Gene Page: PAXIP1

Summary
GeneID  22976
Symbol  PAXIP1
Synonyms  CAGF28|CAGF29|FLJ41049|PACIP1|PAXIP1L|PTIP|TNRC2
Description  PAX interacting (with transcription-activation domain) protein 1
See related  HGNC:8624|MIM:608254|HPRD:08491|
Locus tag  -
Gene type  protein-coding
Map location  7q36
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ABR0.930.92
PIP5K1C0.910.90
PITPNM20.900.90
SCAMP50.890.87
OSBP20.890.89
PVRL10.890.89
PCNXL20.880.86
CLSTN10.870.85
FBXO100.870.86
CACNB10.870.87
Top 10 negatively co-expressed genes
GNG11-0.54-0.57
AL139819.3-0.53-0.53
AF347015.21-0.53-0.48
C1orf54-0.52-0.55
AP002478.3-0.51-0.52
DBI-0.50-0.55
AF347015.31-0.48-0.45
AL138743.2-0.48-0.50
C1orf61-0.48-0.53
HIGD1B-0.47-0.44
Gene Ontology
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005634nucleusIEA-
GO:0016020membraneIEA-
GO:0031965nuclear membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
NUPR1COM1 | P8nuclear protein 1p8 interacts with PTIP.BIND11940591 
PAX2-paired box 2-HPRD,BioGRID10908331 
TP53BP153BP1 | FLJ41424 | MGC138366 | p202tumor protein p53 binding protein 1Affinity Capture-Western
Reconstituted Complex		BioGRID14576432 |15456759 
ZBTB8BOZF1 | FLJ90065 | MGC17919zinc finger and BTB domain containing 8Two-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN 234147All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN 8454All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
AMUNDSON_RESPONSE_TO_ARSENITE 217143All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_DN 9751All SZGR genes in this pathway
PUJANA_XPRSS_INT_NETWORK 168103All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_BRCA2_PCC_NETWORK 423265All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_DN 411249All SZGR genes in this pathway
SHEPARD_BMYB_MORPHOLINO_DN 200112All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN 2515All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN 353226All SZGR genes in this pathway
PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_DN 95All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-299-3p230236m8hsa-miR-299-3pUAUGUGGGAUGGUAAACCGCUU
miR-369-3p2102171A,m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-374211217m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-490257263m8hsa-miR-490CAACCUGGAGGACUCCAUGCUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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