Gene Page: KCNJ8

Summary
GeneID  3764
Symbol  KCNJ8
Synonyms  KIR6.1|uKATP-1
Description  potassium inwardly-rectifying channel, subfamily J, member 8
See related  HGNC:6269|MIM:600935|Ensembl:ENSG00000121361|HPRD:02962|
Locus tag  -
Gene type  protein-coding
Map location  12p11.23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.517 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005244voltage-gated ion channel activityIEA-
GO:0015272ATP-activated inward rectifier potassium channel activityIEA-
GO:0030955potassium ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007507heart developmentIEA-
GO:0006811ion transportIEA-
GO:0006813potassium ion transportTAS7890693 
GO:0051607defense response to virusIEA-
GO:0032496response to lipopolysaccharideIEA-
GO:0043330response to exogenous dsRNAIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0030016myofibrilIEA-
GO:0008076voltage-gated potassium channel complexTAS7890693 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ABCC8ABC36 | HHF1 | HI | HRINS | MRP8 | PHHI | SUR | SUR1 | TNDM2ATP-binding cassette, sub-family C (CFTR/MRP), member 8-HPRD11160857 
ABCC9ABC37 | CMD1O | FLJ36852 | SUR2ATP-binding cassette, sub-family C (CFTR/MRP), member 9-HPRD11007308 
KCNJ11BIR | HHF2 | IKATP | KIR6.2 | MGC133230 | PHHI | TNDM3potassium inwardly-rectifying channel, subfamily J, member 11Affinity Capture-WesternBioGRID11136227 
KCNJ2HHBIRK1 | HHIRK1 | IRK1 | KIR2.1 | LQT7 | SQT3potassium inwardly-rectifying channel, subfamily J, member 2-HPRD10559219 
KCNJ8KIR6.1 | uKATP-1potassium inwardly-rectifying channel, subfamily J, member 8-HPRD10559219 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
REACTOME_POTASSIUM_CHANNELS 9868All SZGR genes in this pathway
REACTOME_INWARDLY_RECTIFYING_K_CHANNELS 3120All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
THUM_SYSTOLIC_HEART_FAILURE_DN 244147All SZGR genes in this pathway
ROY_WOUND_BLOOD_VESSEL_UP 5030All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
ROVERSI_GLIOMA_LOH_REGIONS 4430All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_5 14789All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 153102All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP 769437All SZGR genes in this pathway
IIZUKA_LIVER_CANCER_PROGRESSION_G1_G2_UP 129All SZGR genes in this pathway
MATSUDA_NATURAL_KILLER_DIFFERENTIATION 475313All SZGR genes in this pathway
CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN 4232All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP 176110All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN 17997All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S3 266180All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


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