Gene Page: CYP2C9

Summary
GeneID  1559
Symbol  CYP2C9
Synonyms  CPC9|CYP2C|CYP2C10|MGC149605|MGC88320|P450IIC9
Description  cytochrome P450, family 2, subfamily C, polypeptide 9
See related  HGNC:2623|MIM:601130|Ensembl:ENSG00000138109|HPRD:03084|
Locus tag  -
Gene type  protein-coding
Map location  10q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenic]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ARPP-210.800.85
TMEM1450.770.77
SLC26A80.760.76
PARP20.740.73
SNX320.720.71
OR2W30.720.81
R3HDM10.720.79
ZFR20.710.78
CCDC640.710.74
C3orf620.710.69
Top 10 negatively co-expressed genes
MT-CO2-0.58-0.54
AF347015.31-0.57-0.53
AF347015.8-0.57-0.53
AF347015.33-0.56-0.50
AF347015.26-0.56-0.53
AF347015.2-0.56-0.52
MT-CYB-0.55-0.51
AF347015.27-0.55-0.51
AF347015.15-0.55-0.51
AF347015.21-0.53-0.52
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005506iron ion bindingIEA-
GO:0020037heme bindingIEA-
GO:0016712oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygenIEA-
GO:0009055electron carrier activityIEA-
GO:0018675(S)-limonene 6-monooxygenase activityIEA-
GO:0018676(S)-limonene 7-monooxygenase activityIEA-
GO:00337674-hydroxyacetophenone monooxygenase activityIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0055114oxidation reductionNAS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005792microsomeTAS2827463 |3032244 
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005783endoplasmic reticulumNAS-
GO:0016020membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
PORCPR | CYPOR | DKFZp686G04235 | FLJ26468 | P450RP450 (cytochrome) oxidoreductase-HPRD,BioGRID9398194 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ARACHIDONIC_ACID_METABOLISM 5836All SZGR genes in this pathway
KEGG_LINOLEIC_ACID_METABOLISM 2916All SZGR genes in this pathway
KEGG_RETINOL_METABOLISM 6437All SZGR genes in this pathway
KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450 7044All SZGR genes in this pathway
KEGG_DRUG_METABOLISM_CYTOCHROME_P450 7247All SZGR genes in this pathway
REACTOME_BIOLOGICAL_OXIDATIONS 13991All SZGR genes in this pathway
REACTOME_XENOBIOTICS 1611All SZGR genes in this pathway
REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE 5134All SZGR genes in this pathway
REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS 7050All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP 485293All SZGR genes in this pathway
WANG_CLIM2_TARGETS_UP 269146All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_DN 367220All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP 544308All SZGR genes in this pathway
XU_HGF_TARGETS_REPRESSED_BY_AKT1_DN 9558All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_DN 357212All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
HSIAO_LIVER_SPECIFIC_GENES 244154All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN 274165All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN 17997All SZGR genes in this pathway
WOO_LIVER_CANCER_RECURRENCE_DN 8054All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S3 266180All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_DN 210141All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway


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