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| GeneID |
1621
|
| Symbol |
DBH
|
| Synonyms |
DBM
|
| Description |
dopamine beta-hydroxylase (dopamine beta-monooxygenase) |
| See related |
HGNC:2689|MIM:609312|Ensembl:ENSG00000123454|HPRD:01963| |
| Locus tag |
RP11-317B10.1 |
| Gene type |
protein-coding |
| Map location |
9q34 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia] | Click to show detail | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 2 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| PPP1CB | 0.92 | 0.91 | | |
| FAM49B | 0.91 | 0.90 | | |
| STX12 | 0.90 | 0.91 | | |
| RAB2A | 0.90 | 0.91 | | |
| CNOT7 | 0.90 | 0.89 | | |
| UBE2N | 0.90 | 0.88 | | |
| AZIN1 | 0.90 | 0.88 | | |
| TMEM68 | 0.90 | 0.89 | | |
| RAB18 | 0.90 | 0.90 | | |
| TTC33 | 0.89 | 0.91 | | |
Top 10 negatively co-expressed genes | | MT-CO2 | -0.65 | -0.64 | | |
| AF347015.8 | -0.65 | -0.66 | | |
| AF347015.26 | -0.65 | -0.65 | | |
| AF347015.2 | -0.65 | -0.64 | | |
| MT-CYB | -0.64 | -0.64 | | |
| AF347015.33 | -0.64 | -0.63 | | |
| AF347015.15 | -0.63 | -0.64 | | |
| AF347015.31 | -0.61 | -0.61 | | |
| GPT | -0.60 | -0.63 | | |
| AF347015.27 | -0.60 | -0.61 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004500 | dopamine beta-monooxygenase activity | IEA | dopamine (GO term level: 6) | - |
| GO:0005507 | copper ion binding | IEA | | - |
| GO:0004497 | monooxygenase activity | IEA | | - |
| GO:0031418 | L-ascorbic acid binding | IEA | | - |
| GO:0046872 | metal ion binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007268 | synaptic transmission | TAS | neuron, Synap, Neurotransmitter (GO term level: 6) | 2880016 |
| GO:0009987 | cellular process | IEA | | - |
| GO:0006548 | histidine catabolic process | IEA | | - |
| GO:0042423 | catecholamine biosynthetic process | IEA | | - |
| GO:0055114 | oxidation reduction | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005576 | extracellular region | NAS | | 14718574 |
| GO:0005624 | membrane fraction | TAS | | 3443096 |
| GO:0005625 | soluble fraction | TAS | | 3443096 |
| GO:0005737 | cytoplasm | TAS | | 3443096 |
| GO:0016020 | membrane | IEA | | - |
| GO:0016021 | integral to membrane | IEA | | - |
| GO:0042583 | chromaffin granule | NAS | | - |
| GO:0031410 | cytoplasmic vesicle | IEA | | - |
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