Gene Page

Home
Datasets
Search
Analysis & Tools
Documents
About SZGR
Quick search: (e.g. 207 or AKT)

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

Release Site Map Support Contact us

Gene Page: CSNK2A2

Summary

GeneID

1459

Symbol

CSNK2A2

Synonyms

CK2A2|CSNK2A1|FLJ43934

Description

casein kinase 2, alpha prime polypeptide

Locus tag

Gene type

protein-coding

Map location

16q21

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.2826

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0005524

ATP binding

IEA

GO:0004674

protein serine/threonine kinase activity

IEA

GO:0016740

transferase activity

IEA

GO:0047485

protein N-terminus binding

IPI

11972058

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006468

protein amino acid phosphorylation

IEA

GO:0016055

Wnt receptor signaling pathway

IEA

GO:0051726

regulation of cell cycle

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ARR3	ARRX	arrestin 3, retinal (X-arrestin)	Biochemical Activity	BioGRID	11877451
ATF1	EWS-ATF1 \| FUS/ATF-1 \| TREB36	activating transcription factor 1	-	HPRD,BioGRID	9685505
ATF2	CRE-BP1 \| CREB2 \| HB16 \| MGC111558 \| TREB7	activating transcription factor 2	-	HPRD,BioGRID	9685505
BRF1	BRF \| FLJ42674 \| FLJ43034 \| GTF3B \| MGC105048 \| TAF3B2 \| TAF3C \| TAFIII90 \| TF3B90 \| TFIIIB90 \| hBRF	BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)	Affinity Capture-Western	BioGRID	11997511
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	-	HPRD,BioGRID	9685505
CSN3	CSN10 \| CSNK \| KCA	casein kappa	-	HPRD	11827172
CSNK2B	CK2B \| CK2N \| CSK2B \| G5A \| MGC138222 \| MGC138224	casein kinase 2, beta polypeptide	-	HPRD,BioGRID	9571630
CSNK2B	CK2B \| CK2N \| CSK2B \| G5A \| MGC138222 \| MGC138224	casein kinase 2, beta polypeptide	CK2-alpha' subunit interacts with CK2-beta subunit.	BIND	7768894
FGF1	AFGF \| ECGF \| ECGF-beta \| ECGFA \| ECGFB \| FGF-alpha \| FGFA \| GLIO703 \| HBGF1	fibroblast growth factor 1 (acidic)	-	HPRD,BioGRID	12145206
FGF2	BFGF \| FGFB \| HBGF-2	fibroblast growth factor 2 (basic)	Reconstituted Complex	BioGRID	12145206
FGF2	BFGF \| FGFB \| HBGF-2	fibroblast growth factor 2 (basic)	-	HPRD	7735329
FOS	AP-1 \| C-FOS	v-fos FBJ murine osteosarcoma viral oncogene homolog	-	HPRD,BioGRID	9685505
GDNF	ATF1 \| ATF2 \| HFB1-GDNF	glial cell derived neurotrophic factor	-	HPRD	9685505
HSP90AA1	FLJ31884 \| HSP86 \| HSP89A \| HSP90A \| HSP90N \| HSPC1 \| HSPCA \| HSPCAL1 \| HSPCAL4 \| HSPN \| Hsp89 \| Hsp90 \| LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	-	HPRD,BioGRID	7794926
HSP90B1	ECGP \| GP96 \| GRP94 \| TRA1	heat shock protein 90kDa beta (Grp94), member 1	-	HPRD,BioGRID	11557039
JUN	AP-1 \| AP1 \| c-Jun	jun oncogene	Far Western Reconstituted Complex	BioGRID	9685505
KLF1	EKLF	Kruppel-like factor 1 (erythroid)	-	HPRD,BioGRID	9722526
MAPK14	CSBP1 \| CSBP2 \| CSPB1 \| EXIP \| Mxi2 \| PRKM14 \| PRKM15 \| RK \| SAPK2A \| p38 \| p38ALPHA	mitogen-activated protein kinase 14	-	HPRD	10747897
MGMT	-	O-6-methylguanine-DNA methyltransferase	Biochemical Activity	BioGRID	10667577
NAP1L4	MGC4565 \| NAP2 \| NAP2L \| hNAP2	nucleosome assembly protein 1-like 4	-	HPRD	10764593
NCL	C23 \| FLJ45706	nucleolin	Affinity Capture-Western Biochemical Activity Far Western	BioGRID	8663258
PAK1	MGC130000 \| MGC130001 \| PAKalpha	p21 protein (Cdc42/Rac)-activated kinase 1	-	HPRD	10938077
PIN1	DOD \| UBL5	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	-	HPRD,BioGRID	11940573
PRNP	ASCR \| CD230 \| CJD \| GSS \| MGC26679 \| PRIP \| PrP \| PrP27-30 \| PrP33-35C \| PrPc \| prion	prion protein	PrPc interacts with CSNK2A2 (CK2 alpha prime). This interaction was modeled on a demonstrated interaction between bovine PrPc and human CSNK2A2 (CK2 alpha prime).	BIND	11062072
PTEN	10q23del \| BZS \| MGC11227 \| MHAM \| MMAC1 \| PTEN1 \| TEP1	phosphatase and tensin homolog	Biochemical Activity Reconstituted Complex	BioGRID	12297295
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Affinity Capture-Western Biochemical Activity	BioGRID	10938077
RNPS1	E5.1 \| MGC117332	RNA binding protein S1, serine-rich domain	Affinity Capture-MS	BioGRID	17353931
TOP1	TOPI	topoisomerase (DNA) I	Biochemical Activity	BioGRID	2998765

