Gene Page: APBA2

Summary
GeneID  321
Symbol  APBA2
Synonyms  D15S1518E|HsT16821|LIN-10|MGC99508|MGC:14091|MINT2|X11L
Description  amyloid beta (A4) precursor protein-binding, family A, member 2
See related  HGNC:579|MIM:602712|Ensembl:ENSG00000034053|HPRD:04090|
Locus tag  -
Gene type  protein-coding
Map location  15q11-q12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
KIF5C0.810.88
DLG20.750.82
AKAP60.750.84
OXCT10.750.72
FAM102B0.740.82
AL133410.30.720.78
SHANK20.720.83
BARX20.710.36
ANKRD60.710.68
KCNT20.710.78
Top 10 negatively co-expressed genes
S100A1-0.44-0.49
NUDT8-0.42-0.50
S100A13-0.40-0.55
FXYD1-0.40-0.52
AC021016.1-0.40-0.51
AF347015.21-0.40-0.50
C1orf54-0.38-0.55
MT-CO2-0.38-0.53
HIGD1B-0.38-0.54
AF347015.2-0.38-0.47
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
GO:0005515protein bindingIPI10833507 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)9890987 
GO:0015031protein transportIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APPAAA | ABETA | ABPP | AD1 | APPI | CTFgamma | CVAP | PN2amyloid beta (A4) precursor protein-HPRD,BioGRID9890987 
CLSTN1ALC-ALPHA | CSTN1 | FLJ32258 | KIAA0911 | PIK3CD | XB31alpha | alcalpha1 | alcalpha2calsyntenin 1-HPRD,BioGRID12972431 
CLSTN3CSTN3 | KIAA0726 | MGC131797 | MGC138488 | alcbetacalsyntenin 3-HPRD12972431 
LRP1A2MR | APOER | APR | CD91 | FLJ16451 | IGFBP3R | LRP | MGC88725 | TGFBR5low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)Two-hybridBioGRID10827173 
LRP2DBS | gp330low density lipoprotein-related protein 2Two-hybridBioGRID10827173 
LRP8APOER2 | HSZ75190 | MCI1low density lipoprotein receptor-related protein 8, apolipoprotein e receptorTwo-hybridBioGRID10827173 
NECAB3APBA2BP | EFCBP3 | NIP1 | STIP3 | SYTIP2 | XB51 | dJ63M2.4 | dJ63M2.5N-terminal EF-hand calcium binding protein 3-HPRD,BioGRID10833507 
NRXN1DKFZp313P2036 | FLJ35941 | Hs.22998 | KIAA0578neurexin 1-HPRD,BioGRID11036064 
PSEN2AD3L | AD4 | PS2 | STM2presenilin 2 (Alzheimer disease 4)Affinity Capture-WesternBioGRID12196555 
RELAMGC131774 | NFKB3 | p65v-rel reticuloendotheliosis viral oncogene homolog A (avian)-HPRD,BioGRID10777610 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
HAHTOLA_SEZARY_SYNDROM_DN 4226All SZGR genes in this pathway
AMUNDSON_RESPONSE_TO_ARSENITE 217143All SZGR genes in this pathway
YANG_BREAST_CANCER_ESR1_BULK_DN 2315All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
RICKMAN_METASTASIS_UP 344180All SZGR genes in this pathway
KANNAN_TP53_TARGETS_DN 2115All SZGR genes in this pathway
MA_MYELOID_DIFFERENTIATION_DN 4430All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
MCCLUNG_DELTA_FOSB_TARGETS_2WK 4836All SZGR genes in this pathway
LOPES_METHYLATED_IN_COLON_CANCER_UP 2720All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN 315197All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
ZHANG_TLX_TARGETS_UP 10878All SZGR genes in this pathway
ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN 4630All SZGR genes in this pathway
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN 7447All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
NIELSEN_SYNOVIAL_SARCOMA_UP 1814All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_30MIN_UP 5638All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-128104410511A,m8hsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-224104810551A,m8hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-2710451051m8hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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