Gene Page: KCNJ9

Summary
GeneID  3765
Symbol  KCNJ9
Synonyms  GIRK3|KIR3.3
Description  potassium inwardly-rectifying channel, subfamily J, member 9
See related  HGNC:6270|MIM:600932|Ensembl:ENSG00000162728|HPRD:02959|
Locus tag  RP11-536C5.1
Gene type  protein-coding
Map location  1q21-q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.6703 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MICAL20.870.79
SNAP250.860.78
KCNK10.860.86
EXTL10.850.87
PIP5K1B0.850.86
CAMK2A0.850.85
VSNL10.850.75
KCNAB20.850.79
SYT120.840.87
VIPR10.840.85
Top 10 negatively co-expressed genes
KIAA1949-0.59-0.55
SH3BP2-0.58-0.67
TUBB2B-0.58-0.63
BCL7C-0.57-0.70
SH2B2-0.56-0.65
PKN1-0.56-0.56
TRAF4-0.56-0.65
PDE9A-0.55-0.61
C21orf30-0.54-0.54
FNBP1L-0.54-0.42
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005244voltage-gated ion channel activityIEA-
GO:0015467G-protein activated inward rectifier potassium channel activityIEA-
GO:0030955potassium ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006811ion transportIEA-
GO:0006813potassium ion transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ADRB2ADRB2R | ADRBR | B2AR | BAR | BETA2ARadrenergic, beta-2-, receptor, surface-HPRD12297500 
DRD2D2DR | D2Rdopamine receptor D2-HPRD12297500 
DRD4D4DRdopamine receptor D4-HPRD,BioGRID12297500 
KCNJ3GIRK1 | KGA | KIR3.1potassium inwardly-rectifying channel, subfamily J, member 3-HPRD12297500 
KCNJ6BIR1 | GIRK2 | KATP2 | KCNJ7 | KIR3.2 | MGC126596 | hiGIRK2potassium inwardly-rectifying channel, subfamily J, member 6-HPRD,BioGRID10956667 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ST_G_ALPHA_I_PATHWAY 3529All SZGR genes in this pathway
ST_ADRENERGIC 3629All SZGR genes in this pathway
ST_MYOCYTE_AD_PATHWAY 2725All SZGR genes in this pathway
REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 186155All SZGR genes in this pathway
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL 137110All SZGR genes in this pathway
REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS 2517All SZGR genes in this pathway
REACTOME_GABA_B_RECEPTOR_ACTIVATION 3826All SZGR genes in this pathway
REACTOME_GABA_RECEPTOR_ACTIVATION 5240All SZGR genes in this pathway
REACTOME_POTASSIUM_CHANNELS 9868All SZGR genes in this pathway
REACTOME_INWARDLY_RECTIFYING_K_CHANNELS 3120All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
CHESLER_BRAIN_QTL_CIS 7551All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_CIS 6538All SZGR genes in this pathway
CHESLER_BRAIN_HIGHEST_GENETIC_VARIANCE 3721All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
MIKKELSEN_MEF_ICP_WITH_H3K27ME3 206108All SZGR genes in this pathway
MIKKELSEN_IPS_ICP_WITH_H3K27ME3 5432All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K27ME3 4227All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_12 7954All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


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