Gene Page: FTCD

Summary
GeneID  10841
Symbol  FTCD
Synonyms  LCHC1
Description  formiminotransferase cyclodeaminase
See related  HGNC:3974|MIM:606806|Ensembl:ENSG00000160282|HPRD:08430|
Locus tag  -
Gene type  protein-coding
Map location  21q22.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PRKACA0.910.90
ENO20.910.92
CLSTN30.910.92
ABCG40.900.88
ATP6AP10.900.93
SV2A0.890.90
AP2A10.890.90
DCTN10.890.90
PLBD20.880.87
ATP1A30.880.88
Top 10 negatively co-expressed genes
AF347015.21-0.54-0.48
GNG11-0.50-0.51
AP002478.3-0.49-0.50
AF347015.31-0.48-0.43
AF347015.2-0.48-0.37
AF347015.8-0.47-0.42
AF347015.18-0.47-0.42
MT-CO2-0.47-0.43
C1orf54-0.46-0.48
NOSTRIN-0.46-0.42
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0030409glutamate formimidoyltransferase activityIEAglutamate (GO term level: 9)-
GO:0005542folic acid bindingIEA-
GO:0016829lyase activityIEA-
GO:0016740transferase activityIEA-
GO:0030412formimidoyltetrahydrofolate cyclodeaminase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006760folic acid and derivative metabolic processTAS10029623 
GO:0006547histidine metabolic processIEA-
GO:0044237cellular metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIEA-
GO:0005737cytoplasmTAS10029623 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GRB14-growth factor receptor-bound protein 14Co-fractionationBioGRID11278563 
TNKS2PARP-5b | PARP-5c | PARP5B | PARP5C | TANK2 | TNKLtankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2Co-fractionationBioGRID11278563 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_HISTIDINE_METABOLISM 2919All SZGR genes in this pathway
KEGG_ONE_CARBON_POOL_BY_FOLATE 1712All SZGR genes in this pathway
REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 200136All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_UP 292168All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_21Q22_AMPLICON 1611All SZGR genes in this pathway
CERVERA_SDHB_TARGETS_1_DN 3822All SZGR genes in this pathway
HEDENFALK_BREAST_CANCER_BRACX_DN 2014All SZGR genes in this pathway
HELLER_HDAC_TARGETS_UP 317208All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN 274165All SZGR genes in this pathway
GRADE_METASTASIS_DN 4531All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP 8550All SZGR genes in this pathway
CERIBELLI_PROMOTERS_INACTIVE_AND_BOUND_BY_NFY 4420All SZGR genes in this pathway
SERVITJA_LIVER_HNF1A_TARGETS_DN 157105All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.