Gene Page: DES

Summary
GeneID  1674
Symbol  DES
Synonyms  CMD1I|CSM1|CSM2|FLJ12025|FLJ39719|FLJ41013|FLJ41793
Description  desmin
See related  HGNC:2770|MIM:125660|Ensembl:ENSG00000175084|HPRD:00514|
Locus tag  -
Gene type  protein-coding
Map location  2q35
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00916 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01016 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
GO:0005200structural constituent of cytoskeletonTAS9736733 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007010cytoskeleton organizationTAS9736733 
GO:0008016regulation of heart contractionTAS9697706 
GO:0006936muscle contractionTAS9697706 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0005856cytoskeletonIEA-
GO:0005882intermediate filamentTAS9736733 
GO:0005626insoluble fractionIEA-
GO:0005737cytoplasmIEA-
GO:0030018Z discIDA9415431 
GO:0042383sarcolemmaIEA-
GO:0043292contractile fiberIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CAPN1CANP | CANP1 | CANPL1 | muCANP | muCLcalpain 1, (mu/I) large subunitCAPN1 interacts with DES.BIND12358155 
DSPDPI | DPIIdesmoplakin-HPRD,BioGRID9261168 
NEBDKFZp686C1456 | FLJ11505 | FLJ36536 | FLJ39568 | FLJ39584 | NEB177D | NEM2nebulinTwo-hybridBioGRID11309420 
S100A1S100 | S100-alpha | S100AS100 calcium binding protein A1-HPRD,BioGRID8641565 
S100BNEF | S100 | S100betaS100 calcium binding protein B-HPRD10510252 
SPTAN1(ALPHA)II-SPECTRIN | FLJ44613 | NEASspectrin, alpha, non-erythrocytic 1 (alpha-fodrin)-HPRD,BioGRID2939097 
SYNCMGC149625 | MGC149626 | SYNC1 | SYNCOILINsyncoilin, intermediate filament protein-HPRD,BioGRID11694502 
SYNMDMN | KIAA0353 | SYNsynemin, intermediate filament protein-HPRD,BioGRID11353857 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM 8565All SZGR genes in this pathway
KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC 7659All SZGR genes in this pathway
KEGG_DILATED_CARDIOMYOPATHY 9268All SZGR genes in this pathway
PID_AURORA_B_PATHWAY 3924All SZGR genes in this pathway
REACTOME_STRIATED_MUSCLE_CONTRACTION 2712All SZGR genes in this pathway
REACTOME_MUSCLE_CONTRACTION 4824All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
WILCOX_RESPONSE_TO_PROGESTERONE_DN 6644All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP 207128All SZGR genes in this pathway
HUMMERICH_SKIN_CANCER_PROGRESSION_DN 10064All SZGR genes in this pathway
EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION 5026All SZGR genes in this pathway
OHASHI_AURKB_TARGETS 106All SZGR genes in this pathway
SCHLESINGER_H3K27ME3_IN_NORMAL_AND_METHYLATED_IN_CANCER 2821All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_F 5432All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_UP 9864All SZGR genes in this pathway
KAYO_CALORIE_RESTRICTION_MUSCLE_UP 9564All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
WEST_ADRENOCORTICAL_CARCINOMA_VS_ADENOMA_UP 2113All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED 536296All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3_UNMETHYLATED 3721All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
ZEMBUTSU_SENSITIVITY_TO_CISPLATIN 2014All SZGR genes in this pathway
ZEMBUTSU_SENSITIVITY_TO_DOXORUBICIN 1710All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_C 9260All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN 308187All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-3705775831Ahsa-miR-370brainGCCUGCUGGGGUGGAACCUGG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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