Gene Page: EPB41L1

Summary
GeneID  2036
Symbol  EPB41L1
Synonyms  4.1N|DKFZp686H17242|KIAA0338|MGC11072
Description  erythrocyte membrane protein band 4.1-like 1
See related  HGNC:3378|MIM:602879|Ensembl:ENSG00000088367|HPRD:04193|
Locus tag  RP11-234K24.1
Gene type  protein-coding
Map location  20q11.2-q12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.5394 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TRPV60.840.89
KCNJ110.800.81
KCNQ40.800.81
DUSP70.790.84
GFRA20.780.80
CACNB10.780.80
KLC20.780.78
BAIAP20.770.81
POU6F10.760.78
AC021534.10.750.81
Top 10 negatively co-expressed genes
RAB13-0.51-0.61
AF347015.21-0.50-0.42
NSBP1-0.49-0.55
DBI-0.48-0.53
AP002478.3-0.47-0.49
GNG11-0.45-0.47
AL139819.3-0.45-0.45
MYL12A-0.44-0.50
AF347015.18-0.44-0.39
AF347015.31-0.43-0.37
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003779actin bindingIEA-
GO:0005488bindingIEA-
GO:0005198structural molecule activityIEA-
GO:0008092cytoskeletal protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030866cortical actin cytoskeleton organizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005856cytoskeletonIEA-
GO:0005737cytoplasmIEA-
GO:0019898extrinsic to membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AGAP2CENTG1 | FLJ16430 | GGAP2 | KIAA0167 | PIKEArfGAP with GTPase domain, ankyrin repeat and PH domain 2-HPRD,BioGRID11136977 
DRD2D2DR | D2Rdopamine receptor D2-HPRD,BioGRID12181426 
DRD3D3DR | ETM1 | FET1 | MGC149204 | MGC149205dopamine receptor D3-HPRD,BioGRID12181426 
GRIA1GLUH1 | GLUR1 | GLURA | HBGR1 | MGC133252glutamate receptor, ionotropic, AMPA 1-HPRD,BioGRID11050113 
GRIA4GLUR4 | GLUR4C | GLURDglutamate receptor, ionotrophic, AMPA 4-HPRD12574408 
ITPR1INSP3R1 | IP3R | IP3R1 | SCA15 | SCA16inositol 1,4,5-triphosphate receptor, type 1-HPRD,BioGRID12444087 |12676536 
NUMA1NUMAnuclear mitotic apparatus protein 1-HPRD,BioGRID10594058 
SDC2HSPG | HSPG1 | SYND2syndecan 2Affinity Capture-WesternBioGRID12676536 
STARD13DLC2 | FLJ37385 | GT650StAR-related lipid transfer (START) domain containing 13STARD13 (RhoGAP) interacts with EPB41L1 (KIAA0338).BIND14697242 
-HPRD,BioGRID14697242 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_TIGHT_JUNCTION 13486All SZGR genes in this pathway
PID_PI3K_PLC_TRK_PATHWAY 3631All SZGR genes in this pathway
REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 186155All SZGR genes in this pathway
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL 137110All SZGR genes in this pathway
REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS 2823All SZGR genes in this pathway
SCIBETTA_KDM5B_TARGETS_DN 8155All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT 10873All SZGR genes in this pathway
ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN 10364All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_20Q11_AMPLICON 3118All SZGR genes in this pathway
ASTIER_INTEGRIN_SIGNALING 5944All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 412249All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP 393244All SZGR genes in this pathway
LEIN_LOCALIZED_TO_DISTAL_AND_PROXIMAL_DENDRITES 1712All SZGR genes in this pathway
ZHENG_IL22_SIGNALING_DN 4226All SZGR genes in this pathway
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN 159105All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 196124All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 142103All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
KOBAYASHI_EGFR_SIGNALING_24HR_UP 10165All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
ZWANG_EGF_PERSISTENTLY_DN 6136All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101110116m8hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-128102510311Ahsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-14939451Ahsa-miR-149brainUCUGGCUCCGUGUCUUCACUCC
miR-18329232991A,m8hsa-miR-18aUAAGGUGCAUCUAGUGCAGAUA
hsa-miR-18bUAAGGUGCAUCUAGUGCAGUUA
miR-199630636m8hsa-miR-199aCCCAGUGUUCAGACUACCUGUUC
hsa-miR-199bCCCAGUGUUUAGACUAUCUGUUC
miR-21832243230m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-274101Ahsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-32641471Ahsa-miR-326CCUCUGGGCCCUUCCUCCAG
miR-334854911Ahsa-miR-33GUGCAUUGUAGUUGCAUUG
hsa-miR-33bGUGCAUUGCUGUUGCAUUGCA
miR-381341134181A,m8hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-4315325391A,m8hsa-miR-431UGUCUUGCAGGCCGUCAUGCA
miR-4861811871Ahsa-miR-486UCCUGUACUGAGCUGCCCCGAG
miR-494320232081Ahsa-miR-494brainUGAAACAUACACGGGAAACCUCUU
miR-500896902m8hsa-miR-500AUGCACCUGGGCAAGGAUUCUG
miR-542-3p113119m8hsa-miR-542-3pUGUGACAGAUUGAUAACUGAAA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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