Gene Page: F7

Summary
GeneID  2155
Symbol  F7
Synonyms  -
Description  coagulation factor VII (serum prothrombin conversion accelerator)
See related  HGNC:3544|MIM:227500|Ensembl:ENSG00000057593|HPRD:01965|
Locus tag  -
Gene type  protein-coding
Map location  13q34
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
GNG30.780.83
STX1A0.770.85
CAMK10.750.82
NPM20.750.84
PNOC0.740.82
LEPREL20.740.85
TCEAL10.740.82
PRKCZ0.730.81
STK32C0.730.83
SNCA0.720.78
Top 10 negatively co-expressed genes
PLXNB1-0.42-0.42
PXN-0.41-0.42
RAB13-0.40-0.49
GPR125-0.40-0.39
REST-0.39-0.37
CASKIN2-0.39-0.40
GRTP1-0.38-0.40
EPHA2-0.38-0.41
SORBS3-0.37-0.39
TP53BP2-0.37-0.33
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityIEAglutamate (GO term level: 7)-
GO:0004252serine-type endopeptidase activityTASglutamate (GO term level: 7)3037537 
GO:0003824catalytic activityIEA-
GO:0005509calcium ion bindingIEA-
GO:0005515protein bindingIPI18267072 
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
GO:0007598blood coagulation, extrinsic pathwayEXP7598447 
GO:0007596blood coagulationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionEXP3527261 |8598903 |8639673 
GO:0005576extracellular regionIEA-
GO:0005576extracellular regionTAS3037537 
GO:0005886plasma membraneEXP2271516 |3527261 |8598903 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
F10FX | FXAcoagulation factor X-HPRD,BioGRID11560488 
F3CD142 | TF | TFAcoagulation factor III (thromboplastin, tissue factor)-HPRD9925787|12787023 
Co-crystal Structure
Reconstituted Complex		BioGRID9925787 |12787023 
F7-coagulation factor VII (serum prothrombin conversion accelerator)-HPRD8598903 |9925787 
|10430872 |10544046 
|11470437 
F9FIX | HEMB | MGC129641 | MGC129642 | PTCcoagulation factor IX-HPRD2248955 
IKBKGAMCBX1 | FIP-3 | FIP3 | Fip3p | IKK-gamma | IP | IP1 | IP2 | IPD2 | NEMOinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma-HPRD14743216 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_COMPLEMENT_AND_COAGULATION_CASCADES 6949All SZGR genes in this pathway
BIOCARTA_AMI_PATHWAY 2013All SZGR genes in this pathway
BIOCARTA_EXTRINSIC_PATHWAY 139All SZGR genes in this pathway
REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION 2717All SZGR genes in this pathway
REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION 3627All SZGR genes in this pathway
REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS 118All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE 3222All SZGR genes in this pathway
REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 188116All SZGR genes in this pathway
REACTOME_CIRCADIAN_CLOCK 5340All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP 380215All SZGR genes in this pathway
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP 233161All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_5 14789All SZGR genes in this pathway
XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_DN 2717All SZGR genes in this pathway
LIU_COMMON_CANCER_GENES 7947All SZGR genes in this pathway
SHEPARD_BMYB_MORPHOLINO_DN 200112All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
HSIAO_LIVER_SPECIFIC_GENES 244154All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 412249All SZGR genes in this pathway
ZHU_CMV_24_HR_DN 9164All SZGR genes in this pathway
ZHU_CMV_ALL_DN 12893All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_UP 202115All SZGR genes in this pathway
STEARMAN_TUMOR_FIELD_EFFECT_UP 3622All SZGR genes in this pathway
STEARMAN_LUNG_CANCER_EARLY_VS_LATE_DN 6139All SZGR genes in this pathway
COATES_MACROPHAGE_M1_VS_M2_DN 7844All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_UP 170107All SZGR genes in this pathway
CHENG_IMPRINTED_BY_ESTRADIOL 11068All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_DN 540340All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN 13892All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G3_DN 5132All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION 422277All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
VANLOO_SP3_TARGETS_DN 8947All SZGR genes in this pathway
RATTENBACHER_BOUND_BY_CELF1 467251All SZGR genes in this pathway
NABA_ECM_REGULATORS 238125All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway


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