Gene Page: GRIP1

Summary
GeneID  23426
Symbol  GRIP1
Synonyms  GRIP
Description  glutamate receptor interacting protein 1
See related  HGNC:18708|MIM:604597|Ensembl:ENSG00000155974|
Locus tag  -
Gene type  protein-coding
Map location  12q14.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ATAD10.930.93
AZIN10.930.94
CNOT70.920.93
AASDHPPT0.920.92
RAB2A0.920.91
PPP1CB0.920.93
CMPK10.920.91
ARCN10.910.91
USP330.910.92
CLASP20.910.91
Top 10 negatively co-expressed genes
MT-CO2-0.70-0.70
FXYD1-0.69-0.70
AF347015.8-0.67-0.68
AF347015.33-0.67-0.67
AF347015.21-0.66-0.63
AF347015.31-0.66-0.67
AF347015.2-0.66-0.67
HIGD1B-0.66-0.66
EIF4EBP3-0.66-0.69
MT-CYB-0.65-0.66
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0003713transcription coactivator activityNAS15572661 
GO:0005515protein bindingIEA-
GO:0005515protein bindingNAS10197531 
GO:0030159receptor signaling complex scaffold activityNAS10197531 
GO:0050681androgen receptor bindingNAS15572661 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007242intracellular signaling cascadeNAS10197531 
GO:0030521androgen receptor signaling pathwayNAS15572661 
GO:0045893positive regulation of transcription, DNA-dependentNAS15572661 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0005783endoplasmic reticulumIEA-
GO:0005886plasma membraneIEA-
GO:0030054cell junctionIEA-
GO:0031410cytoplasmic vesicleIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARAIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFMandrogen receptorTwo-hybridBioGRID10607837 
GRIA1GLUH1 | GLUR1 | GLURA | HBGR1 | MGC133252glutamate receptor, ionotropic, AMPA 1Reconstituted ComplexBioGRID11891216 
GRIA2GLUR2 | GLURB | GluR-K2 | HBGR2glutamate receptor, ionotropic, AMPA 2Reconstituted Complex
Two-hybrid		BioGRID11891216 
GRIA3GLUR-C | GLUR-K3 | GLUR3 | GLURC | MRX94glutamate receptor, ionotrophic, AMPA 3Reconstituted Complex
Two-hybrid		BioGRID11891216 
GRIA4GLUR4 | GLUR4C | GLURDglutamate receptor, ionotrophic, AMPA 4Reconstituted Complex
Two-hybrid		BioGRID11891216 
GRIK1EAA3 | EEA3 | GLR5 | GLUR5glutamate receptor, ionotropic, kainate 1Reconstituted ComplexBioGRID12597860 
GRIK2EAA4 | GLR6 | GLUK6 | GLUR6 | MGC74427 | MRT6glutamate receptor, ionotropic, kainate 2Reconstituted ComplexBioGRID11891216 |12597860 
GRIK3EAA5 | GLR7 | GLUR7 | GluR7aglutamate receptor, ionotropic, kainate 3Reconstituted Complex
Two-hybrid		BioGRID11891216 
GRM3GLUR3 | GPRC1C | MGLUR3 | mGlu3glutamate receptor, metabotropic 3Reconstituted Complex
Two-hybrid		BioGRID11891216 
GRM7FLJ40498 | GLUR7 | GPRC1G | MGLUR7 | mGlu7glutamate receptor, metabotropic 7GRIP interacts with mGluR7b. This interaction was modeled on a demonstrated interaction between GRIP from an unspecified species and human mGluR7b.BIND11891216 
NR2F1COUP-TFI | EAR-3 | EAR3 | ERBAL3 | NR2F2 | SVP44 | TCFCOUP1 | TFCOUP1nuclear receptor subfamily 2, group F, member 1Two-hybridBioGRID10652338 
PRLHRGPR10 | GR3 | MGC126539 | MGC126541 | PrRPRprolactin releasing hormone receptorAffinity Capture-WesternBioGRID11641419 
TESDKFZp586B2022 | MGC1146 | TESS | TESS-2testis derived transcript (3 LIM domains)TES interacts with GRIP1. This interaction was modelled on a demonstrated interaction between human TES and mouse GRIP1.BIND12571287 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BIOCARTA_CARM_ER_PATHWAY 3527All SZGR genes in this pathway
BIOCARTA_HER2_PATHWAY 2217All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_DN 185115All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_DN 165107All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_DN 180110All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_DN 181107All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP 227137All SZGR genes in this pathway
TOMLINS_METASTASIS_DN 2016All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_UP 428266All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_UP 210124All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN 264159All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 435318All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_A 182108All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway


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