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| GeneID |
3351
|
| Symbol |
HTR1B
|
| Synonyms |
5-HT1B|5-HT1DB|HTR1D2|HTR1DB|S12
|
| Description |
5-hydroxytryptamine (serotonin) receptor 1B |
| See related |
HGNC:5287|MIM:182131|Ensembl:ENSG00000135312|HPRD:01634| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
6q13 |
|
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| Gene set name |
Method of gene set |
Evidence |
Info |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 2 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| CNGA3 | 0.85 | 0.67 | | |
| IQGAP2 | 0.82 | 0.77 | | |
| EEPD1 | 0.79 | 0.66 | | |
| MRC2 | 0.79 | 0.72 | | |
| CMTM3 | 0.79 | 0.73 | | |
| ERBB2 | 0.78 | 0.68 | | |
| SNCAIP | 0.77 | 0.73 | | |
| LOXL1 | 0.77 | 0.72 | | |
| PALLD | 0.77 | 0.61 | | |
| SEMA5B | 0.77 | 0.60 | | |
Top 10 negatively co-expressed genes | | HLA-F | -0.37 | -0.42 | | |
| C5orf53 | -0.37 | -0.46 | | |
| CA4 | -0.36 | -0.47 | | |
| FBXO2 | -0.36 | -0.39 | | |
| PTGDS | -0.36 | -0.44 | | |
| AF347015.27 | -0.36 | -0.49 | | |
| CA11 | -0.35 | -0.50 | | |
| AF347015.33 | -0.35 | -0.47 | | |
| MT-CO2 | -0.34 | -0.48 | | |
| AF347015.31 | -0.34 | -0.47 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004993 | serotonin receptor activity | TAS | serotonin, Neurotransmitter (GO term level: 8) | 1315531 |
| GO:0004872 | receptor activity | IEA | | - |
| GO:0005515 | protein binding | IPI | | 17353931 |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007268 | synaptic transmission | TAS | neuron, Synap, Neurotransmitter (GO term level: 6) | 1351684 |
| GO:0007187 | G-protein signaling, coupled to cyclic nucleotide second messenger | TAS | | 1559993 |
| GO:0007165 | signal transduction | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005886 | plasma membrane | IEA | | - |
| GO:0005887 | integral to plasma membrane | TAS | | 1559993 |
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