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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Gene Page: KLF12

Summary

GeneID

11278

Symbol

KLF12

Synonyms

AP-2rep|AP2REP|HSPC122

Description

Kruppel-like factor 12

Locus tag

Gene type

protein-coding

Map location

13q22

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003700

transcription factor activity

IDA

16615998

GO:0003714

transcription corepressor activity

TAS

10704285

GO:0008270

zinc ion binding

IEA

GO:0046872

metal ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

IDA

16615998

GO:0006350

transcription

IEA

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

GO:0005634

nucleus

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CTBP1	BARS \| MGC104684	C-terminal binding protein 1	-	HPRD	11373277
EHMT2	BAT8 \| C6orf30 \| DKFZp686H08213 \| FLJ35547 \| G9A \| KMT1C \| NG36 \| NG36/G9a	euchromatic histone-lysine N-methyltransferase 2	Two-hybrid	BioGRID	16189514

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
PARENT_MTOR_SIGNALING_UP	567	375	All SZGR genes in this pathway
ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP	183	119	All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN	384	220	All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_DN	244	147	All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP	544	308	All SZGR genes in this pathway
ODONNELL_METASTASIS_UP	82	58	All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP	170	114	All SZGR genes in this pathway
KAN_RESPONSE_TO_ARSENIC_TRIOXIDE	123	80	All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_UP	134	93	All SZGR genes in this pathway
AMUNDSON_RESPONSE_TO_ARSENITE	217	143	All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK	1442	892	All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	811	508	All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN	428	306	All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR	681	420	All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP	578	341	All SZGR genes in this pathway
MELLMAN_TUT1_TARGETS_DN	47	29	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A	898	516	All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN	448	282	All SZGR genes in this pathway
PECE_MAMMARY_STEM_CELL_DN	146	88	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-101	9108	9114	1A	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-124.1	4018	4024	1A	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-137	1565	1572	1A,m8	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
				hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
				hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-138	8339	8345	1A	hsa-miR-138^brain	AGCUGGUGUUGUGAAUC
				hsa-miR-138^brain	AGCUGGUGUUGUGAAUC
				hsa-miR-138^brain	AGCUGGUGUUGUGAAUC
miR-141/200a	9220	9226	1A	hsa-miR-141	UAACACUGUCUGGUAAAGAUGG
miR-141/200a	9220	9226	1A	hsa-miR-200a	UAACACUGUCUGGUAACGAUGU
miR-144	9108	9114	1A	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-151	8463	8470	1A,m8	hsa-miR-151^brain	ACUAGACUGAAGCUCCUUGAGG
miR-17-5p/20/93.mr/106/519.d	3468	3474	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
				hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-188	1077	1083	m8	hsa-miR-188	CAUCCCUUGCAUGGUGGAGGGU
miR-194	469	475	m8	hsa-miR-194	UGUAACAGCAACUCCAUGUGGA
