Gene Page: CNTN1

Summary
GeneID  1272
Symbol  CNTN1
Synonyms  F3|GP135
Description  contactin 1
See related  HGNC:2171|MIM:600016|Ensembl:ENSG00000018236|HPRD:07189|
Locus tag  -
Gene type  protein-coding
Map location  12q11-q12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0389 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
COL1A10.920.81
COL1A20.910.82
LUM0.900.64
COL6A30.880.57
OLFML30.860.65
BMP50.860.57
ITIH20.850.43
SLC6A40.850.47
PCOLCE0.850.69
OGN0.830.44
Top 10 negatively co-expressed genes
LHPP-0.29-0.37
HLA-F-0.28-0.40
RGN-0.28-0.43
SEPT4-0.28-0.58
AC018755.7-0.28-0.44
FBXO2-0.28-0.38
AF347015.33-0.28-0.46
ALDOC-0.28-0.39
HEPN1-0.28-0.40
S100A1-0.27-0.51
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionNAS7959734 
GO:0007219Notch signaling pathwayIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionTAS7959734 
GO:0005886plasma membraneIEA-
GO:0031225anchored to membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ANK3ANKYRIN-G | FLJ45464ankyrin 3, node of Ranvier (ankyrin G)Affinity Capture-WesternBioGRID14761957 
CNTN2AXT | DKFZp781D102 | FLJ42746 | MGC157722 | TAG-1 | TAX | TAX1contactin 2 (axonal)-HPRD,BioGRID12139915 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YES-HPRD,BioGRID7595520 
L1CAMCAML1 | CD171 | HSAS | HSAS1 | MASA | MIC5 | N-CAML1 | S10 | SPG1L1 cell adhesion molecule-HPRD,BioGRID7595520 
NOTCH1TAN1 | hN1Notch homolog 1, translocation-associated (Drosophila)-HPRD,BioGRID14567914 
NOTCH2AGS2 | hN2Notch homolog 2 (Drosophila)-HPRD,BioGRID14567914 
PRNPASCR | CD230 | CJD | GSS | MGC26679 | PRIP | PrP | PrP27-30 | PrP33-35C | PrPc | prionprion protein-HPRD15146195 
PTPRBDKFZp686E2262 | DKFZp686H15164 | FLJ44133 | HPTP-BETA | HPTPB | MGC142023 | MGC59935 | PTPB | R-PTP-BETA | VEPTPprotein tyrosine phosphatase, receptor type, B-HPRD,BioGRID7628014 |9049255 
|9584610 |12700241 
PTPRZ1HPTPZ | HPTPzeta | PTP-ZETA | PTP18 | PTPRZ | PTPZ | RPTPB | RPTPbeta | phosphacanprotein tyrosine phosphatase, receptor-type, Z polypeptide 1Affinity Capture-WesternBioGRID12700241 
SCN1BGEFSP1sodium channel, voltage-gated, type I, betaAffinity Capture-WesternBioGRID14761957 
SCNN1BENaCb | ENaCbeta | SCNEBsodium channel, nonvoltage-gated 1, beta-HPRD11567041 |14761957 
TNCHXB | MGC167029 | TNtenascin C-HPRD10103110 
TNRMGC149328 | TN-Rtenascin R (restrictin, janusin)-HPRD9081628 |9335257 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_ADHESION_MOLECULES_CAMS 13493All SZGR genes in this pathway
PID_NOTCH_PATHWAY 5949All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS 2718All SZGR genes in this pathway
REACTOME_SIGNALING_BY_NOTCH1 7046All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_L1CAM_INTERACTIONS 8662All SZGR genes in this pathway
REACTOME_SIGNALING_BY_NOTCH 10364All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_DN 4629All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_DN 367220All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
CHEBOTAEV_GR_TARGETS_DN 12073All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_UP 271175All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_UP 201127All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_C 11347All SZGR genes in this pathway
JI_METASTASIS_REPRESSED_BY_STK11 2717All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
NGUYEN_NOTCH1_TARGETS_UP 2923All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM 302191All SZGR genes in this pathway
MCCABE_BOUND_BY_HOXC6 469239All SZGR genes in this pathway
MCCABE_HOXC6_TARGETS_DN 2115All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_PR_DN 4434All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.1233239m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/5062332391Ahsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-299-5p2402461Ahsa-miR-299-5pUGGUUUACCGUCCCACAUACAU
miR-4211561621Ahsa-miR-421GGCCUCAUUAAAUGUUUGUUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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