Gene Page: GABRA2

Summary
GeneID  2555
Symbol  GABRA2
Synonyms  FLJ97076
Description  gamma-aminobutyric acid (GABA) A receptor, alpha 2
See related  HGNC:4076|MIM:137140|Ensembl:ENSG00000151834|HPRD:11747|
Locus tag  -
Gene type  protein-coding
Map location  4p12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 7 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NRXN30.830.93
OXCT10.830.88
PARK20.820.87
PRMT80.820.85
NPTN0.810.84
MAPK130.810.83
ATP6AP20.810.84
RASGEF1A0.800.85
DRP20.800.87
ZADH20.800.84
Top 10 negatively co-expressed genes
AF347015.21-0.40-0.24
AF347015.18-0.39-0.26
AF347015.2-0.35-0.21
RPL38-0.34-0.40
ANP32C-0.34-0.34
EMX2-0.34-0.42
FAM159B-0.33-0.47
MT-CO2-0.33-0.24
AL139819.3-0.33-0.29
AF347015.26-0.33-0.18
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004890GABA-A receptor activityIEAGABA (GO term level: 7)-
GO:0008503benzodiazepine receptor activityIMPGABA, Neurotransmitter (GO term level: 6)8391122 
GO:0005254chloride channel activityIEA-
GO:0005216ion channel activityIEA-
GO:0005230extracellular ligand-gated ion channel activityIEA-
GO:0031404chloride ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007214gamma-aminobutyric acid signaling pathwayIMPGABA, Neurotransmitter (GO term level: 8)8391122 
GO:0006836neurotransmitter transportIMPneuron, Neurotransmitter (GO term level: 5)8391122 
GO:0001505regulation of neurotransmitter levelsIMPSynap, Neurotransmitter (GO term level: 7)8391122 
GO:0006821chloride transportIEA-
GO:0006811ion transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0030285integral to synaptic vesicle membraneIDASynap (GO term level: 14)8391122 
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0005886plasma membraneIEA-
GO:0030054cell junctionIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
BIOCARTA_GABA_PATHWAY 1010All SZGR genes in this pathway
REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 186155All SZGR genes in this pathway
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL 137110All SZGR genes in this pathway
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 413270All SZGR genes in this pathway
REACTOME_GABA_A_RECEPTOR_ACTIVATION 1212All SZGR genes in this pathway
REACTOME_GABA_RECEPTOR_ACTIVATION 5240All SZGR genes in this pathway
REACTOME_ION_CHANNEL_TRANSPORT 5542All SZGR genes in this pathway
REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT 2121All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP 390236All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
LEE_CALORIE_RESTRICTION_NEOCORTEX_UP 8366All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_24HR_DN 3321All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN 161105All SZGR genes in this pathway
WANG_SMARCE1_TARGETS_UP 280183All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN 264159All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_UP 9362All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN 448282All SZGR genes in this pathway
PHONG_TNF_RESPONSE_VIA_P38_COMPLETE 227151All SZGR genes in this pathway
PHONG_TNF_RESPONSE_VIA_P38_PARTIAL 160106All SZGR genes in this pathway


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