Gene Page: MLC1

Summary
GeneID  23209
Symbol  MLC1
Synonyms  KIAA0027|LVM|MLC|VL
Description  megalencephalic leukoencephalopathy with subcortical cysts 1
See related  HGNC:17082|MIM:605908|Ensembl:ENSG00000100427|HPRD:05800|
Locus tag  RP3-355C18.4
Gene type  protein-coding
Map location  22q13.33
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003674molecular_functionND11254442 
GO:0003735structural constituent of ribosomeIEA-
GO:0005216ion channel activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006412translationIEA-
GO:0008150biological_processND11254442 
GO:0006811ion transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000299integral to membrane of membrane fractionTAS11254442 
GO:0005840ribosomeIEA-
GO:0005622intracellularIEA-
GO:0005634nucleusIDA18029348 
GO:0005737cytoplasmIDA18029348 
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MYLKDKFZp686I10125 | FLJ12216 | KRP | MLCK | MLCK1 | MLCK108 | MLCK210 | MSTP083 | MYLK1 | smMLCKmyosin light chain kinaseBiochemical ActivityBioGRID10092231 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN 329219All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
CAFFAREL_RESPONSE_TO_THC_24HR_5_DN 5935All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_22Q13_AMPLICON 1715All SZGR genes in this pathway
SHIPP_DLBCL_CURED_VS_FATAL_UP 3922All SZGR genes in this pathway
TAVOR_CEBPA_TARGETS_UP 4836All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_DN 314188All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
MIKKELSEN_MCV6_LCP_WITH_H3K27ME3 2911All SZGR genes in this pathway
MIKKELSEN_NPC_LCP_WITH_H3K4ME3 5834All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_CLASSICAL 162122All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.