Gene Page: ABR

Summary
GeneID  29
Symbol  ABR
Synonyms  FLJ45954|MDB
Description  active BCR-related gene
See related  HGNC:81|MIM:600365|Ensembl:ENSG00000159842|HPRD:02649|
Locus tag  -
Gene type  protein-coding
Map location  17p13.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CPT1A0.850.83
ACSS10.850.83
FYCO10.850.86
TPCN10.840.79
ITPKB0.840.80
CHDH0.830.73
OPLAH0.820.75
FAM38A0.820.77
DOCK10.820.81
ATP1A20.800.76
Top 10 negatively co-expressed genes
VPS29-0.49-0.55
MED19-0.49-0.54
C12orf73-0.49-0.53
TAF9-0.49-0.52
NT5C3L-0.48-0.55
PSMA6-0.47-0.58
POLB-0.47-0.52
STMN1-0.46-0.48
TXNL1-0.46-0.51
DCUN1D5-0.46-0.48
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005089Rho guanyl-nucleotide exchange factor activityIEA-
GO:0005085guanyl-nucleotide exchange factor activityIEA-
GO:0005096GTPase activator activityTAS8262969 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007420brain developmentIEABrain (GO term level: 7)-
GO:0007242intracellular signaling cascadeIEA-
GO:0007264small GTPase mediated signal transductionTAS8262969 
GO:0035023regulation of Rho protein signal transductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_RHOA_REG_PATHWAY 4630All SZGR genes in this pathway
PID_RAC1_REG_PATHWAY 3825All SZGR genes in this pathway
REACTOME_SIGNALING_BY_RHO_GTPASES 11381All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF 217167All SZGR genes in this pathway
REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK 4333All SZGR genes in this pathway
REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE 6043All SZGR genes in this pathway
REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 8161All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_G_ALPHA1213_SIGNALLING_EVENTS 7456All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN 9251All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
HUTTMANN_B_CLL_POOR_SURVIVAL_UP 276187All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_UP 380236All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP 418263All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
MORI_SMALL_PRE_BII_LYMPHOCYTE_DN 7652All SZGR genes in this pathway
ROSS_ACUTE_MYELOID_LEUKEMIA_CBF 8257All SZGR genes in this pathway
SMITH_TERT_TARGETS_DN 8769All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR 544307All SZGR genes in this pathway
RAMALHO_STEMNESS_DN 7455All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP 163102All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
YAGI_AML_WITH_11Q23_REARRANGED 351238All SZGR genes in this pathway
YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_DN 6531All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN 5639All SZGR genes in this pathway
KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN 225124All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1221011071Ahsa-miR-122aUGGAGUGUGACAAUGGUGUUUGU
miR-124.111611167m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/506116111671Ahsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-125/35116371643m8hsa-miR-125bbrainUCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrainUCCCUGAGACCCUUUAACCUGUG
miR-1451331401A,m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-19254725541A,m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-299-5p249825051A,m8hsa-miR-299-5pUGGUUUACCGUCCCACAUACAU
miR-34/449119412011A,m8hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
miR-369-3p248424901Ahsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-37022912297m8hsa-miR-370brainGCCUGCUGGGGUGGAACCUGG
miR-374248424911A,m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-493-5p1641701Ahsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-496249625021Ahsa-miR-496AUUACAUGGCCAAUCUC
miR-543251725231Ahsa-miR-543AAACAUUCGCGGUGCACUUCU
miR-5442842901Ahsa-miR-544AUUCUGCAUUUUUAGCAAGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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