Gene Page: KCNN2

Summary
GeneID  3781
Symbol  KCNN2
Synonyms  KCa2.2|SK2|SKCA2|hSK2
Description  potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
See related  HGNC:6291|MIM:605879|Ensembl:ENSG00000080709|HPRD:09323|
Locus tag  -
Gene type  protein-coding
Map location  5q22.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005516calmodulin bindingIEA-
GO:0005216ion channel activityIEA-
GO:0016286small conductance calcium-activated potassium channel activityTAS10991935 
GO:0015269calcium-activated potassium channel activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006811ion transportIEA-
GO:0006813potassium ion transportIEA-
GO:0006813potassium ion transportNAS10991935 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0016021integral to membraneNAS10991935 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CALM1CALML2 | CAMI | DD132 | PHKDcalmodulin 1 (phosphorylase kinase, delta)-HPRD,BioGRID11323678 
KCNN2KCa2.2 | SK2 | SKCA2 | hSK2potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2-HPRD,BioGRID11323678 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
REACTOME_POTASSIUM_CHANNELS 9868All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP 14699All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
BENPORATH_OCT4_TARGETS 290172All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
BENPORATH_NOS_TARGETS 179105All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_UP 282183All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_DN 546362All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
VALK_AML_CLUSTER_16 2617All SZGR genes in this pathway
SETLUR_PROSTATE_CANCER_TMPRSS2_ERG_FUSION_UP 6748All SZGR genes in this pathway
CHICAS_RB1_TARGETS_GROWING 243155All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
OHGUCHI_LIVER_HNF4A_TARGETS_DN 14985All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-14014201Ahsa-miR-140brainAGUGGUUUUACCCUAUGGUAG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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