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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: RNF11

Summary

GeneID

26994

Symbol

RNF11

Synonyms

CGI-123|MGC51169|SID1669

Description

ring finger protein 11

Locus tag

Gene type

protein-coding

Map location

1pter-p22.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0972

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

TAF7

0.94

0.93

COPS3

0.94

GTF2B

0.94

0.93

PSMD14

0.94

0.92

CCT4

0.94

0.95

MRPL44

0.93

ARF4

0.93

0.92

CCT2

0.93

0.94

CCT8

0.92

0.91

MRPL3

0.92

Top 10 negatively co-expressed genes

AF347015.33

-0.72

-0.80

MT-CO2

-0.72

-0.77

AF347015.8

-0.71

-0.79

MT-CYB

-0.71

-0.79

AF347015.26

-0.71

-0.82

AF347015.15

-0.71

-0.80

AF347015.2

-0.70

-0.79

AF347015.27

-0.70

-0.77

AF347015.31

-0.68

-0.74

HLA-F

-0.68

-0.75

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003677

DNA binding

TAS

10673045

GO:0005515

protein binding

IDA

14755250

GO:0008270

zinc ion binding

TAS

10673045

GO:0046872

metal ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0042787

protein ubiquitination during ubiquitin-dependent protein catabolic process

IDA

14755250

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000151

ubiquitin ligase complex

IDA

14755250

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
EPS15	AF-1P \| AF1P \| MLLT5	epidermal growth factor receptor pathway substrate 15	Two-hybrid	BioGRID	14755250
EPS15	AF-1P \| AF1P \| MLLT5	epidermal growth factor receptor pathway substrate 15	RNF11 interacts with EPS15.	BIND	14755250
ITCH	AIF4 \| AIP4 \| NAPP1 \| dJ468O1.1	itchy E3 ubiquitin protein ligase homolog (mouse)	RNF11 interacts with AIP4.	BIND	14559117
RPS27A	CEP80 \| HUBCEP80 \| UBA80 \| UBCEP1 \| UBCEP80	ribosomal protein S27a	RNF11 interacts with RPS27A.	BIND	14755250
RPS27A	CEP80 \| HUBCEP80 \| UBA80 \| UBCEP1 \| UBCEP80	ribosomal protein S27a	Two-hybrid	BioGRID	14755250
SMURF2	DKFZp686F0270 \| MGC138150	SMAD specific E3 ubiquitin protein ligase 2	RNF11 interacts with Smurf2.	BIND	14562029
STAMBP	AMSH \| MGC126516 \| MGC126518	STAM binding protein	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	14755250
STAMBP	AMSH \| MGC126516 \| MGC126518	STAM binding protein	RNF11 interacts with AMSH.	BIND	14755250
STAMBPL1	ALMalpha \| AMSH-FP \| AMSH-LP \| FLJ31524 \| KIAA1373 \| bA399O19.2	STAM binding protein-like 1	Two-hybrid	BioGRID	14755250
UBC	HMG20	ubiquitin C	RNF11 interacts with UbC.	BIND	14755250
UBC	HMG20	ubiquitin C	Two-hybrid	BioGRID	14755250
UBE2D1	E2(17)KB1 \| SFT \| UBC4/5 \| UBCH5 \| UBCH5A	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	RNF11 interacts with UbcH5a.	BIND	14562029
UBE2D2	E2(17)KB2 \| PUBC1 \| UBC4 \| UBC4/5 \| UBCH5B	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	RNF11 interacts with UbcH5b.	BIND	14562029
UBE2D3	E2(17)KB3 \| MGC43926 \| MGC5416 \| UBC4/5 \| UBCH5C	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	RNF11 interacts with UbcH5c.	BIND	14562029
ZNF350	ZBRK1 \| ZFQR	zinc finger protein 350	RNF11 interacts with ZBRK1.	BIND	14755250
ZNF350	ZBRK1 \| ZFQR	zinc finger protein 350	Two-hybrid	BioGRID	14755250

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN	136	86	All SZGR genes in this pathway
NAM_FXYD5_TARGETS_DN	18	11	All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP	332	228	All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP	177	110	All SZGR genes in this pathway
HORIUCHI_WTAP_TARGETS_DN	310	188	All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN	800	473	All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL	326	213	All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN	712	443	All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN	848	527	All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP	176	115	All SZGR genes in this pathway
GOLDRATH_HOMEOSTATIC_PROLIFERATION	171	102	All SZGR genes in this pathway
NEMETH_INFLAMMATORY_RESPONSE_LPS_UP	88	64	All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION	405	264	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN	1237	837	All SZGR genes in this pathway
RUAN_RESPONSE_TO_TNF_TROGLITAZONE_DN	42	24	All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN	830	547	All SZGR genes in this pathway
RUAN_RESPONSE_TO_TNF_DN	84	50	All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN	434	302	All SZGR genes in this pathway
BURTON_ADIPOGENESIS_6	189	112	All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5	482	296	All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED	1022	619	All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G	95	62	All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN	270	181	All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP	439	257	All SZGR genes in this pathway
BASSO_HAIRY_CELL_LEUKEMIA_DN	80	66	All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_DN	210	128	All SZGR genes in this pathway
RAGHAVACHARI_PLATELET_SPECIFIC_GENES	70	46	All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN	207	139	All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP	756	494	All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP	682	440	All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP	548	370	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124.1	526	532	m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	526	532	1A	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	526	532	1A	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-129-5p	465	471	1A	hsa-miR-129^brain	CUUUUUGCGGUCUGGGCUUGC
miR-129-5p	465	471	1A	hsa-miR-129-5p	CUUUUUGCGGUCUGGGCUUGCU
miR-130/301	682	688	1A	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-141/200a	280	286	1A	hsa-miR-141	UAACACUGUCUGGUAAAGAUGG
miR-141/200a	280	286	1A	hsa-miR-200a	UAACACUGUCUGGUAACGAUGU
miR-186	393	399	m8	hsa-miR-186	CAAAGAAUUCUCCUUUUGGGCUU
miR-19	487	494	1A,m8	hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
				hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
				hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
				hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
miR-199	452	458	m8	hsa-miR-199a	CCCAGUGUUCAGACUACCUGUUC
miR-199	452	458	m8	hsa-miR-199b	CCCAGUGUUUAGACUAUCUGUUC
miR-24	62	68	m8	hsa-miR-24^SZ	UGGCUCAGUUCAGCAGGAACAG
miR-362	997	1003	1A	hsa-miR-362	AAUCCUUGGAACCUAGGUGUGAGU
miR-369-3p	549	555	m8	hsa-miR-369-3p	AAUAAUACAUGGUUGAUCUUU
miR-381	1170	1176	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-384	326	332	1A	hsa-miR-384	AUUCCUAGAAAUUGUUCAUA
miR-384	326	332	1A	hsa-miR-384	AUUCCUAGAAAUUGUUCAUA
miR-496	200	206	1A	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-544	639	645	m8	hsa-miR-544	AUUCUGCAUUUUUAGCAAGU
miR-9	68	74	1A	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.