Gene Page: ENO2

Summary
GeneID  2026
Symbol  ENO2
Synonyms  NSE
Description  enolase 2 (gamma, neuronal)
See related  HGNC:3353|MIM:131360|Ensembl:ENSG00000111674|HPRD:00573|
Locus tag  -
Gene type  protein-coding
Map location  12p13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
FOXP20.880.42
LHX90.870.19
FIGN0.870.34
TRPM80.850.31
TCF7L20.850.22
ANO20.840.26
GBX20.840.25
FAM83G0.840.31
TRH0.830.19
MAP4K10.810.23
Top 10 negatively co-expressed genes
GTDC1-0.200.09
JAM2-0.200.02
RGS20-0.20-0.28
PIK3IP1-0.200.04
COX4I2-0.20-0.32
AIF1L-0.20-0.23
CKB-0.190.02
PPP2R5A-0.19-0.02
SLC26A4-0.190.02
ARSF-0.19-0.19
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000287magnesium ion bindingIEA-
GO:0004634phosphopyruvate hydratase activityTAS2045099 
GO:0016829lyase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006096glycolysisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000015phosphopyruvate hydratase complexIEA-
GO:0005737cytoplasmIEA-
GO:0005886plasma membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ANXA11ANX11 | CAP50annexin A11Two-hybridBioGRID16169070 
C16orf45FLJ32618chromosome 16 open reading frame 45Two-hybridBioGRID16169070 
C6orf47D6S53E | G4 | NG34chromosome 6 open reading frame 47Two-hybridBioGRID16169070 
ENSAMGC4319 | MGC78563 | MGC8394endosulfine alphaTwo-hybridBioGRID16169070 
HABP4IHABP4 | Ki-1/57 | MGC825 | SERBP1Lhyaluronan binding protein 4Two-hybridBioGRID16169070 
HK1HK1-ta | HK1-tb | HK1-tc | HKI | HXK1hexokinase 1Two-hybridBioGRID16169070 
HSF1HSTF1heat shock transcription factor 1Two-hybridBioGRID16169070 
IL17BIL-17B | IL-20 | MGC138900 | MGC138901 | ZCYTO7interleukin 17BTwo-hybridBioGRID16169070 
MAP4DKFZp779A1753 | MGC8617microtubule-associated protein 4Two-hybridBioGRID16169070 
NAT9DKFZp564C103 | EBSPN-acetyltransferase 9 (GCN5-related, putative)Two-hybridBioGRID16169070 
NDUFS7CI-20KD | FLJ45860 | FLJ46880 | MGC120002 | MY017 | PSSTNADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)Two-hybridBioGRID16169070 
SIGIRRMGC110992 | TIR8single immunoglobulin and toll-interleukin 1 receptor (TIR) domainTwo-hybridBioGRID16169070 
SNUPNKPNBL | RNUT1 | Snurportin1snurportin 1Two-hybridBioGRID16169070 
ST3GAL2Gal-NAc6S | SIAT4B | ST3GALII | ST3GalA.2ST3 beta-galactoside alpha-2,3-sialyltransferase 2Two-hybridBioGRID16169070 
TUBA4AFLJ30169 | H2-ALPHA | TUBA1tubulin, alpha 4aTwo-hybridBioGRID16169070 
UBE2CUBCH10 | dJ447F3.2ubiquitin-conjugating enzyme E2CTwo-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_GLYCOLYSIS_GLUCONEOGENESIS 6241All SZGR genes in this pathway
KEGG_RNA_DEGRADATION 5937All SZGR genes in this pathway
REACTOME_GLYCOLYSIS 2918All SZGR genes in this pathway
REACTOME_GLUCONEOGENESIS 3421All SZGR genes in this pathway
REACTOME_METABOLISM_OF_CARBOHYDRATES 247154All SZGR genes in this pathway
REACTOME_GLUCOSE_METABOLISM 6942All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
KORKOLA_EMBRYONAL_CARCINOMA_UP 4127All SZGR genes in this pathway
KORKOLA_SEMINOMA_UP 4427All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP 183119All SZGR genes in this pathway
GARY_CD5_TARGETS_UP 473314All SZGR genes in this pathway
HOOI_ST7_TARGETS_DN 12378All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
DOANE_RESPONSE_TO_ANDROGEN_DN 241146All SZGR genes in this pathway
KIM_WT1_TARGETS_UP 214155All SZGR genes in this pathway
KIM_WT1_TARGETS_8HR_UP 164122All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_UP 162116All SZGR genes in this pathway
ELVIDGE_HYPOXIA_UP 171112All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_UP 13085All SZGR genes in this pathway
ELVIDGE_HIF1A_TARGETS_DN 9158All SZGR genes in this pathway
ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN 10472All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP 12073All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN 234147All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN 8454All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
KAN_RESPONSE_TO_ARSENIC_TRIOXIDE 12380All SZGR genes in this pathway
TOMIDA_METASTASIS_DN 1811All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL 326213All SZGR genes in this pathway
MAINA_VHL_TARGETS_DN 1814All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_HIF1A_DN 11078All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP 142104All SZGR genes in this pathway
LIAO_METASTASIS 539324All SZGR genes in this pathway
WOTTON_RUNX_TARGETS_DN 2918All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_UP 256159All SZGR genes in this pathway
ROZANOV_MMP14_TARGETS_UP 266171All SZGR genes in this pathway
STANELLE_E2F1_TARGETS 2920All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
MANALO_HYPOXIA_UP 207145All SZGR genes in this pathway
PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN 162102All SZGR genes in this pathway
MENSE_HYPOXIA_UP 9871All SZGR genes in this pathway
NAKAJIMA_MAST_CELL 4634All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_DN 5235All SZGR genes in this pathway
KIM_HYPOXIA 2521All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_16HR_UP 225139All SZGR genes in this pathway
MODY_HIPPOCAMPUS_POSTNATAL 6350All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
JIANG_VHL_TARGETS 13891All SZGR genes in this pathway
LINDVALL_IMMORTALIZED_BY_TERT_DN 8056All SZGR genes in this pathway
ZHU_CMV_ALL_UP 12089All SZGR genes in this pathway
MOREIRA_RESPONSE_TO_TSA_UP 2823All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
ZHU_CMV_24_HR_UP 9365All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
BILD_E2F3_ONCOGENIC_SIGNATURE 246153All SZGR genes in this pathway
COATES_MACROPHAGE_M1_VS_M2_UP 8152All SZGR genes in this pathway
OUILLETTE_CLL_13Q14_DELETION_DN 6038All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_DN 249165All SZGR genes in this pathway
HUPER_BREAST_BASAL_VS_LUMINAL_DN 5944All SZGR genes in this pathway
CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN 10265All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
WOO_LIVER_CANCER_RECURRENCE_UP 10575All SZGR genes in this pathway
KOBAYASHI_EGFR_SIGNALING_24HR_DN 251151All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP 8750All SZGR genes in this pathway
MOOTHA_GLUCONEOGENESIS 3223All SZGR genes in this pathway
MOOTHA_GLYCOLYSIS 2113All SZGR genes in this pathway
JIANG_HYPOXIA_VIA_VHL 3424All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
DUAN_PRDM5_TARGETS 7952All SZGR genes in this pathway
WACKER_HYPOXIA_TARGETS_OF_VHL 1311All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
ROESSLER_LIVER_CANCER_METASTASIS_UP 10772All SZGR genes in this pathway
ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF 516308All SZGR genes in this pathway


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