Gene Page: AQP1

Summary
GeneID  358
Symbol  AQP1
Synonyms  AQP-CHIP|CHIP28|CO|MGC26324
Description  aquaporin 1 (Colton blood group)
See related  HGNC:633|MIM:107776|Ensembl:ENSG00000106125|HPRD:00140|
Locus tag  -
Gene type  protein-coding
Map location  7p14
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.625 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PLSCR40.910.90
SSPN0.880.87
ADD30.870.84
PDLIM50.870.76
EDNRB0.840.89
SLC15A20.840.87
GJA10.840.85
PPAP2B0.840.80
GLUD10.840.86
BMPR1B0.830.77
Top 10 negatively co-expressed genes
BZW2-0.41-0.63
MPP3-0.41-0.58
KIAA1949-0.41-0.48
MYCN-0.40-0.54
ZNF124-0.40-0.61
ZNF821-0.40-0.59
NFIL3-0.40-0.57
ISLR2-0.40-0.56
DPF1-0.40-0.56
ZNF48-0.39-0.57
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005372water transporter activityTAS7521540 
GO:0005215transporter activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007588excretionTAS1722319 
GO:0006833water transportTAS7521540 
GO:0006810transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0005887integral to plasma membraneTAS1722319 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AQP1AQP-CHIP | CHIP28 | CO | MGC26324aquaporin 1 (Colton blood group)-HPRD10872456 
CCDC85BDIPAcoiled-coil domain containing 85BTwo-hybridBioGRID16189514 
EFEMP2FBLN4 | MBP1 | UPH1EGF-containing fibulin-like extracellular matrix protein 2Two-hybridBioGRID16189514 
KCTD17FLJ12242 | FLJ98761potassium channel tetramerisation domain containing 17Two-hybridBioGRID16189514 
KRTAP4-12KAP4.12 | KRTAP4.12keratin associated protein 4-12Two-hybridBioGRID16189514 
MDFII-MF | I-mfaMyoD family inhibitorTwo-hybridBioGRID16189514 
TRIP6MGC10556 | MGC10558 | MGC29959 | MGC3837 | MGC4423 | OIP1 | ZRP-1thyroid hormone receptor interactor 6Two-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION 2316All SZGR genes in this pathway
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 413270All SZGR genes in this pathway
REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS 117All SZGR genes in this pathway
REACTOME_AQUAPORIN_MEDIATED_TRANSPORT 5134All SZGR genes in this pathway
REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS 4430All SZGR genes in this pathway
BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN 169118All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN 4129All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP 204140All SZGR genes in this pathway
SENESE_HDAC1_AND_HDAC2_TARGETS_DN 232139All SZGR genes in this pathway
SENESE_HDAC2_TARGETS_DN 13377All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_UP 162116All SZGR genes in this pathway
BIDUS_METASTASIS_DN 16193All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN 14295All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN 153100All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_UP 11578All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP 211136All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_UP 1913All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B 392251All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
CERVERA_SDHB_TARGETS_1_UP 11866All SZGR genes in this pathway
SHEPARD_BMYB_MORPHOLINO_DN 200112All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP 7958All SZGR genes in this pathway
HOEGERKORP_CD44_TARGETS_DIRECT_UP 2721All SZGR genes in this pathway
JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN 6445All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_UP 8648All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
BURTON_ADIPOGENESIS_3 10164All SZGR genes in this pathway
BURTON_ADIPOGENESIS_PEAK_AT_24HR 4330All SZGR genes in this pathway
LIANG_SILENCED_BY_METHYLATION_UP 3218All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP 673430All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
BOQUEST_STEM_CELL_DN 216143All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_DN 222141All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_DN 253192All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
BILANGES_SERUM_SENSITIVE_GENES 9054All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
VANLOO_SP3_TARGETS_DN 8947All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_DN 244157All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway


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