Gene Page: AK3L1

Summary
GeneID  205
Symbol  AK3L1
Synonyms  AK3|AK4|MGC166959
Description  adenylate kinase 3-like 1
See related  HGNC:363|MIM:103030|Ensembl:ENSG00000162433|HPRD:00048|
Locus tag  RP4-686B20.1
Gene type  protein-coding
Map location  1p31.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02692 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
KIF70.880.83
PLCG10.860.81
BMP10.850.81
ABCD40.850.80
TTC310.850.82
SCRIB0.850.81
HAUS50.850.78
TTLL40.840.79
DVL20.840.80
CDAN10.840.82
Top 10 negatively co-expressed genes
AF347015.27-0.55-0.60
C5orf53-0.53-0.53
AF347015.31-0.53-0.58
AF347015.21-0.52-0.63
MT-CO2-0.51-0.57
AF347015.33-0.48-0.52
AF347015.8-0.48-0.55
MT-CYB-0.48-0.53
ACOT13-0.47-0.46
RERGL-0.46-0.60
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0004017adenylate kinase activityIEA-
GO:0005524ATP bindingIEA-
GO:0005525GTP bindingIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005739mitochondrionIEA-
GO:0005759mitochondrial matrixIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PURINE_METABOLISM 15996All SZGR genes in this pathway
WINTER_HYPOXIA_UP 9257All SZGR genes in this pathway
KORKOLA_EMBRYONAL_CARCINOMA_UP 4127All SZGR genes in this pathway
KORKOLA_SEMINOMA_UP 4427All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
CHANDRAN_METASTASIS_TOP50_UP 3827All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
GARY_CD5_TARGETS_DN 431263All SZGR genes in this pathway
PRAMOONJAGO_SOX4_TARGETS_UP 5238All SZGR genes in this pathway
LIU_CMYB_TARGETS_UP 165106All SZGR genes in this pathway
GRABARCZYK_BCL11B_TARGETS_UP 8140All SZGR genes in this pathway
BASAKI_YBX1_TARGETS_DN 384230All SZGR genes in this pathway
ELVIDGE_HYPOXIA_UP 171112All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_UP 13085All SZGR genes in this pathway
ELVIDGE_HIF1A_TARGETS_DN 9158All SZGR genes in this pathway
ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN 10472All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
PROVENZANI_METASTASIS_DN 13694All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP 12895All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN 7550All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN 172112All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
KAN_RESPONSE_TO_ARSENIC_TRIOXIDE 12380All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL 326213All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_BASAL 330217All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
SHEPARD_CRUSH_AND_BURN_MUTANT_UP 197110All SZGR genes in this pathway
SCHUHMACHER_MYC_TARGETS_UP 8057All SZGR genes in this pathway
COLLER_MYC_TARGETS_UP 2519All SZGR genes in this pathway
MANALO_HYPOXIA_UP 207145All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION 8868All SZGR genes in this pathway
VERHAAK_AML_WITH_NPM1_MUTATED_DN 246180All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_METHOTREXATE_DN 2719All SZGR genes in this pathway
LEONARD_HYPOXIA 4735All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN 4631All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_UP 1917All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_24HR_UP 14896All SZGR genes in this pathway
BILD_E2F3_ONCOGENIC_SIGNATURE 246153All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 307185All SZGR genes in this pathway
NAKAMURA_METASTASIS_MODEL_DN 4328All SZGR genes in this pathway
ALONSO_METASTASIS_UP 198128All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 456285All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_DN 277166All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
YAGI_AML_WITH_11Q23_REARRANGED 351238All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
WONG_EMBRYONIC_STEM_CELL_CORE 335193All SZGR genes in this pathway
CHANDRAN_METASTASIS_UP 221135All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_UP 217131All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN 229135All SZGR genes in this pathway
FARDIN_HYPOXIA_9 76All SZGR genes in this pathway
FARDIN_HYPOXIA_11 3229All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1403833891Ahsa-miR-140brainAGUGGUUUUACCCUAUGGUAG
miR-141/200a10631069m8hsa-miR-141UAACACUGUCUGGUAAAGAUGG
hsa-miR-200aUAACACUGUCUGGUAACGAUGU
miR-15/16/195/424/497104110481A,m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-503104210481Ahsa-miR-503UAGCAGCGGGAACAGUUCUGCAG
miR-9122312291Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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