Gene Page: DIS3

Summary
GeneID  22894
Symbol  DIS3
Synonyms  DKFZp667L1817|EXOSC11|FLJ10484|KIAA1008|MGC33035|RP11-342J4.3|RRP44|bA555G22.1|dis3p
Description  DIS3 mitotic control homolog (S. cerevisiae)
See related  HGNC:20604|MIM:607533|Ensembl:ENSG00000083520|HPRD:06338|
Locus tag  -
Gene type  protein-coding
Map location  13q22.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
AC145098.20.970.96
RALGDS0.950.93
ANKRD13B0.950.96
KIAA0895L0.950.97
PLXNA30.950.94
ZNF4460.950.93
LMBR1L0.940.93
CCDC1200.940.95
FGD10.940.96
CUL70.930.96
Top 10 negatively co-expressed genes
AF347015.31-0.75-0.88
AF347015.27-0.75-0.88
MT-CO2-0.74-0.88
AF347015.33-0.72-0.85
S100B-0.72-0.83
C5orf53-0.72-0.74
HLA-F-0.71-0.73
MT-CYB-0.71-0.85
AF347015.8-0.71-0.87
COPZ2-0.70-0.80
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003723RNA bindingIEA-
GO:0005515protein bindingIPI15231747 
GO:0004540ribonuclease activityIEA-
GO:0004527exonuclease activityIEA-
GO:0016787hydrolase activityIEA-
GO:0016219GDP-dissociation stimulator activityIDA9562621 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006364rRNA processingTAS9562621 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000178exosome (RNase complex)TAS9562621 
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EXOSC1CGI-108 | CSL4 | Csl4p | SKI4 | Ski4p | hCsl4p | p13exosome component 1-HPRD12419256 
EXOSC3CGI-102 | MGC15120 | MGC723 | RP11-3J10.8 | RRP40 | Rrp40p | bA3J10.7 | hRrp40p | p10exosome component 3-HPRD12419256 
ZBTB17MIZ-1 | ZNF151 | ZNF60 | pHZ-67zinc finger and BTB domain containing 17-HPRD,BioGRID15231747 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_RNA_DEGRADATION 5937All SZGR genes in this pathway
REACTOME_DIABETES_PATHWAYS 13391All SZGR genes in this pathway
REACTOME_PERK_REGULATED_GENE_EXPRESSION 2914All SZGR genes in this pathway
REACTOME_ACTIVATION_OF_GENES_BY_ATF4 2612All SZGR genes in this pathway
REACTOME_UNFOLDED_PROTEIN_RESPONSE 8051All SZGR genes in this pathway
REACTOME_METABOLISM_OF_MRNA 284128All SZGR genes in this pathway
REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE 115All SZGR genes in this pathway
REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY 4829All SZGR genes in this pathway
REACTOME_METABOLISM_OF_RNA 330155All SZGR genes in this pathway
REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 179All SZGR genes in this pathway
REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS 8450All SZGR genes in this pathway
REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP 179All SZGR genes in this pathway
REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP 177All SZGR genes in this pathway
LIU_SOX4_TARGETS_DN 309191All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_DN 406230All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP 769437All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_DN 12986All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_10HR_UP 10169All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN 271175All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION 8865All SZGR genes in this pathway
KYNG_DNA_DAMAGE_UP 226164All SZGR genes in this pathway
ZHANG_TLX_TARGETS_36HR_DN 185116All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_DN 277166All SZGR genes in this pathway
ZHANG_TLX_TARGETS_DN 8950All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G1_S 14776All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway


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