Gene Page: GZMK

Summary
GeneID  3003
Symbol  GZMK
Synonyms  TRYP2
Description  granzyme K (granzyme 3; tryptase II)
See related  HGNC:4711|MIM:600784|Ensembl:ENSG00000113088|HPRD:02872|
Locus tag  -
Gene type  protein-coding
Map location  5q11-q12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RPL220.860.81
RPL70.810.71
METTL30.800.78
AC021224.10.790.79
AC008038.10.750.82
CCNL10.740.67
LASS50.740.70
EXOSC100.740.72
ZNF1330.740.71
TIA10.740.72
Top 10 negatively co-expressed genes
HLA-F-0.57-0.70
FBXO2-0.54-0.66
LDHD-0.54-0.66
AIFM3-0.54-0.64
HLA-E-0.54-0.68
ALDOC-0.54-0.64
HLA-C-0.54-0.66
CLU-0.53-0.63
PTH1R-0.53-0.66
TNFSF12-0.53-0.65
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityIEAglutamate (GO term level: 7)-
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN 320184All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_DN 406230All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_DN 226132All SZGR genes in this pathway
HAHTOLA_SEZARY_SYNDROM_DN 4226All SZGR genes in this pathway
FARMER_BREAST_CANCER_CLUSTER_1 4423All SZGR genes in this pathway
WIELAND_UP_BY_HBV_INFECTION 10166All SZGR genes in this pathway
ROETH_TERT_TARGETS_DN 87All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_8HR_DN 4731All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_UP 487303All SZGR genes in this pathway
ABE_VEGFA_TARGETS_30MIN 2921All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_12HR_DN 10164All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_P7 9052All SZGR genes in this pathway
WALLACE_PROSTATE_CANCER_RACE_UP 299167All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
GOLDRATH_ANTIGEN_RESPONSE 346192All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_UP 288168All SZGR genes in this pathway
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP 7646All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_30MIN_DN 15099All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN 254158All SZGR genes in this pathway
BOSCO_TH1_CYTOTOXIC_MODULE 11462All SZGR genes in this pathway


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