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_WNT_SIGNALING_PATHWAY	151	112	All SZGR genes in this pathway
KEGG_ADHERENS_JUNCTION	75	53	All SZGR genes in this pathway
KEGG_TIGHT_JUNCTION	134	86	All SZGR genes in this pathway
PID_NFKAPPAB_ATYPICAL_PATHWAY	17	15	All SZGR genes in this pathway
PID_DNA_PK_PATHWAY	16	10	All SZGR genes in this pathway
PID_ECADHERIN_NASCENT_AJ_PATHWAY	39	33	All SZGR genes in this pathway
PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY	38	29	All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY	396	292	All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE	251	188	All SZGR genes in this pathway
REACTOME_L1CAM_INTERACTIONS	86	62	All SZGR genes in this pathway
REACTOME_SIGNAL_TRANSDUCTION_BY_L1	34	25	All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN	526	357	All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN	455	304	All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_DN	162	116	All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_DN	536	332	All SZGR genes in this pathway
PROVENZANI_METASTASIS_UP	194	112	All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN	508	354	All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP	536	340	All SZGR genes in this pathway
ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_UP	63	44	All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK	1652	1023	All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	811	508	All SZGR genes in this pathway
DEN_INTERACT_WITH_LCA5	26	21	All SZGR genes in this pathway
MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_UP	42	24	All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C8	72	56	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP	390	242	All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP	244	165	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP	1691	1088	All SZGR genes in this pathway
MATZUK_SPERMATOZOA	114	77	All SZGR genes in this pathway
BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_DN	127	75	All SZGR genes in this pathway
FIRESTEIN_PROLIFERATION	175	125	All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S2	115	74	All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP	397	206	All SZGR genes in this pathway
LU_EZH2_TARGETS_DN	414	237	All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN	1972	1213	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-181	191	197	1A	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-208	70	77	1A,m8	hsa-miR-208	AUAAGACGAGCAAAAAGCUUGU
miR-23	256	263	1A,m8	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
miR-23	256	263	1A,m8	hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-323	256	262	1A	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU
miR-346	105	111	1A	hsa-miR-346^brain	UGUCUGCCCGCAUGCCUGCCUCU
miR-433-5p	167	173	1A	hsa-miR-433-5p	UACGGUGAGCCUGUCAUUAUUC
miR-496	193	199	1A	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-499	71	77	1A	hsa-miR-499	UUAAGACUUGCAGUGAUGUUUAA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.