Gene Page: DCN

Summary
GeneID  1634
Symbol  DCN
Synonyms  CSCD|DSPG2|PG40|PGII|PGS2|SLRR1B
Description  decorin
See related  HGNC:2705|MIM:125255|Ensembl:ENSG00000011465|HPRD:00501|
Locus tag  -
Gene type  protein-coding
Map location  12q21.33
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0119 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
AKR1C10.920.95
STMN20.830.91
ACAT20.820.90
TUBA1A0.820.91
TUBB30.820.91
COTL10.820.84
CDC420.810.90
TSPAN20.810.87
SMAP10.800.87
PPP3CC0.800.89
Top 10 negatively co-expressed genes
HLA-F-0.66-0.75
HEPN1-0.62-0.73
SPARCL1-0.62-0.67
AF347015.27-0.62-0.81
AF347015.33-0.62-0.81
SLC16A11-0.61-0.64
AF347015.31-0.61-0.77
MT-CO2-0.60-0.78
AF347015.8-0.59-0.80
TSC22D4-0.59-0.72
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009887organ morphogenesisTAS7961765 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005578proteinaceous extracellular matrixIEA-
GO:0005634nucleusIDA18029348 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AHSGA2HS | AHS | FETUA | HSGAalpha-2-HS-glycoprotein-HPRD,BioGRID12071714 
C1QA-complement component 1, q subcomponent, A chain-HPRD,BioGRID1431141 
COL14A1UNDcollagen, type XIV, alpha 1-HPRD,BioGRID9252349 
COL1A1OI4collagen, type I, alpha 1-HPRD1468447 |9675033 
COL1A2OI4collagen, type I, alpha 2-HPRD,BioGRID1468447 |2375748 
|9675033 
COL2A1ANFH | AOM | COL11A3 | MGC131516 | SEDCcollagen, type II, alpha 1-HPRD10382266 
COL4A1arrestencollagen, type IV, alpha 1-HPRD10382266 
COL4A2DKFZp686I14213 | FLJ22259collagen, type IV, alpha 2-HPRD10382266 
COL4A3-collagen, type IV, alpha 3 (Goodpasture antigen)-HPRD10382266 
COL4A4CA44collagen, type IV, alpha 4-HPRD10382266 
COL4A5ASLN | ATS | CA54 | MGC167109 | MGC42377collagen, type IV, alpha 5-HPRD10382266 
COL4A6MGC88184collagen, type IV, alpha 6-HPRD10382266 
COL6A1OPLLcollagen, type VI, alpha 1Reconstituted ComplexBioGRID1544908 
EGFRERBB | ERBB1 | HER1 | PIG61 | mENAepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)-HPRD,BioGRID9988678 |12105206 
ELNFLJ38671 | FLJ43523 | SVAS | WBS | WSelastin-HPRD,BioGRID11723132 
FBN1FBN | MASS | MFS1 | OCTD | SGS | WMSfibrillin 1-HPRD10793130 
FLNAABP-280 | ABPX | DKFZp434P031 | FLN | FLN1 | FMD | MNS | NHBP | OPD | OPD1 | OPD2filamin A, alpha (actin binding protein 280)-HPRD,BioGRID12106908 
FN1CIG | DKFZp686F10164 | DKFZp686H0342 | DKFZp686I1370 | DKFZp686O13149 | ED-B | FINC | FN | FNZ | GFND | GFND2 | LETS | MSFfibronectin 1-HPRD1468447 
PLA2G2AMOM1 | PLA2 | PLA2B | PLA2L | PLA2S | PLAS1 | sPLA2phospholipase A2, group IIA (platelets, synovial fluid)-HPRD,BioGRID10747008 
SFTPA1BAC068139.6 | MGC133365 | PSAP | PSPA | SFTP1 | SFTPA1surfactant protein A1BReconstituted ComplexBioGRID12730206 
SFTPDCOLEC7 | PSP-D | SFTP4 | SP-Dsurfactant protein D-HPRD,BioGRID12730206 
TGFB1CED | DPD1 | TGFB | TGFbetatransforming growth factor, beta 1-HPRD7638106 |7798269 
Reconstituted ComplexBioGRID7798269 |8093006 
|9675033 
TGFB2MGC116892 | TGF-beta2transforming growth factor, beta 2Reconstituted ComplexBioGRID9675033 
THBS1THBS | TSP | TSP1thrombospondin 1-HPRD1550960 |9328841 
TNFDIF | TNF-alpha | TNFA | TNFSF2tumor necrosis factor (TNF superfamily, member 2)-HPRD,BioGRID12387878 
WISP1CCN4 | WISP1c | WISP1i | WISP1tcWNT1 inducible signaling pathway protein 1-HPRD11598131 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_TGF_BETA_SIGNALING_PATHWAY 8664All SZGR genes in this pathway
PID_FRA_PATHWAY 3728All SZGR genes in this pathway
REACTOME_CS_DS_DEGRADATION 129All SZGR genes in this pathway
REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS 2115All SZGR genes in this pathway
REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM 4933All SZGR genes in this pathway
REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM 5233All SZGR genes in this pathway
REACTOME_GLYCOSAMINOGLYCAN_METABOLISM 11169All SZGR genes in this pathway
REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS 2517All SZGR genes in this pathway
REACTOME_METABOLISM_OF_CARBOHYDRATES 247154All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_MARKERS_DN 2014All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_DN 76All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP 14699All SZGR genes in this pathway
WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN 199124All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP 12895All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP 11784All SZGR genes in this pathway
DELYS_THYROID_CANCER_DN 232154All SZGR genes in this pathway
NADERI_BREAST_CANCER_PROGNOSIS_DN 1813All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_DN 11878All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_UP 1913All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN 394258All SZGR genes in this pathway
WONG_ENDMETRIUM_CANCER_DN 8253All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP 207128All SZGR genes in this pathway
KORKOLA_TERATOMA 3925All SZGR genes in this pathway
KORKOLA_YOLK_SAC_TUMOR 6233All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN 514319All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP 380213All SZGR genes in this pathway
JOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_DN 4535All SZGR genes in this pathway
KIM_MYCN_AMPLIFICATION_TARGETS_DN 10359All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4 261153All SZGR genes in this pathway
INGRAM_SHH_TARGETS_UP 12779All SZGR genes in this pathway
AMIT_SERUM_RESPONSE_40_MCF10A 3221All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_UP 256159All SZGR genes in this pathway
JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP 7151All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP 157105All SZGR genes in this pathway
ABBUD_LIF_SIGNALING_2_UP 1413All SZGR genes in this pathway
ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP 2622All SZGR genes in this pathway
GERY_CEBP_TARGETS 12690All SZGR genes in this pathway
IGLESIAS_E2F_TARGETS_UP 151103All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP 390242All SZGR genes in this pathway
RUAN_RESPONSE_TO_TNF_UP 1210All SZGR genes in this pathway
CUI_TCF21_TARGETS_UP 3727All SZGR genes in this pathway
SIMBULAN_PARP1_TARGETS_UP 3123All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_UP 428266All SZGR genes in this pathway
WANG_SMARCE1_TARGETS_UP 280183All SZGR genes in this pathway
URS_ADIPOCYTE_DIFFERENTIATION_DN 3020All SZGR genes in this pathway
JI_CARCINOGENESIS_BY_KRAS_AND_STK11_DN 1712All SZGR genes in this pathway
MCCABE_BOUND_BY_HOXC6 469239All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_DN 191123All SZGR genes in this pathway
MCCABE_HOXC6_TARGETS_DN 2115All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
BOQUEST_STEM_CELL_UP 260174All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
LABBE_TGFB1_TARGETS_DN 10864All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_DN 546362All SZGR genes in this pathway
BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_DN 12775All SZGR genes in this pathway
SCHRAETS_MLL_TARGETS_UP 3521All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_DN 2911All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_DN 210141All SZGR genes in this pathway
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP 7646All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN 207139All SZGR genes in this pathway
CHICAS_RB1_TARGETS_GROWING 243155All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP 504321All SZGR genes in this pathway
KIM_GLIS2_TARGETS_UP 8461All SZGR genes in this pathway
ZHU_SKIL_TARGETS_UP 2014All SZGR genes in this pathway
BAKKER_FOXO3_TARGETS_UP 6141All SZGR genes in this pathway
BRIDEAU_IMPRINTED_GENES 6347All SZGR genes in this pathway
ANASTASSIOU_CANCER_MESENCHYMAL_TRANSITION_SIGNATURE 6440All SZGR genes in this pathway
DURAND_STROMA_NS_UP 162103All SZGR genes in this pathway
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR 12873All SZGR genes in this pathway
NABA_PROTEOGLYCANS 3523All SZGR genes in this pathway
NABA_CORE_MATRISOME 275148All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-376c4684741Ahsa-miR-376cAACAUAGAGGAAAUUCCACG
miR-4964704761Ahsa-miR-496AUUACAUGGCCAAUCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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