miR-199	901	907	m8	hsa-miR-199a	CCCAGUGUUCAGACUACCUGUUC
miR-199	901	907	m8	hsa-miR-199b	CCCAGUGUUUAGACUAUCUGUUC
miR-200bc/429	3740	3746	m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
				hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-203.1	2886	2892	1A	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-204/211	1076	1082	m8	hsa-miR-204^brain	UUCCCUUUGUCAUCCUAUGCCU
miR-204/211	1076	1082	m8	hsa-miR-211	UUCCCUUUGUCAUCCUUCGCCU
miR-205	9358	9364	m8	hsa-miR-205	UCCUUCAUUCCACCGGAGUCUG
miR-205	9358	9364	m8	hsa-miR-205	UCCUUCAUUCCACCGGAGUCUG
miR-217	3737	3744	1A,m8	hsa-miR-217	UACUGCAUCAGGAACUGAUUGGAU
miR-218	2922	2928	m8	hsa-miR-218^brain	UUGUGCUUGAUCUAACCAUGU
miR-218	2922	2928	m8	hsa-miR-218^brain	UUGUGCUUGAUCUAACCAUGU
miR-224	8441	8447	1A	hsa-miR-224	CAAGUCACUAGUGGUUCCGUUUA
miR-25/32/92/363/367	1745	1751	1A	hsa-miR-25^brain	CAUUGCACUUGUCUCGGUCUGA
				hsa-miR-32	UAUUGCACAUUACUAAGUUGC
				hsa-miR-92	UAUUGCACUUGUCCCGGCCUG
				hsa-miR-367	AAUUGCACUUUAGCAAUGGUGA
				hsa-miR-92b^SZ	UAUUGCACUCGUCCCGGCCUC
				hsa-miR-25^brain	CAUUGCACUUGUCUCGGUCUGA
				hsa-miR-32	UAUUGCACAUUACUAAGUUGC
				hsa-miR-92	UAUUGCACUUGUCCCGGCCUG
				hsa-miR-367	AAUUGCACUUUAGCAAUGGUGA
				hsa-miR-92b^SZ	UAUUGCACUCGUCCCGGCCUC
miR-27	9301	9307	1A	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	9301	9307	1A	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC
miR-29	1339	1346	1A,m8	hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU
miR-329	8481	8487	m8	hsa-miR-329^brain	AACACACCUGGUUAACCUCUUU
miR-33	8294	8300	1A	hsa-miR-33	GUGCAUUGUAGUUGCAUUG
miR-33	8294	8300	1A	hsa-miR-33b	GUGCAUUGCUGUUGCAUUGCA
miR-34/449	4249	4255	m8	hsa-miR-34a^brain	UGGCAGUGUCUUAGCUGGUUGUU
				hsa-miR-34c	AGGCAGUGUAGUUAGCUGAUUGC
				hsa-miR-449	UGGCAGUGUAUUGUUAGCUGGU
				hsa-miR-449b	AGGCAGUGUAUUGUUAGCUGGC
miR-342	8227	8233	1A	hsa-miR-342^brain	UCUCACACAGAAAUCGCACCCGUC
miR-34b	4250	4256	m8	hsa-miR-34b	UAGGCAGUGUCAUUAGCUGAUUG
miR-370	57	63	m8	hsa-miR-370^brain	GCCUGCUGGGGUGGAACCUGG
miR-370	57	63	m8	hsa-miR-370^brain	GCCUGCUGGGGUGGAACCUGG
miR-376	9289	9295	1A	hsa-miR-376a	AUCAUAGAGGAAAAUCCACGU
miR-376	9289	9295	1A	hsa-miR-376b	AUCAUAGAGGAAAAUCCAUGUU
miR-376c	8180	8186	m8	hsa-miR-376c	AACAUAGAGGAAAUUCCACG
miR-381	9053	9059	m8	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-381	9053	9059	m8	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-409-5p	163	169	m8	hsa-miR-409-5p	AGGUUACCCGAGCAACUUUGCA
miR-410	8989	8995	1A	hsa-miR-410	AAUAUAACACAGAUGGCCUGU
miR-539	7353	7360	1A,m8	hsa-miR-539	GGAGAAAUUAUCCUUGGUGUGU
miR-542-3p	825	831	m8	hsa-miR-542-3p	UGUGACAGAUUGAUAACUGAAA
miR-7	4218	4225	1A,m8	hsa-miR-7^SZ	UGGAAGACUAGUGAUUUUGUUG
miR-9	3776	3782	m8	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA
miR-93.hd/291-3p/294/295/302/372/373/520	3467	3473	m8	hsa-miR-93^brain	AAAGUGCUGUUCGUGCAGGUAG
				hsa-miR-302a	UAAGUGCUUCCAUGUUUUGGUGA
				hsa-miR-302b	UAAGUGCUUCCAUGUUUUAGUAG
				hsa-miR-302c	UAAGUGCUUCCAUGUUUCAGUGG
				hsa-miR-302d	UAAGUGCUUCCAUGUUUGAGUGU
				hsa-miR-372	AAAGUGCUGCGACAUUUGAGCGU
				hsa-miR-373	GAAGUGCUUCGAUUUUGGGGUGU
				hsa-miR-520e	AAAGUGCUUCCUUUUUGAGGG
				hsa-miR-520a	AAAGUGCUUCCCUUUGGACUGU
				hsa-miR-520b	AAAGUGCUUCCUUUUAGAGGG
				hsa-miR-520c	AAAGUGCUUCCUUUUAGAGGGUU
				hsa-miR-520d	AAAGUGCUUCUCUUUGGUGGGUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.