Gene Page: CORO1A

Summary
GeneID  11151
Symbol  CORO1A
Synonyms  CLABP|CLIPINA|FLJ41407|HCORO1|MGC117380|TACO|p57
Description  coronin, actin binding protein, 1A
See related  HGNC:2252|MIM:605000|Ensembl:ENSG00000102879|HPRD:05414|
Locus tag  -
Gene type  protein-coding
Map location  16p11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01775 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ATP5F10.870.87
TCEB10.860.87
SUPT4H10.850.86
COPS60.850.84
UQCRH0.850.85
LSM10.840.82
AC063943.40.840.84
ZDHHC40.840.80
VTI1B0.830.81
MRPL460.830.79
Top 10 negatively co-expressed genes
AF347015.18-0.53-0.40
AF347015.26-0.52-0.42
AF347015.2-0.50-0.42
GATA2-0.49-0.47
FAM38A-0.48-0.47
PPP1R13L-0.47-0.42
AF347015.8-0.47-0.36
AF347015.15-0.46-0.38
TENC1-0.46-0.48
DOCK6-0.46-0.46
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008022protein C-terminus bindingIPI9365277 
GO:0051015actin filament bindingIDA7758584 |15601263 
GO:0042803protein homodimerization activityIDA15601263 
GO:0043548phosphoinositide 3-kinase bindingIDA11094157 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001845phagolysosome formationIMP12132654 
GO:0006928cell motionNAS17341475 
GO:0030036actin cytoskeleton organizationIMP17442961 
GO:0051126negative regulation of actin nucleationIDA17442961 
GO:0031589cell-substrate adhesionIMP17442961 
GO:0050918positive chemotaxisIDA17442961 
GO:0045087innate immune responseNAS17341475 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0001891phagocytic cupIDA17442961 
GO:0005856cytoskeletonIEA-
GO:0005634nucleusIDA17341475 
GO:0005737cytoplasmIDA17341475 
GO:0030027lamellipodiumIDA17442961 
GO:0005886plasma membraneIDA17341475 |17442961 
GO:0031410cytoplasmic vesicleIEA-
GO:0031941filamentous actinIDA15800061 
GO:0030864cortical actin cytoskeletonIDA15800061 
GO:0045335phagocytic vesicleIDA17442961 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DKK1DKK-1 | SKdickkopf homolog 1 (Xenopus laevis)Affinity Capture-MSBioGRID17353931 
THBS1THBS | TSP | TSP1thrombospondin 1-HPRD10749676 
UBE2G2UBC7ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ELVIDGE_HYPOXIA_DN 14694All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_DN 5940All SZGR genes in this pathway
ELVIDGE_HIF1A_TARGETS_UP 6740All SZGR genes in this pathway
ELVIDGE_HIF1A_AND_HIF2A_TARGETS_UP 4122All SZGR genes in this pathway
BIDUS_METASTASIS_DN 16193All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_UP 197135All SZGR genes in this pathway
MCBRYAN_TERMINAL_END_BUD_DN 76All SZGR genes in this pathway
MATTIOLI_MGUS_VS_PCL 11662All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN 164111All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP 380213All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN 165104All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
PENG_GLUCOSE_DEPRIVATION_UP 4826All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP 8758All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_DN 309206All SZGR genes in this pathway
SASAKI_ADULT_T_CELL_LEUKEMIA 176122All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP 6647All SZGR genes in this pathway
MATSUDA_NATURAL_KILLER_DIFFERENTIATION 475313All SZGR genes in this pathway
ASTIER_INTEGRIN_SIGNALING 5944All SZGR genes in this pathway
LENAOUR_DENDRITIC_CELL_MATURATION_DN 12890All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN 225163All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
RAMALHO_STEMNESS_DN 7455All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_DN 245144All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_UP 487303All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP 2216All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_UP 253147All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G 9562All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G 17196All SZGR genes in this pathway
WALLACE_PROSTATE_CANCER_RACE_UP 299167All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN 353226All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP 11170All SZGR genes in this pathway
PARK_APL_PATHOGENESIS_DN 5035All SZGR genes in this pathway
LEE_DIFFERENTIATING_T_LYMPHOCYTE 200115All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MEISSNER_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 148All SZGR genes in this pathway
MEISSNER_BRAIN_ICP_WITH_H3K4ME3 3217All SZGR genes in this pathway
VALK_AML_CLUSTER_6 3322All SZGR genes in this pathway
MIKKELSEN_MCV6_ICP_WITH_H3K27ME3 7446All SZGR genes in this pathway
MIKKELSEN_MEF_ICP_WITH_H3K4ME3_AND_H3K27ME3 3834All SZGR genes in this pathway
MARSON_FOXP3_TARGETS_UP 6643All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 13785All SZGR genes in this pathway
MIKKELSEN_NPC_ICP_WITH_H3K4ME3 445257All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_DN 213127All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
DELPUECH_FOXO3_TARGETS_UP 6849All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
PEDRIOLI_MIR31_TARGETS_UP 221120All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_DN 211119All SZGR genes in this pathway


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