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GeneID |
2566
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Symbol |
GABRG2
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Synonyms |
CAE2|ECA2|GEFSP3
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Description |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
See related |
HGNC:4087|MIM:137164|Ensembl:ENSG00000113327|HPRD:00663| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
5q31.1-q33.1 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Association | A combined odds ratio method (Sun et al. 2008), association studies | 2 | Link to SZGene | GSMA_I | genome scan meta-analysis | Psr: 0.0032 | | GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.00459 | | GSMA_IIE | genome scan meta-analysis (European-ancestry samples) | Psr: 0.01718 | | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 6 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
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Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
AP4M1 | 0.92 | 0.92 | | |
SIRT6 | 0.91 | 0.91 | | |
ACTL6B | 0.90 | 0.91 | | |
KAT5 | 0.90 | 0.91 | | |
ZMYND19 | 0.90 | 0.88 | | |
MED22 | 0.90 | 0.90 | | |
STK19 | 0.90 | 0.89 | | |
ACD | 0.90 | 0.91 | | |
MIIP | 0.90 | 0.89 | | |
TRMT1 | 0.89 | 0.91 | | |
Top 10 negatively co-expressed genes | AF347015.31 | -0.75 | -0.79 | | |
AF347015.27 | -0.75 | -0.80 | | |
MT-CO2 | -0.75 | -0.78 | | |
MT-CYB | -0.75 | -0.80 | | |
AF347015.8 | -0.74 | -0.80 | | |
AF347015.33 | -0.73 | -0.77 | | |
AF347015.15 | -0.72 | -0.79 | | |
AF347015.2 | -0.71 | -0.77 | | |
AF347015.26 | -0.68 | -0.77 | | |
AF347015.21 | -0.67 | -0.80 | | |
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Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0030594 | neurotransmitter receptor activity | IEA | Neurotransmitter (GO term level: 5) | - |
GO:0004890 | GABA-A receptor activity | IEA | GABA (GO term level: 7) | - |
GO:0008503 | benzodiazepine receptor activity | TAS | GABA, Neurotransmitter (GO term level: 6) | 2538761 |
GO:0005515 | protein binding | IPI | | 9892355 |
GO:0005254 | chloride channel activity | IEA | | - |
GO:0005216 | ion channel activity | IEA | | - |
GO:0005230 | extracellular ligand-gated ion channel activity | IEA | | - |
GO:0031404 | chloride ion binding | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0007214 | gamma-aminobutyric acid signaling pathway | IEA | GABA, Neurotransmitter (GO term level: 8) | - |
GO:0007214 | gamma-aminobutyric acid signaling pathway | TAS | GABA, Neurotransmitter (GO term level: 8) | 2538761 |
GO:0006821 | chloride transport | IEA | | - |
GO:0006811 | ion transport | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
GO:0045202 | synapse | IEA | neuron, Synap, Neurotransmitter, Glial (GO term level: 2) | - |
GO:0016021 | integral to membrane | IEA | | - |
GO:0005886 | plasma membrane | IEA | | - |
GO:0005887 | integral to plasma membrane | TAS | | 2538761 |
GO:0030054 | cell junction | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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