Gene Page: DDX11

Summary
GeneID  1663
Symbol  DDX11
Synonyms  CHL1|CHLR1|KRG2|MGC133249|MGC9335
Description  DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)
See related  HGNC:2736|MIM:601150|Ensembl:ENSG00000013573|HPRD:03095|
Locus tag  -
Gene type  protein-coding
Map location  12p11
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.975 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
AP001362.10.710.71
EHBP1L10.710.70
MESP10.710.71
C7orf500.670.63
HBQ10.670.70
MAGIX0.670.64
PPM1M0.660.70
FAM98C0.660.65
LIN7B0.660.62
HSD11B1L0.660.64
Top 10 negatively co-expressed genes
LIMCH1-0.35-0.30
C6orf204-0.34-0.32
ITSN1-0.34-0.31
ZNF652-0.33-0.33
RAI14-0.33-0.28
NFIA-0.33-0.26
FAM59A-0.33-0.23
C8orf79-0.33-0.22
KIF5B-0.32-0.32
FEM1C-0.32-0.28
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003677DNA bindingIEA-
GO:0003723RNA bindingIEA-
GO:0004003ATP-dependent DNA helicase activityIEA-
GO:0005524ATP bindingIEA-
GO:0016787hydrolase activityIEA-
GO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000070mitotic sister chromatid segregationTAS9013641 
GO:0000084S phase of mitotic cell cycleTAS9013641 
GO:0000086G2/M transition of mitotic cell cycleTAS9013641 
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic processIEA-
GO:0007049cell cycleIEA-
GO:0008284positive regulation of cell proliferationTAS9013641 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005730nucleolusTAS9013641 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MYST2HBO1 | HBOA | KAT7MYST histone acetyltransferase 2Two-hybridBioGRID16169070 
PFN2D3S1319E | PFLprofilin 2Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_DIABETES_PATHWAYS 13391All SZGR genes in this pathway
REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S 4634All SZGR genes in this pathway
REACTOME_UNFOLDED_PROTEIN_RESPONSE 8051All SZGR genes in this pathway
KORKOLA_YOLK_SAC_TUMOR_UP 2014All SZGR genes in this pathway
LIU_SOX4_TARGETS_DN 309191All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
HORIUCHI_WTAP_TARGETS_DN 310188All SZGR genes in this pathway
NOJIMA_SFRP2_TARGETS_DN 2518All SZGR genes in this pathway
WANG_CLIM2_TARGETS_UP 269146All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN 335193All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN 180101All SZGR genes in this pathway
MAYBURD_RESPONSE_TO_L663536_DN 5632All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_BRCA2_PCC_NETWORK 423265All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN 10364All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_DN 160110All SZGR genes in this pathway
MANALO_HYPOXIA_DN 289166All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_UP 202115All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
LIN_MELANOMA_COPY_NUMBER_UP 7353All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN 270181All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
FOURNIER_ACINAR_DEVELOPMENT_LATE_2 277172All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_DN 3720All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP 570339All SZGR genes in this pathway


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