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GeneID |
2561
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Symbol |
GABRB2
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Synonyms |
MGC119386|MGC119388|MGC119389
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Description |
gamma-aminobutyric acid (GABA) A receptor, beta 2 |
See related |
HGNC:4082|MIM:600232|Ensembl:ENSG00000145864|HPRD:02578| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
5q34 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Association | A combined odds ratio method (Sun et al. 2008), association studies | 2 | Link to SZGene | GSMA_I | genome scan meta-analysis | Psr: 0.0032 | | GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.00459 | | GSMA_IIE | genome scan meta-analysis (European-ancestry samples) | Psr: 0.01718 | | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenia, schizophrenias] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 5 | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 31 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
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Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
Top 10 negatively co-expressed genes | |
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0030594 | neurotransmitter receptor activity | IEA | Neurotransmitter (GO term level: 5) | - |
GO:0004890 | GABA-A receptor activity | TAS | GABA (GO term level: 7) | 8264558 |
GO:0005254 | chloride channel activity | IEA | | - |
GO:0005216 | ion channel activity | IEA | | - |
GO:0005230 | extracellular ligand-gated ion channel activity | IEA | | - |
GO:0031404 | chloride ion binding | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0007268 | synaptic transmission | TAS | neuron, Synap, Neurotransmitter (GO term level: 6) | 8264558 |
GO:0007214 | gamma-aminobutyric acid signaling pathway | TAS | GABA, Neurotransmitter (GO term level: 8) | 8264558 |
GO:0006811 | ion transport | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
GO:0045202 | synapse | IEA | neuron, Synap, Neurotransmitter, Glial (GO term level: 2) | - |
GO:0005886 | plasma membrane | IEA | | - |
GO:0005887 | integral to plasma membrane | TAS | | 8264558 |
GO:0030054 | cell junction | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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