Gene Page: SORCS3

Summary
GeneID  22986
Symbol  SORCS3
Synonyms  SORCS
Description  sortilin-related VPS10 domain containing receptor 3
See related  HGNC:16699|MIM:606285|Ensembl:ENSG00000156395|HPRD:12100|
Locus tag  RP11-107L7.1
Gene type  protein-coding
Map location  10q23-q25
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TRIM240.910.91
CHST100.900.90
ZNF4800.890.84
EML40.880.91
C20orf740.880.90
KDM5B0.880.91
ATF7IP0.880.90
NONO0.880.90
ALDH18A10.880.90
PRRC10.880.89
Top 10 negatively co-expressed genes
C5orf53-0.66-0.76
HLA-F-0.64-0.75
AF347015.27-0.63-0.85
FXYD1-0.63-0.84
S100B-0.62-0.79
AF347015.31-0.62-0.83
TSC22D4-0.62-0.76
MT-CO2-0.62-0.85
AF347015.33-0.62-0.82
SLC16A11-0.62-0.65
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008188neuropeptide receptor activityNASNeurotransmitter (GO term level: 8)11499680 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007218neuropeptide signaling pathwayNASNeurotransmitter (GO term level: 8)11499680 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneNAS11499680 
GO:0016021integral to membraneIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_SIGNALLING_BY_NGF 217167All SZGR genes in this pathway
REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 8161All SZGR genes in this pathway
CHEBOTAEV_GR_TARGETS_DN 12073All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_18HR_UP 178111All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
LIN_NPAS4_TARGETS_DN 6848All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_IPS_WITH_HCP_H3K27ME3 10276All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101180218081Ahsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-14417641770m8hsa-miR-144UACAGUAUAGAUGAUGUACUAG
hsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-30-5p100106m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-342157815841Ahsa-miR-342brainUCUCACACAGAAAUCGCACCCGUC
miR-346168516921A,m8hsa-miR-346brainUGUCUGCCCGCAUGCCUGCCUCU
miR-38212841290m8hsa-miR-382brainGAAGUUGUUCGUGGUGGAUUCG
miR-493-5p17561762m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-4965445501Ahsa-miR-496AUUACAUGGCCAAUCUC
miR-505183318391Ahsa-miR-505GUCAACACUUGCUGGUUUCCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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