyme 1-HPRD,BioGRID14733918 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
HOLLMANN_APOPTOSIS_VIA_CD40_UP 201125All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
GARY_CD5_TARGETS_DN 431263All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
DOANE_RESPONSE_TO_ANDROGEN_UP 184125All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_UP 430232All SZGR genes in this pathway
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP 13680All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_DN 214133All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
KIM_WT1_TARGETS_8HR_UP 164122All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_UP 162116All SZGR genes in this pathway
ELVIDGE_HYPOXIA_DN 14694All SZGR genes in this pathway
ELVIDGE_HIF1A_TARGETS_UP 6740All SZGR genes in this pathway
ELVIDGE_HIF1A_AND_HIF2A_TARGETS_UP 4122All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
KOINUMA_COLON_CANCER_MSI_DN 85All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP 239157All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN 3123All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_UP 584356All SZGR genes in this pathway
PEREZ_TP63_TARGETS 355243All SZGR genes in this pathway
YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN 8748All SZGR genes in this pathway
CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP 2116All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
CAFFAREL_RESPONSE_TO_THC_DN 3123All SZGR genes in this pathway
CAFFAREL_RESPONSE_TO_THC_8HR_5_DN 118All SZGR genes in this pathway
AMIT_EGF_RESPONSE_60_HELA 4632All SZGR genes in this pathway
MORI_SMALL_PRE_BII_LYMPHOCYTE_DN 7652All SZGR genes in this pathway
ONDER_CDH1_TARGETS_1_DN 169102All SZGR genes in this pathway
UEDA_CENTRAL_CLOCK 8862All SZGR genes in this pathway
LAMB_CCND1_TARGETS 1914All SZGR genes in this pathway
MENSSEN_MYC_TARGETS 5335All SZGR genes in this pathway
UEDA_PERIFERAL_CLOCK 169111All SZGR genes in this pathway
LEE_LIVER_CANCER_MYC_DN 6340All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_DN 12986All SZGR genes in this pathway
GERY_CEBP_TARGETS 12690All SZGR genes in this pathway
ZAMORA_NOS2_TARGETS_UP 6941All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
WANG_SMARCE1_TARGETS_DN 371218All SZGR genes in this pathway
BURTON_ADIPOGENESIS_2 7252All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C0 10772All SZGR genes in this pathway
JACKSON_DNMT1_TARGETS_UP 7757All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN 165106All SZGR genes in this pathway
WENG_POR_TARGETS_GLOBAL_DN 2314All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_DN 14294All SZGR genes in this pathway
BURTON_ADIPOGENESIS_PEAK_AT_8HR 3931All SZGR genes in this pathway
LEE_CALORIE_RESTRICTION_MUSCLE_DN 5128All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN 271175All SZGR genes in this pathway
WENG_POR_TARGETS_LIVER_DN 2011All SZGR genes in this pathway
BILD_SRC_ONCOGENIC_SIGNATURE 6238All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_DN 10567All SZGR genes in this pathway
HELLER_HDAC_TARGETS_DN 292189All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN 281179All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN 159105All SZGR genes in this pathway
WINTER_HYPOXIA_METAGENE 242168All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_UP 374247All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 4936All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_UP 12778All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN 374217All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_C 9260All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
GUO_TARGETS_OF_IRS1_AND_IRS2 9867All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-3206546601Ahsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
miR-369-3p1201271A,m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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