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GeneID |
2741
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Symbol |
GLRA1
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Synonyms |
MGC138878|MGC138879|STHE
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Description |
glycine receptor, alpha 1 |
See related |
HGNC:4326|MIM:138491|Ensembl:ENSG00000145888|HPRD:00719| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
5q32 |
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Gene set name |
Method of gene set |
Evidence |
Info |
GSMA_I | genome scan meta-analysis | Psr: 0.0032 | | GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.00459 | | GSMA_IIE | genome scan meta-analysis (European-ancestry samples) | Psr: 0.01718 | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 9 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
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Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
Top 10 negatively co-expressed genes | |
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0030594 | neurotransmitter receptor activity | IEA | Neurotransmitter (GO term level: 5) | - |
GO:0004890 | GABA-A receptor activity | IEA | GABA (GO term level: 7) | - |
GO:0004872 | receptor activity | IEA | | - |
GO:0005515 | protein binding | IPI | | 11929858 |
GO:0005216 | ion channel activity | IEA | | - |
GO:0005230 | extracellular ligand-gated ion channel activity | IEA | | - |
GO:0016934 | extracellular-glycine-gated chloride channel activity | IDA | | 2155780 |8137830 |
GO:0016594 | glycine binding | IDA | | 2155780 |15748848 |
GO:0030977 | taurine binding | IDA | | 15748848 |
GO:0031404 | chloride ion binding | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0051970 | negative regulation of transmission of nerve impulse | IMP | neuron (GO term level: 7) | 11973623 |
GO:0060080 | regulation of inhibitory postsynaptic membrane potential | IEA | neuron, Synap (GO term level: 10) | - |
GO:0007268 | synaptic transmission | IEA | neuron, Synap, Neurotransmitter (GO term level: 6) | - |
GO:0060012 | synaptic transmission, glycinergic | IEA | neuron, Synap, Neurotransmitter (GO term level: 8) | - |
GO:0007218 | neuropeptide signaling pathway | IDA | Neurotransmitter (GO term level: 8) | 2155780 |
GO:0002087 | regulation of respiratory gaseous exchange by neurological process | IEA | Brain (GO term level: 6) | - |
GO:0001508 | regulation of action potential | IEA | | - |
GO:0001964 | startle response | IMP | | 8298642 |11973623 |
GO:0007628 | adult walking behavior | IEA | | - |
GO:0007601 | visual perception | IEA | | - |
GO:0006821 | chloride transport | IDA | | 8137830 |
GO:0006811 | ion transport | IDA | | 2155780 |
GO:0006936 | muscle contraction | IMP | | 11973623 |
GO:0007340 | acrosome reaction | IEA | | - |
GO:0060013 | righting reflex | IEA | | - |
GO:0050884 | neuromuscular process controlling posture | IEA | | - |
GO:0043576 | regulation of respiratory gaseous exchange | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
GO:0045202 | synapse | IEA | neuron, Synap, Neurotransmitter, Glial (GO term level: 2) | - |
GO:0005622 | intracellular | IEA | | - |
GO:0005624 | membrane fraction | IEA | | - |
GO:0009897 | external side of plasma membrane | IEA | | - |
GO:0005886 | plasma membrane | IEA | | - |
GO:0005887 | integral to plasma membrane | IDA | | 7506679 |
GO:0005887 | integral to plasma membrane | IMP | | 11973623 |
GO:0005887 | integral to plasma membrane | NAS | | 2155780 |
GO:0030054 | cell junction | IEA | | - |
GO:0043231 | intracellular membrane-bounded organelle | IDA | | 7506679 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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