Gene Page: NPFFR2

Summary
GeneID  10886
Symbol  NPFFR2
Synonyms  GPR74|NPFF2|NPGPR
Description  neuropeptide FF receptor 2
See related  HGNC:4525|MIM:607449|Ensembl:ENSG00000056291|HPRD:16244|
Locus tag  -
Gene type  protein-coding
Map location  4q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
INO800.950.95
KDM2A0.940.96
SETD50.940.94
YEATS20.940.96
TGFBRAP10.940.96
CDC2L50.930.95
PRDM150.930.95
PPRC10.930.94
YTHDF10.930.95
NUP2140.930.94
Top 10 negatively co-expressed genes
AF347015.31-0.76-0.85
FXYD1-0.76-0.84
MT-CO2-0.75-0.85
S100B-0.74-0.82
HIGD1B-0.73-0.86
AF347015.33-0.72-0.79
IFI27-0.72-0.81
AC021016.1-0.72-0.82
MT-CYB-0.72-0.80
AF347015.27-0.72-0.80
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008188neuropeptide receptor activityIEANeurotransmitter (GO term level: 8)-
GO:0004872receptor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007186G-protein coupled receptor protein signaling pathwayTAS10079187 
GO:0007165signal transductionIEA-
GO:0009582detection of abiotic stimulusTAS10851242 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS10079187 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
HCRTOX | PPOXhypocretin (orexin) neuropeptide precursor-HPRD12609745 
NPFFFMRFALneuropeptide FF-amide peptide precursor-HPRD10851242 
-HPRD12609745 
NPYPYY4neuropeptide Y-HPRD12609745 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 205136All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 188108All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 184116All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
BASAKI_YBX1_TARGETS_UP 290177All SZGR genes in this pathway
ROVERSI_GLIOMA_LOH_REGIONS 4430All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_DN 12179All SZGR genes in this pathway
HENDRICKS_SMARCA4_TARGETS_DN 5334All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3 718401All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


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