Gene Page: LDB3

Summary
GeneID  11155
Symbol  LDB3
Synonyms  CYPHER|FLJ35865|KIAA01613|KIAA0613|ORACLE|PDLIM6|ZASP|ldb3z1|ldb3z4
Description  LIM domain binding 3
See related  HGNC:15710|MIM:605906|Ensembl:ENSG00000122367|HPRD:16172|
Locus tag  -
Gene type  protein-coding
Map location  10q22.3-q23.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PMPCB0.890.85
MRPS350.880.85
OLA10.880.83
TTRAP0.870.84
CUL20.870.83
VPS450.870.84
UBE2D30.870.84
EIF2S10.860.86
STRAP0.860.82
POLR3F0.860.84
Top 10 negatively co-expressed genes
MT-CO2-0.74-0.67
AF347015.2-0.74-0.68
AF347015.8-0.73-0.67
AF347015.31-0.73-0.67
MT-CYB-0.72-0.66
AF347015.21-0.71-0.61
AF347015.26-0.70-0.65
AF347015.15-0.70-0.66
AF347015.33-0.69-0.64
AF347015.18-0.69-0.67
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI10427098 
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0042995cell projectionIEAaxon (GO term level: 4)-
GO:0005856cytoskeletonIDA10427098 
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTN2CMD1AAactinin, alpha 2-HPRD,BioGRID10391924 
ZASP interacts with Alpha-actinin 2.BIND11842093 
MYOZ1CS-2 | FATZ | MYOZmyozenin 1ZASP/Cypher-2 interacts with Calsarcin-2.BIND11842093 
ZASP/Cypher-1 interacts with Calsarcin-2. This interaction was modeled on a demonstrated interaction between mouse ZASP/Cypher-1 and human Calsarcin-2.BIND11842093 
MYOZ2C4orf5 | CS-1myozenin 2ZASP/Cypher-2 interacts with Calsarcin-1.BIND11842093 
ZASP/Cypher-1 interacts with Calsarcin-1. This interaction was modeled on a demonstrated interaction between mouse ZASP/Cypher-1 and human Calsarcin-1.BIND11842093 
MYOZ3CS-3 | CS3 | FRP3myozenin 3ZASP/Cypher-1 interacts with Calsarcin-3. This interaction was modeled on a demonstrated interaction between mouse ZASP/Cypher-1 and human Calsarcin-3.BIND11842093 
ZASP/Cypher-2 interacts with Calsarcin-3.BIND11842093 
-HPRD11842093 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
HOLLMANN_APOPTOSIS_VIA_CD40_DN 267178All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_DN 244147All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_DN 367220All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP 185119All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN 800473All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP 207128All SZGR genes in this pathway
EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION 5026All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_DN 193112All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP 380213All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_DN 160110All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
AFFAR_YY1_TARGETS_UP 214133All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
KUNINGER_IGF1_VS_PDGFB_TARGETS_UP 8251All SZGR genes in this pathway
CHENG_IMPRINTED_BY_ESTRADIOL 11068All SZGR genes in this pathway
DAIRKEE_CANCER_PRONE_RESPONSE_E2 2821All SZGR genes in this pathway
MIKKELSEN_MEF_LCP_WITH_H3K4ME3 12868All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway


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