Gene Page: IK

Summary
GeneID  3550
Symbol  IK
Synonyms  CSA2|MGC59741|RED
Description  IK cytokine, down-regulator of HLA II
See related  HGNC:5958|MIM:600549|HPRD:02771|
Locus tag  -
Gene type  protein-coding
Map location  2p15-p14|5q31.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0032 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PCSK10.640.43
SNAP250.610.47
LRRK20.610.46
MKX0.600.40
FGFR1OP20.600.47
ZNF3650.580.40
HTR1F0.580.42
GABRA10.580.43
AC110760.20.580.41
NIPAL20.580.44
Top 10 negatively co-expressed genes
BCL7C-0.33-0.36
WDR86-0.30-0.30
TBC1D10A-0.29-0.23
AL110504.3-0.29-0.25
PKN1-0.29-0.29
EMID1-0.29-0.30
SH2B2-0.28-0.33
CENPB-0.28-0.26
FADS2-0.28-0.20
C1orf86-0.28-0.27
Gene Ontology
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007267cell-cell signalingTAS7970704 
GO:0006955immune responseTAS7970704 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005615extracellular spaceTAS7970704 
GO:0005625soluble fractionTAS7970704 
GO:0005634nucleusIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CHD3Mi-2a | Mi2-ALPHA | ZFHchromodomain helicase DNA binding protein 3Two-hybridBioGRID16169070 
FANCCFA3 | FAC | FACC | FLJ14675Fanconi anemia, complementation group CTwo-hybridBioGRID14499622 
KAT5ESA1 | HTATIP | HTATIP1 | PLIP | TIP | TIP60 | cPLA2K(lysine) acetyltransferase 5Two-hybridBioGRID16169070 
NUP62DKFZp547L134 | FLJ20822 | FLJ43869 | IBSN | MGC841 | SNDI | p62nucleoporin 62kDaTwo-hybridBioGRID16169070 
PFN2D3S1319E | PFLprofilin 2Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN 320184All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
SHIPP_DLBCL_CURED_VS_FATAL_DN 4530All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 151100All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 5135All SZGR genes in this pathway
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN 7345All SZGR genes in this pathway
ASTIER_INTEGRIN_SIGNALING 5944All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN 172107All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 473224All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_T7 9863All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_UP 425253All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.