Gene Page: FOXP1

Summary
GeneID  27086
Symbol  FOXP1
Synonyms  12CC4|FLJ23741|HSPC215|MGC12942|MGC88572|MGC99551|QRF1|hFKH1B
Description  forkhead box P1
See related  HGNC:3823|MIM:605515|Ensembl:ENSG00000114861|HPRD:18518|
Locus tag  -
Gene type  protein-coding
Map location  3p14.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.04047 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04359 
ExpressionExpressionP value: 1.87 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MRTO40.790.79
NARFL0.780.78
CDK100.780.79
NCAPH20.770.80
RAB240.770.77
PICK10.770.76
TTLL30.770.77
STK250.760.76
RING10.760.77
PNKP0.760.75
Top 10 negatively co-expressed genes
AF347015.2-0.64-0.59
AF347015.8-0.63-0.58
AF347015.15-0.62-0.59
AF347015.31-0.62-0.58
MT-CYB-0.62-0.59
AF347015.27-0.61-0.59
MT-ATP8-0.61-0.63
AF347015.26-0.60-0.59
MT-CO2-0.60-0.54
AF347015.33-0.59-0.56
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0003705RNA polymerase II transcription factor activity, enhancer bindingIEA-
GO:0008270zinc ion bindingIEA-
GO:0016566specific transcriptional repressor activityIEA-
GO:0042803protein homodimerization activityIEA-
GO:0046872metal ion bindingIEA-
GO:0046982protein heterodimerization activityIEA-
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007519skeletal muscle developmentIEAneuron (GO term level: 8)-
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA-
GO:0002639positive regulation of immunoglobulin productionIEA-
GO:0002053positive regulation of mesenchymal cell proliferationIEA-
GO:0002329pre-B cell differentiationIEA-
GO:0055007cardiac muscle cell differentiationIEA-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0009790embryonic developmentIEA-
GO:0007507heart developmentIEA-
GO:0016481negative regulation of transcriptionIEA-
GO:0033152immunoglobulin V(D)J recombinationIEA-
GO:0030324lung developmentIEA-
GO:0048745smooth muscle developmentIEA-
GO:0050679positive regulation of epithelial cell proliferationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005634nucleusIEA-
GO:0005730nucleolusIDA18029348 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CTBP1BARS | MGC104684C-terminal binding protein 1-HPRD,BioGRID14701752 
FOXP112CC4 | FLJ23741 | HSPC215 | MGC12942 | MGC88572 | MGC99551 | QRF1 | hFKH1Bforkhead box P1Affinity Capture-WesternBioGRID14701752 
FOXP2CAGH44 | DKFZp686H1726 | SPCH1 | TNRC10forkhead box P2-HPRD,BioGRID14701752 
FOXP4FLJ40908 | FLJ44184 | hFKHLAforkhead box P4-HPRD,BioGRID14701752 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN 13686All SZGR genes in this pathway
RODRIGUES_DCC_TARGETS_DN 12184All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN 805505All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN 537339All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN 5135All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN 14295All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_UP 11578All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN 770415All SZGR genes in this pathway
MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP 169127All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN 514319All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_DN 411249All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP 195138All SZGR genes in this pathway
MCCLUNG_CREB1_TARGETS_DN 5739All SZGR genes in this pathway
HAN_JNK_SINGALING_UP 3521All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_DN 14294All SZGR genes in this pathway
SAFFORD_T_LYMPHOCYTE_ANERGY 8754All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 482296All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN 3729All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN 409268All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP 673430All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MIKKELSEN_DEDIFFERENTIATED_STATE_DN 77All SZGR genes in this pathway
MARSON_FOXP3_TARGETS_DN 5438All SZGR genes in this pathway
ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN 4630All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 7654All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN 315215All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP 289184All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_UP 489314All SZGR genes in this pathway
ZWANG_EGF_PERSISTENTLY_DN 6136All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1/2067737791Ahsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
hsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
hsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
miR-132/212269727031Ahsa-miR-212SZUAACAGUCUCCAGUCACGGCC
hsa-miR-132brainUAACAGUCUACAGCCAUGGUCG
miR-13928082814m8hsa-miR-139brainUCUACAGUGCACGUGUCU
miR-141/200a282288m8hsa-miR-141UAACACUGUCUGGUAAAGAUGG
hsa-miR-200aUAACACUGUCUGGUAACGAUGU
miR-150172178m8hsa-miR-150UCUCCCAACCCUUGUACCAGUG
miR-181705711m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-183153159m8hsa-miR-183UAUGGCACUGGUAGAAUUCACUG
miR-194394461A,m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-191823829m8hsa-miR-191brainCAACGGAAUCCCAAAAGCAGCU
miR-2225232529m8hsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
miR-221/222281028161Ahsa-miR-221brainAGCUACAUUGUCUGCUGGGUUUC
hsa-miR-222brainAGCUACAUCUGGCUACUGGGUCUC
miR-30-3p288628931A,m8hsa-miR-30a-3pCUUUCAGUCGGAUGUUUGCAGC
hsa-miR-30e-3pCUUUCAGUCGGAUGUUUACAGC
miR-324-3p71771Ahsa-miR-324-3pCCACUGCCCCAGGUGCUGCUGG
miR-3295405461Ahsa-miR-329brainAACACACCUGGUUAACCUCUUU
miR-33135613621Ahsa-miR-33GUGCAUUGUAGUUGCAUUG
hsa-miR-33bGUGCAUUGCUGUUGCAUUGCA
miR-34/449465471m8hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
miR-34b466472m8hsa-miR-34bUAGGCAGUGUCAUUAGCUGAUUG
hsa-miR-34bUAGGCAGUGUCAUUAGCUGAUUG
miR-369-3p7257311Ahsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-374725731m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-409-3p819825m8hsa-miR-409-3pCGAAUGUUGCUCGGUGAACCCCU
miR-5437067131A,m8hsa-miR-543AAACAUUCGCGGUGCACUUCU
miR-9173017371A,m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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