Gene Page: ENO1

Summary
GeneID  2023
Symbol  ENO1
Synonyms  ENO1L1|MBP-1|MPB1|NNE|PPH
Description  enolase 1, (alpha)
See related  HGNC:3350|MIM:172430|Ensembl:ENSG00000074800|HPRD:01400|
Locus tag  -
Gene type  protein-coding
Map location  1p36.3-p36.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ALAS20.930.83
SLC4A10.920.81
HBG10.890.78
HEMGN0.880.79
HBM0.880.76
ERAF0.870.83
HBA10.850.79
HBA20.840.74
NFE20.830.60
GATA10.790.50
Top 10 negatively co-expressed genes
C5orf53-0.47-0.71
FBXO2-0.47-0.68
HLA-F-0.46-0.65
CCNI2-0.46-0.69
AIFM3-0.45-0.65
CA4-0.44-0.66
AF347015.27-0.44-0.69
S100B-0.43-0.67
BCL2L2-0.43-0.64
AF347015.33-0.43-0.70
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityIEAglutamate (GO term level: 7)-
GO:0000287magnesium ion bindingIEA-
GO:0003700transcription factor activityTAS2005901 
GO:0003714transcription corepressor activityTAS2005901 
GO:0004634phosphopyruvate hydratase activityTAS3529090 
GO:0005515protein bindingIPI11134351 
GO:0016829lyase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000122negative regulation of transcription from RNA polymerase II promoterTAS2005901 
GO:0006350transcriptionIEA-
GO:0006096glycolysisIEA-
GO:0030308negative regulation of cell growthIDA10082554 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000015phosphopyruvate hydratase complexIEA-
GO:0005634nucleusIC10082554 
GO:0005737cytoplasmIEA-
GO:0005886plasma membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
FANCAFA | FA-H | FA1 | FAA | FACA | FAH | FANCH | MGC75158Fanconi anemia, complementation group ATwo-hybridBioGRID14499622 
MAP3K7TAK1 | TGF1amitogen-activated protein kinase kinase kinase 7-HPRD14743216 
PLGDKFZp779M0222plasminogenReconstituted ComplexBioGRID11169399 
TRAPPC2MIP-2A | SEDL | SEDT | TRS20 | ZNF547L | hYP38334trafficking protein particle complex 2Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID11134351 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_GLYCOLYSIS_GLUCONEOGENESIS 6241All SZGR genes in this pathway
KEGG_RNA_DEGRADATION 5937All SZGR genes in this pathway
BIOCARTA_GLYCOLYSIS_PATHWAY 109All SZGR genes in this pathway
PID_NOTCH_PATHWAY 5949All SZGR genes in this pathway
PID_MYC_ACTIV_PATHWAY 7962All SZGR genes in this pathway
PID_HIF1_TFPATHWAY 6652All SZGR genes in this pathway
REACTOME_GLYCOLYSIS 2918All SZGR genes in this pathway
REACTOME_GLUCONEOGENESIS 3421All SZGR genes in this pathway
REACTOME_METABOLISM_OF_CARBOHYDRATES 247154All SZGR genes in this pathway
REACTOME_GLUCOSE_METABOLISM 6942All SZGR genes in this pathway
LIU_SOX4_TARGETS_DN 309191All SZGR genes in this pathway
PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP 8251All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_UP 430232All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_UP 404246All SZGR genes in this pathway
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN 362238All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_UP 380236All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP 418263All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_UP 14296All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_UP 162104All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_UP 147101All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP 146104All SZGR genes in this pathway
HUMMERICH_SKIN_CANCER_PROGRESSION_UP 8858All SZGR genes in this pathway
LI_AMPLIFIED_IN_LUNG_CANCER 178108All SZGR genes in this pathway
MATTIOLI_MGUS_VS_PCL 11662All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_VIA_SMAD4_UP 10866All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_UP 201127All SZGR genes in this pathway
KIM_MYCN_AMPLIFICATION_TARGETS_UP 9264All SZGR genes in this pathway
TSAI_RESPONSE_TO_IONIZING_RADIATION 149101All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_DN 156106All SZGR genes in this pathway
GROSS_HIF1A_TARGETS_DN 2515All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_HIF1A_DN 11078All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
CAFFAREL_RESPONSE_TO_THC_8HR_3_DN 107All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX 230156All SZGR genes in this pathway
MORI_SMALL_PRE_BII_LYMPHOCYTE_DN 7652All SZGR genes in this pathway
TCGA_GLIOBLASTOMA_COPY_NUMBER_DN 3121All SZGR genes in this pathway
MENSSEN_MYC_TARGETS 5335All SZGR genes in this pathway
FERNANDEZ_BOUND_BY_MYC 182116All SZGR genes in this pathway
POMEROY_MEDULLOBLASTOMA_PROGNOSIS_DN 4328All SZGR genes in this pathway
SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP 4530All SZGR genes in this pathway
KANG_IMMORTALIZED_BY_TERT_UP 8961All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_METHOTREXATE_DN 2719All SZGR genes in this pathway
MODY_HIPPOCAMPUS_POSTNATAL 6350All SZGR genes in this pathway
HARRIS_HYPOXIA 8164All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_UP 8648All SZGR genes in this pathway
LEE_AGING_MUSCLE_DN 4629All SZGR genes in this pathway
ZHU_CMV_ALL_UP 12089All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN 4631All SZGR genes in this pathway
ZHU_CMV_24_HR_UP 9365All SZGR genes in this pathway
SEMENZA_HIF1_TARGETS 3632All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE 7750All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM 6647All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST 13293All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_T7 9863All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP 180114All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN 315197All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
HONMA_DOCETAXEL_RESISTANCE 3423All SZGR genes in this pathway
WHITEFORD_PEDIATRIC_CANCER_MARKERS 11663All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_UP 294199All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_DN 342220All SZGR genes in this pathway
WINTER_HYPOXIA_METAGENE 242168All SZGR genes in this pathway
ALONSO_METASTASIS_UP 198128All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_UP 374247All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_UP 212128All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_DN 240153All SZGR genes in this pathway
HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP 163102All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES 389245All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP 188121All SZGR genes in this pathway
NGO_MALIGNANT_GLIOMA_1P_LOH 1713All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
DANG_MYC_TARGETS_UP 143100All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
WONG_EMBRYONIC_STEM_CELL_CORE 335193All SZGR genes in this pathway
MOOTHA_GLUCONEOGENESIS 3223All SZGR genes in this pathway
MOOTHA_GLYCOLYSIS 2113All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1 2821All SZGR genes in this pathway
LI_DCP2_BOUND_MRNA 8957All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE 15186All SZGR genes in this pathway


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