Gene Page: XPO7

Summary
GeneID  23039
Symbol  XPO7
Synonyms  KIAA0745|RANBP16
Description  exportin 7
See related  HGNC:14108|MIM:606140|Ensembl:ENSG00000130227|HPRD:05846|
Locus tag  -
Gene type  protein-coding
Map location  8p21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.031 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.03086 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.00057 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SCN3A0.910.92
NAV30.900.92
SOS10.900.93
ACACA0.900.92
MAP3K7IP30.900.93
USP340.890.93
B4GALT50.890.91
C5orf420.880.91
KCTD100.880.92
MGEA50.880.93
Top 10 negatively co-expressed genes
MT-CO2-0.70-0.81
AF347015.31-0.70-0.79
FXYD1-0.69-0.77
IFI27-0.68-0.77
HIGD1B-0.68-0.81
S100B-0.67-0.74
AF347015.33-0.66-0.73
AC021016.1-0.66-0.76
HSD17B14-0.66-0.72
AF347015.27-0.66-0.74
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005049nuclear export signal receptor activityIDA11024021 
GO:0005488bindingIEA-
GO:0008565protein transporter activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000059protein import into nucleus, dockingIEA-
GO:0006611protein export from nucleusIDA11024021 
GO:0006886intracellular protein transportIEA-
GO:0051028mRNA transportIEA-
GO:0065002intracellular protein transmembrane transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA11071879 
GO:0005634nucleusIEA-
GO:0005643nuclear poreIDA11024021 
GO:0005643nuclear poreIEA-
GO:0005737cytoplasmIDA11071879 
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BRF2BRFU | FLJ11052 | TFIIIB50BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-likeAffinity Capture-MSBioGRID17353931 
C20orf24PNAS-11 | RIP5chromosome 20 open reading frame 24Affinity Capture-MSBioGRID17353931 
DDX19BDBP5 | DDX19 | RNAhDEAD (Asp-Glu-Ala-As) box polypeptide 19BTwo-hybridBioGRID16169070 
MAPK9JNK-55 | JNK2 | JNK2A | JNK2ALPHA | JNK2B | JNK2BETA | PRKM9 | SAPK | p54a | p54aSAPKmitogen-activated protein kinase 9Two-hybridBioGRID16169070 
PTP4A3PRL-3 | PRL-R | PRL3protein tyrosine phosphatase type IVA, member 3Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
HOLLMANN_APOPTOSIS_VIA_CD40_UP 201125All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN 805505All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_UP 3823All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
JAIN_NFKB_SIGNALING 7544All SZGR genes in this pathway
ABE_VEGFA_TARGETS_2HR 3421All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_MATURE_CELL 293160All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
YAMASHITA_LIVER_CANCER_WITH_EPCAM_UP 5325All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BAKKER_FOXO3_TARGETS_UP 6141All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-331104110m8hsa-miR-331brainGCCCCUGGGCCUAUCCUAGAA
miR-3813183251A,m8hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-493-5p329335m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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